(Q37051667)

17 August 2017

1 reference

title

Possible mechanisms of disease development in tuberous sclerosis (English)

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17 August 2017

2

Sergiusz Jozwiak

1 reference

PubMed ID

18177819

Pawel Krzysztof Wlodarski

17 August 2017

series ordinal

3

object named as

Pawel Wlodarski

1 reference

17 August 2017

Jaroslaw Jozwiak

1

1 reference

17 August 2017

1 January 2008

1 reference

Lancet Oncology Commission

17 August 2017

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17 August 2017

9

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17 August 2017

73-79

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17 August 2017

1

1 reference

Identification and characterization of the tuberous sclerosis gene on chromosome 16

17 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Positive and negative regulation of TSC2 activity and its effects on downstream effectors of the mTOR pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Clinical and genotype studies of cardiac tumors in 154 patients with tuberous sclerosis complex

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Differential localization of hamartin and tuberin and increased S6 phosphorylation in a tuber

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Subependymal giant cell astrocytoma with positive tuberin expression--case report

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Apparent preferential loss of heterozygosity at TSC2 over TSC1 chromosomal region in tuberous sclerosis hamartomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Loss of heterozygosity in tuberous sclerosis hamartomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Tsc2 is not a critical target of Akt during normal Drosophila development

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Brain tumor formation in tuberous sclerosis depends on Erk activation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Expression of ICAM-1, TNF-alpha, NF kappa B, and MAP kinase in tubers of the tuberous sclerosis complex

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Platelet-derived growth factor-induced p42/44 mitogen-activated protein kinase activation and cellular growth is mediated by reactive oxygen species in the absence of TSC2/tuberin

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Estrogen-induced smooth muscle cell growth is regulated by tuberin and associated with altered activation of platelet-derived growth factor receptor-beta and ERK-1/2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

The tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) provokes a prolonged morphologic response and ERK activation in Tsc2-null renal tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Phosphorylation of tuberin as a novel mechanism for somatic inactivation of the tuberous sclerosis complex proteins in brain lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Tsc1 haploinsufficiency without mammalian target of rapamycin activation is sufficient for renal cyst formation in Tsc1+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

Abnormal cortical cells and astrocytomas in the Eker rat model of tuberous sclerosis complex

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970411-4

7 January 2021

10.1016/S1470-2045(07)70411-4

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

18177819