(Q36873695)

16 August 2017

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title

Linking impact to cellular and molecular sequelae of CNS injury: modeling in vivo complexity with in vitro simplicity (English)

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16 August 2017

David F Meaney

8

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ORCID Public Data File 2021

author name string

Jennifer M Spaethling

1

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16 August 2017

Donna M Geddes-Klein

2

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16 August 2017

William J Miller

3

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16 August 2017

Catherine R von Reyn

4

1 reference

16 August 2017

Pallab Singh

5

1 reference

16 August 2017

Mahlet Mesfin

6

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16 August 2017

Steven J Bernstein

7

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16 August 2017

publication date

1 January 2007

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Progress in Brain Research

16 August 2017

published in

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16 August 2017

volume

161

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16 August 2017

page(s)

27-39

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Methods to induce primary and secondary traumatic damage in organotypic hippocampal slice cultures

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

NMDA receptor activation contributes to a portion of the decreased mitochondrial membrane potential and elevated intracellular free calcium in strain-injured neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Vulnerability of central neurons to secondary insults after in vitro mechanical stretch.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Enhanced vulnerability to NMDA toxicity in sublethal traumatic neuronal injury in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Oligodendrocyte progenitor migration in response to injury of glial monolayers requires the polysialic neural cell-adhesion molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Acute alterations in [Ca2+]i in NG108-15 cells subjected to high strain rate deformation and chemical hypoxia: an in vitro model for neural trauma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Temporal development of hippocampal cell death is dependent on tissue strain but not strain rate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Group I metabotropic receptor antagonism blocks depletion of calcium stores and reduces potentiated capacitative calcium entry in strain-injured neurons and astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Protective effects of extracellular glutathione against Zn2+-induced cell death in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Spreading depression expands traumatic injury in neocortical brain slices

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Material properties of porcine parietal cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

The role of extracellular signal-regulated kinase in cognitive and motor deficits following experimental traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Physiologic, histopathologic, and cineradiographic characterization of a new fluid-percussion model of experimental brain injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A new model for rapid stretch-induced injury of cells in culture: characterization of the model using astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Relative susceptibility of elements of the cerebral cortex to mechanical trauma in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuroprotective and nootropic actions of a novel cyclized dipeptide after controlled cortical impact injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuroprotective effects of group III mGluR in traumatic neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuroprotective effects of novel small peptides in vitro and after brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanoporation induced by diffuse traumatic brain injury: an irreversible or reversible response to injury?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical strain injury increases intracellular sodium and reverses Na+/Ca2+ exchange in cortical astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Antagonism of group I metabotropic glutamate receptors and PLC attenuates increases in inositol trisphosphate and reduces reactive gliosis in strain-injured astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuroprotection, excitotoxicity and NMDA antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

An in vitro model of neural trauma: device characterization and calcium response to mechanical stretch

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Susceptibility of hippocampal neurons to mechanically induced injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanisms and consequences of neuronal stretch injury in vitro differ with the model of trauma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Animate models of human head injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Influence of the type of intracranial lesion on outcome from severe head injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Diffuse axonal injury and traumatic coma in the primate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Enhancement of AMPA-mediated current after traumatic injury in cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical injury modulates AMPA receptor kinetics via an NMDA receptor-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

The nature, distribution and causes of traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Laser microbeam surgery: ultrastructural changes associated with neurite transection in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A new model for diffuse brain injury by rotational acceleration: I model, gross appearance, and astrocytosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

The Yin and Yang of NMDA receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Astrocytes generate isoprostanes in response to trauma or oxygen radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Potentiation of GABA(A) currents after mechanical injury of cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic injury in vitro induces IEG mRNAs in cultured glial cells, suppressed by co-culture with neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Alterations in phosphatidylcholine metabolism of stretch-injured cultured rat astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic brain injury in the United States: research and programs of the Centers for Disease Control and Prevention (CDC)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

High rate shear strain of three-dimensional neural cell cultures: a new in vitro traumatic brain injury model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

An in vitro model of traumatic neuronal injury: loading rate-dependent changes in acute cytosolic calcium and lactate dehydrogenase release

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Controlled cortical impact: a new experimental brain injury model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Proximal segment retraction increases the probability of nerve cell survival after dendrite transection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuronal survival or death after dendrite transection close to the perikaryon: correlation with electrophysiologic, morphologic, and ultrastructural changes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A device to study the initiation and propagation of calcium transients in cultured neurons after mechanical stretch

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanics

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A mechanistic analysis of nondisruptive axonal injury: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Magnesium protects against neurological deficit after brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Stretch-induced injury of cultured neuronal, glial, and endothelial cells. Effect of polyethylene glycol-conjugated superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Biomechanical analysis of experimental diffuse axonal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mitogen-activated protein kinase inhibition in traumatic brain injury: in vitro and in vivo effects

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical characterization of an in vitro device designed to quantitatively injure living brain tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

In vitro central nervous system models of mechanically induced trauma: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Neuroprotective effects of selective group II mGluR activation in brain trauma and traumatic neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical injury to neuronal/glial cultures in microplates: role of NMDA receptors and pH in secondary neuronal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Internal cavitation in simple head impact model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Stretch injury causes calpain and caspase-3 activation and necrotic and apoptotic cell death in septo-hippocampal cell cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Biomarkers of proteolytic damage following traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Update of neuropathology and neurological recovery after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical trauma induces immediate changes in neuronal network activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Regional, directional, and age-dependent properties of the brain undergoing large deformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Increased jun immunoreactivity in an in vitro model of mammalian spinal neuron physical injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic neuronal injury in cortical cell culture is attenuated by 21-aminosteroids.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanisms of cell death and neuroprotection by poloxamer 188 after mechanical trauma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Apoptosis mediates cell death following traumatic injury in rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Cellular reactivity to mechanical axonal injury in an organotypic in vitro model of neurotrauma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

The role of metabotropic glutamate receptor 5 in learning and memory processes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Repeated mild injury causes cumulative damage to hippocampal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A Model of Parasagittal Controlled Cortical Impact in the Mouse: Cognitive and Histopathologic Effects

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

High tolerance and delayed elastic response of cultured axons to dynamic stretch injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Impaired axonal transport and altered axolemmal permeability occur in distinct populations of damaged axons following traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Mechanical perturbation of cultured cortical neurons reveals a stretch-induced delayed depolarization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Inhibition of the electrogenic Na pump underlies delayed depolarization of cortical neurons after mechanical injury or glutamate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic neuronal injury in vitro is attenuated by NMDA antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Biomechanical Aspects of a Fluid Percussion Model of Brain Injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic Brain Injury in the United States: A Public Health Perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Secretion of matrix metalloproteinase-2 and -9 after mechanical trauma injury in rat cortical cultures and involvement of MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Calcium homeostasis following traumatic neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic injury of cortical neurons causes changes in intracellular calcium stores and capacitative calcium influx

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

S100B protein is released by in vitro trauma and reduces delayed neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Diffuse axonal injury due to lateral head rotation in a rat model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Reduction of voltage-dependent Mg2+ blockade of NMDA current in mechanically injured neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

A proposed injury threshold for mild traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Predicting unconsciousness from a pediatric brain injury threshold

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Intracellular free calcium dynamics in stretch-injured astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

Experimental brain damage from fluid pressures due to impact acceleration. 3. Morphological observations

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2961003-0

7 January 2021

10.1016/S0079-6123(06)61003-0

Identifiers

DOI

1 reference

16 August 2017

1 reference