(Q36827533)

English

The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

scientific article published on May 1989

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scholarly article

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30 September 2019

The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation (English)

1 reference

Europe PubMed Central

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30 September 2019

author name string

T L Black

1

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30 September 2019

B Safer

2

1 reference

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30 September 2019

A Hovanessian

3

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30 September 2019

M G Katze

4

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30 September 2019

language of work or name

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publication date

1 May 1989

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30 September 2019

Journal of Virology

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30 September 2019

63

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30 September 2019

2244-2251

1 reference

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30 September 2019

5

1 reference

Europe PubMed Central

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30 September 2019

Interferon-mediated, double-stranded RNA-dependent protein kinase is inhibited in extracts from vaccinia virus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

The Regulation of Initiation of Mammalian Protein Synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Purification and properties of the replicative intermediate of the RNA bacteriophage R17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Regulation of protein synthesis in HeLa cells. 3. Inhibition during poliovirus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Translational control by adenovirus: lack of virus-associated RNAI during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Adenovirus VAI RNA complexes with the 68 000 Mr protein kinase to regulate its autophosphorylation and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Regulation of translation by poliovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Activation of double-stranded RNA-activated protein kinase in HeLa cells after poliovirus infection does not result in increased phosphorylation of eucaryotic initiation factor-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Regulation of protein synthesis in virus-infected animal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Poliovirus mutant that does not selectively inhibit host cell protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

A heat-sensitive inhibitor in poliovirus-infected cells which selectively blocks phosphorylation of the alpha subunit of eucaryotic initiation factor 2 by the double-stranded RNA-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Translational control of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Inhibition of translation by poliovirus: inactivation of a specific initiation factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

29 September 2017

Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

27 June 2018

Nuclear-cytoplasmic transport and VAI RNA-independent translation of influenza viral messenger RNAs in late adenovirus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

27 June 2018

A mechanism for the control of protein synthesis by adenovirus VA RNAI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

27 June 2018

Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

27 June 2018

Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

27 June 2018

VIRUS-SPECIFIC DOUBLE-STRANDED RNA IN POLIOVIRUS-INFECTED CELLS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

5 September 2018

Patterns of macromolecular synthesis in normal and virus-infected mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

5 September 2018

The host protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

5 September 2018

Rapid decrease in the levels of the double-stranded RNA-dependent protein kinase during virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250642

5 September 2018

Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2B or not 2B: regulation of the catalytic utilization of eIF-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mRNA cap binding proteins: essential factors for initiating translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the interaction of the human c-myc protein with cell nuclei: p62c-myc as a member of a discrete subset of nuclear proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the protein kinase dependent on double-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poliovirus-induced inhibition of host-cell protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2539516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.63.5.2244-2251.1989

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2539516%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2539516%20AND%20SRC:MED&resulttype=core&format=json

30 September 2019

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