(Q36959806)

English

Extinction of insulin gene expression in hybrids between beta cells and fibroblasts is accompanied by loss of the putative beta-cell-specific transcription factor IEF1.

scientific article published on March 1991

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

17 August 2017

Extinction of insulin gene expression in hybrids between beta cells and fibroblasts is accompanied by loss of the putative beta-cell-specific transcription factor IEF1. (English)

1 reference

Europe PubMed Central

17 August 2017

author name string

D Leshkowitz

1

1 reference

Europe PubMed Central

17 August 2017

M D Walker

2

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

1 March 1991

1 reference

Europe PubMed Central

17 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

17 August 2017

11

1 reference

Europe PubMed Central

17 August 2017

1547-1552

1 reference

Europe PubMed Central

17 August 2017

3

1 reference

Europe PubMed Central

17 August 2017

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

The level of expression of the rat growth hormone gene in liver tumor cells is at least eight orders of magnitude less than that in anterior pituitary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Regulation of pigment synthesis in mammalian cells, as studied by somatic hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Expression of differentiated functions in hepatoma cell hybrids. I. Tyrosine aminotransferase in hepatoma-fibroblast hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Regulation of rat insulin 1 gene expression: evidence for negative regulation in nonpancreatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Transcriptional "silencer" element in rat repetitive sequences associated with the rat insulin 1 gene locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF1/LFB1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Transcriptional repression in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

29 September 2017

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Extinction of growth hormone expression in somatic cell hybrids involves repression of the specific trans-activator GHF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Characterization of the two nonallelic genes encoding mouse preproinsulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Extinction of an immunoglobulin kappa promoter in cell hybrids is mediated by the octamer motif and correlates with suppression of Oct-2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

27 June 2018

Disproportionate expression of the two nonallelic rat insulin genes in a pancreatic tumor is due to translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

4 September 2018

Role of the octamer motif in hybrid cell extinction of immunoglobulin gene expression: extinction is dominant in a two enhancer system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

4 September 2018

Negative regulation of human insulin gene expression by the 5'-flanking region in non-pancreatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369442

4 September 2018

The structure and evolution of the two nonallelic rat preproinsulin genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Insulinoma Hybrids Produce Proinsulin-like Material

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and evolution of the insulin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two mechanisms for the extinction of gene expression in hybrid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible extinction of insulin gene expression in insulinoma X fibroblast somatic cell hybrids

1 reference

https://pubmed.ncbi.nlm.nih.gov/1996108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.11.3.1547

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36959806&oldid=1514635541"