(Q37063035)

18 August 2017

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title

Metabolic flux analysis and metabolic engineering of microorganisms (English)

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18 August 2017

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3

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18 August 2017

1

Hyun Uk Kim

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18 August 2017

Tae Yong Kim

2

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18 August 2017

16 October 2007

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18 August 2017

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18 August 2017

4

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18 August 2017

113-120

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18 August 2017

2

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In silico prediction and validation of the importance of the Entner-Doudoroff pathway in poly(3-hydroxybutyrate) production by metabolically engineered Escherichia coli

18 August 2017

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Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation

21 January 2018

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Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets.

21 January 2018

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Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation

21 January 2018

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Cleaning up with genomics: applying molecular biology to bioremediation

21 January 2018

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The path forward for biofuels and biomaterials

21 January 2018

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Challenges in engineering microbes for biofuels production.

21 January 2018

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Toward a science of metabolic engineering

21 January 2018

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Metabolic fluxes and metabolic engineering

21 January 2018

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Systems biotechnology for strain improvement

21 January 2018

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It is all about metabolic fluxes

21 January 2018

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Metabolic networks in motion: 13C-based flux analysis

21 January 2018

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13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches

21 January 2018

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13C metabolic flux analysis

21 January 2018

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High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints.

21 January 2018

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Genome-scale models of microbial cells: evaluating the consequences of constraints

21 January 2018

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Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering.

21 January 2018

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A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks

21 January 2018

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Two approaches for metabolic pathway analysis?

21 January 2018

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Comparison of network-based pathway analysis methods

21 January 2018

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The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities

21 January 2018

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An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

21 January 2018

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A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information

21 January 2018

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Systems properties of the Haemophilus influenzae Rd metabolic genotype

21 January 2018

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Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis

21 January 2018

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Genome-scale metabolic model of Helicobacter pylori 26695.

21 January 2018

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Expanded metabolic reconstruction of Helicobacter pylori (iIT341 GSM/GPR): an in silico genome-scale characterization of single- and double-deletion mutants

21 January 2018

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Genome-scale analysis of Mannheimia succiniciproducens metabolism.

21 January 2018

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Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

21 January 2018

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Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model

21 January 2018

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Integrating high-throughput and computational data elucidates bacterial networks

21 January 2018

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A genome-scale computational study of the interplay between transcriptional regulation and metabolism

21 January 2018

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Regulatory on/off minimization of metabolic flux changes after genetic perturbations

21 January 2018

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Stoichiometric network theory for nonequilibrium biochemical systems

21 January 2018

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Thermodynamic constraints for biochemical networks.

21 January 2018

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Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism

21 January 2018

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Genome-scale thermodynamic analysis of Escherichia coli metabolism

21 January 2018

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Thermodynamics-based metabolic flux analysis

21 January 2018

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Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast

21 January 2018

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Identification of genome-scale metabolic network models using experimentally measured flux profiles

21 January 2018

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Development of network-based pathway definitions: the need to analyze real metabolic networks

21 January 2018

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Large-scale in vivo flux analysis shows rigidity and suboptimal performance of Bacillus subtilis metabolism

21 January 2018

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Evolutionary programming as a platform for in silico metabolic engineering

21 January 2018

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Analysis of optimality in natural and perturbed metabolic networks

21 January 2018

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Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli.

21 January 2018

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Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

21 January 2018

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An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems

21 January 2018

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In silico design and adaptive evolution of Escherichia coli for production of lactic acid.

21 January 2018

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OptStrain: a computational framework for redesign of microbial production systems.

21 January 2018

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Genome-scale in silico aided metabolic analysis and flux comparisons of Escherichia coli to improve succinate production.

21 January 2018

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In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production

21 January 2018

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Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth

21 January 2018

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Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes

21 January 2018

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Systems biology: a brief overview

21 January 2018

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Exploiting biological complexity for strain improvement through systems biology.

21 January 2018

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The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens

21 January 2018

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Genome-scale reconstruction of metabolic network in Bacillus subtilis based on high-throughput phenotyping and gene essentiality data

21 January 2018

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Characterization of metabolism in the Fe(III)-reducing organism Geobacter sulfurreducens by constraint-based modeling

21 January 2018

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Analysis of growth of Lactobacillus plantarum WCFS1 on a complex medium using a genome-scale metabolic model.

21 January 2018

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Modeling Lactococcus lactis using a genome-scale flux model

21 January 2018

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Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets

21 January 2018

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GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

21 January 2018

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Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes

21 January 2018

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Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation

21 January 2018

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In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network.

21 January 2018

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Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism

21 January 2018

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Modeling methanogenesis with a genome-scale metabolic reconstruction of Methanosarcina barkeri

21 January 2018

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Global reconstruction of the human metabolic network based on genomic and bibliomic data

21 January 2018

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Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/B712395G

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18 August 2017

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PubMed ID

18213404