(Q36871580)

16 August 2017

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title

miRNAs in cancer: approaches, aetiology, diagnostics and therapy (English)

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16 August 2017

2

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16 August 2017

Cherie Blenkiron

1

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publication date

1 April 2007

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16 August 2017

Human Molecular Genetics

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16 August 2017

16 Spec No 1

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16 August 2017

R106-13

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

16 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

RNAi therapeutics: a potential new class of pharmaceutical drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA biogenesis: coordinated cropping and dicing

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

microPrimer: the biogenesis and function of microRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

21 January 2018

The microRNA Registry

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

miRBase: microRNA sequences, targets and gene nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Phylogenetic shadowing and computational identification of human microRNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA functions in animal development and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Heterochronic genes and the temporal control of C. elegans development

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Mutations that lead to reiterations in the cell lineages of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Intrinsic and extrinsic regulators of developmental timing: from miRNAs to nutritional cues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Regulatory mutations of mir-48, a C. elegans let-7 family MicroRNA, cause developmental timing defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Identification of tissue-specific microRNAs from mouse

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A microRNA array reveals extensive regulation of microRNAs during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Microarray analysis of microRNA expression in the developing mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A custom microarray platform for analysis of microRNA gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Facile means for quantifying microRNA expression by real-time PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA expression profiling of single whole embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Spatially restricted microRNA directs leaf polarity through ARGONAUTE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA expression in zebrafish embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Oncogenes and tumor-suppressing genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The role of microRNA genes in papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A microRNA polycistron as a potential human oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Activation of an oncogenic microRNA cistron by provirus integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

An E2F/miR-20a autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Post-transcriptional regulation of microRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Multiclass cancer diagnosis using tumor gene expression signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Sequence variants in SLITRK1 are associated with Tourette's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Sequence-specific inhibition of small RNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Histone deacetylase inhibitors: gathering pace

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA deregulation in human thyroid papillary carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA gene expression deregulation in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Extensive modulation of a set of microRNAs in primary glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM056

21 January 2018

Identifiers

DOI

10.1093/HMG/DDM056

1 reference

16 August 2017

1 reference

PubMed ID

17613543