(Q36915566)

17 August 2017

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology (English)

1 reference

17 August 2017

1 reference

1 reference

Oliver J Britton

1

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Alfonso Bueno-Orovio

object named as

Alfonso Bueno-Orovio

2

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Blanca Rodriguez

object named as

Blanca Rodriguez

7

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author name string

Karel Van Ammel

3

1 reference

17 August 2017

Hua Rong Lu

4

1 reference

17 August 2017

Rob Towart

5

1 reference

17 August 2017

David J Gallacher

6

1 reference

17 August 2017

language of work or name

English

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publication date

20 May 2013

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Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

1 reference

17 August 2017

110

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17 August 2017

E2098-105

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17 August 2017

23

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mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Bridging experiments, models and simulations: an integrative approach to validation in computational cardiac electrophysiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Exploiting mathematical models to illuminate electrophysiological variability between individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

A model of canine purkinje cell electrophysiology and Ca(2+) cycling: rate dependence, triggered activity, and comparison to ventricular myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Factors affecting the degree of QT prolongation with drug challenge in a large cohort of normal volunteers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Multiple models to capture the variability in biological neurons and networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Regression analysis for constraining free parameters in electrophysiological models of cardiac cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Diastolic intracellular calcium-membrane voltage coupling gain and postshock arrhythmias: role of purkinje fibers and triggered activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Reliable neuromodulation from circuits with variable underlying structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Multiscale modelling of drug-induced effects on cardiac electrophysiological activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

A methodology for performing global uncertainty and sensitivity analysis in systems biology.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Compensation for variable intrinsic neuronal excitability by circuit-synaptic interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

How multiple conductances determine electrophysiological properties in a multicompartment model

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

3D current-voltage-time surfaces unveil critical repolarization differences underlying similar cardiac action potentials: A model study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Impact of ionic current variability on human ventricular cellular electrophysiology.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Atrial cell action potential parameter fitting using genetic algorithms.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

Both beta-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of I(Ks) channel blockers in vitro

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677477

A Comparison of Three Methods for Selecting Values of Input Variables in the Analysis of Output from a Computer Code

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1304382110

Chaste: A test-driven approach to software development for biological modelling

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1304382110

Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23690584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23690584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1304382110

1 reference

17 August 2017

0 references

1 reference

17 August 2017

1 reference