(Q36954453)

17 August 2017

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage (English)

1 reference

17 August 2017

0 references

metastatic osteosarcoma

1 reference

10

Mary L Bouxsein

1 reference

17 August 2017

Seth D Berman

1

1 reference

17 August 2017

Eliezer Calo

2

1 reference

17 August 2017

Allison S Landman

3

1 reference

17 August 2017

Paul S Danielian

4

1 reference

17 August 2017

Emily S Miller

5

1 reference

17 August 2017

Julie C West

6

1 reference

17 August 2017

Borel Djouedjong Fonhoue

7

1 reference

17 August 2017

Alicia Caron

8

1 reference

17 August 2017

Roderick Bronson

9

1 reference

17 August 2017

Siddhartha Mukherjee

11

1 reference

17 August 2017

Jacqueline A Lees

12

1 reference

17 August 2017

language of work or name

English

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publication date

12 August 2008

1 reference

17 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

17 August 2017

105

1 reference

17 August 2017

11851-11856

1 reference

17 August 2017

33

1 reference

The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

A review of clinical and molecular prognostic factors in osteosarcoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Mesenchymal stem cell features of Ewing tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Molecular pathogenesis of osteosarcoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Li-Fraumeni syndrome: a p53 family affair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Developmental defects and tumor predisposition in Rb mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

p53 and the Li-Fraumeni syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575280

Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma

4 September 2018

1 reference

12 December 2020

Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma

1 reference

12 December 2020

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

12 December 2020

Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma

1 reference

12 December 2020

TP53Mutations and Outcome in Osteosarcoma: A Prospective, Multicenter Study

1 reference

12 December 2020

Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0805462105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

1 reference