(Q36905831)

17 August 2017

1 reference

title

Acetaminophen safety and hepatotoxicity--where do we go from here? (English)

1 reference

17 August 2017

1 reference

1 reference

Patrick J Amar

1

1 reference

17 August 2017

Eugene R Schiff

series ordinal

2

1 reference

17 August 2017

language of work or name

English

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publication date

1 July 2007

1 reference

Expert Opinion on Drug Safety

17 August 2017

1 reference

17 August 2017

6

1 reference

17 August 2017

341-355

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17 August 2017

4

1 reference

Mechanism of action of paracetamol

17 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Paracetamol exerts a spinal, tropisetron-reversible, antinociceptive effect in an inflammatory pain model in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Orally administered paracetamol does not act locally in the rat formalin test: evidence for a supraspinal, serotonin-dependent antinociceptive mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Mechanism of acetaminophen inhibition of cyclooxygenase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Genetic predisposition to drug-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Dose-dependent pharmacokinetics of acetaminophen: evidence of glutathione depletion in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Influence of age-dependent pharmacokinetics and metabolism on acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acute liver necrosis following overdose of paracetamol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Liver damage and impaired glucose tolerance after paracetamol overdosage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Measurement of serum acetaminophen-protein adducts in patients with acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

The influence of diet upon liver function tests and serum lipids in healthy male volunteers resident in a Phase I unit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Transaminase elevation on placebo during phase I trials: prevalence and significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Paracetamol poisoning in children and hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Ethanol binging enhances hepatic microvascular responses to acetaminophen in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Severe acetaminophen toxicity in a patient receiving isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Pharmacokinetics of zidovudine and acetaminophen in a patient on chronic acetaminophen therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Cytochrome P450IIE1 is elevated in lymphocytes from poorly controlled insulin-dependent diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Hepatotoxicity due to repeated intake of low doses of paracetamol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

The effects of food restriction in man on hepatic metabolism of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Legislation restricting paracetamol sales and patterns of self-harm and death from paracetamol-containing preparations in Scotland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Restricting sales of paracetamol tablets: effect on deaths and emergency admissions for poisoning in Scotland 1991 - 2002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Etiology and outcome for 295 patients with acute liver failure in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Paracetamol overdose in a liver transplantation centre: an 8-year experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen toxicity in an urban county hospital

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Multicenter, randomized, double-blind, active-controlled, parallel-group trial of the long-term (6-12 months) safety of acetaminophen in adult patients with osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Retrospective analysis of transient elevations in alanine aminotransferase during long-term treatment with acetaminophen in osteoarthritis clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Therapeutic misadventures with acetaminophen: hepatoxicity after multiple doses in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Outcome of acetaminophen overdose in pediatric patients and factors contributing to hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acute versus chronic alcohol consumption in acetaminophen-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Effect of maximal daily doses of acetaminophen on the liver of alcoholic patients: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Influence of acute and chronic alcohol intake on the clinical course and outcome in acetaminophen overdose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Increased metabolism of acetaminophen in chronically alcoholic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Association of acetaminophen hepatotoxicity with fasting and ethanol use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.4.341

21 January 2018

Identifiers

DOI

10.1517/14740338.6.4.341

1 reference

release_zvvtuug74bgundpyq3st2tr5ca

17 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zvvtuug74bgundpyq3st2tr5ca

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference