(Q36857262)

16 August 2017

Synthetic studies toward (-)-FR901483 using a conjugate allylation to install the C-1 quaternary carbon (English)

1 reference

16 August 2017

Dimitar B Gotchev

1

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16 August 2017

Daniel L Comins

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

1 December 2006

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Journal of Organic Chemistry

16 August 2017

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16 August 2017

71

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16 August 2017

25

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16 August 2017

9393-9402

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An Enantiospecific Synthesis of the Potent Immunosuppressant FR901483 Dr. G. Scheffler and H. Seike contributed equally to this work. We thank Dr. L. B. Pasternack and Dr. D. H. Huang for NMR spectroscopic assistance, and Dr. G. Siuzdak for mass spe

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Enantiopure N-acyldihydropyridones as synthetic intermediates: asymmetric synthesis of benzomorphans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Immunophilin-sensitive protein phosphatase action in cell signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

FR901483, a novel immunosuppressant isolated from Cladobotryum sp. No. 11231. Taxonomy of the producing organism, fermentation, isolation, physico-chemical properties and biological activities.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

A formal total synthesis of (-)-FR901483, using a tandem cationic aza-Cope rearrangement/Mannich cyclization approach

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Asymmetric syntheses of pectenotoxins-4 and -8, part I: synthesis of the C1-C19 subunit

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Enantiopure N-Acyldihydropyridones as Synthetic Intermediates: Asymmetric Syntheses of Indolizidine Alkaloids (-)-205A, (-)-207A, and (-)-235B.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Total synthesis of the marine toxin polycavernoside A via selective macrolactonization of a trihydroxy carboxylic acid

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527541

Stereocontrolled total synthesis of potent immunosuppressant FR901483

4 September 2018

1 reference

12 December 2020

Total synthesis of FR901483

1 reference

12 December 2020

The Mukaiyama-Michael reaction of N-acyl-2,3-dihydro-4-pyridones: regio- and stereoselective synthesis of cis-2,6-disubstituted 1,2,5,6-tetrahydropyridines

1 reference

12 December 2020

Radical carboazidation: expedient assembly of the core structure of various alkaloid families

1 reference

12 December 2020

Nucleophilic Alkylation on Anti-Bredt Iminium Ions. Facile Entry to the Synthesis of 1-Alkylated 2-Azabicyclo[3.3.1]nonanes (Morphans) and 5-Azatricyclo[6.3.1.0(1,5)]dodecane

1 reference

12 December 2020

Synthesis and biological evaluation of a conformationally free seco-analogue of the immunosuppressant FR901483

1 reference

12 December 2020

Tandem cationic aza-cope rearrangement-Mannich cyclization approach to the core structure of FR901483 via a Bridgehead iminium ion

1 reference

12 December 2020

Total synthesis of the immunosuppressant FR901483 via an amidoacrolein cycloaddition

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12 December 2020

N-methoxy-N-acylnitrenium ions: application to the formal synthesis of (+/-)-desmethylamino FR901483

1 reference

12 December 2020

Oxidation of silyl enol ethers by using IBX and IBX.N-oxide complexes: a mild and selective reaction for the synthesis of enones

1 reference

12 December 2020

Identifiers

DOI

10.1021/JO061677T

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16 August 2017

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16 August 2017

PubMed publication ID

17137366

1 reference