(Q36864047)

16 August 2017

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title

Utilizing RNA interference to enhance cancer drug discovery (English)

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16 August 2017

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Elizabeth Iorns

1

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Christopher J Lord

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Christopher J Lord

series ordinal

2

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Alan Ashworth

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4

object named as

Alan Ashworth

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16 August 2017

Nicholas Turner

3

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16 August 2017

1 July 2007

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Nature Reviews Drug Discovery

16 August 2017

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16 August 2017

6

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16 August 2017

556-568

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16 August 2017

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https://scigraph.springernature.com/pub.10.1038/nrd2355

16 August 2017

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cites work

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Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

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In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes.

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Restoration of p53 function leads to tumour regression in vivo

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siRNAs can function as miRNAs

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

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An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

31 March 2020

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Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

31 March 2020

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31 March 2020

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A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.

31 March 2020

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31 March 2020

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

31 March 2020

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High-throughput screening by RNA interference: control of two distinct types of variance

31 March 2020

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3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

31 March 2020

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31 March 2020

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31 March 2020

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RNA interference: mechanisms of action and therapeutic consideration

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD2355

1 reference

PubMed ID

17599085

Dimensions Publication ID

16 August 2017

0 references

1 reference

PubMed ID

17599085