(Q37099942)

English

The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1.

scientific article published on 15 December 2008

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scholarly article

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18 January 2020

The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1 (English)

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18 January 2020

Dmitry A. Gordenin

5

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18 January 2020

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Wenjian Ma

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18 January 2020

Vijayalakshmi Panduri

2

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18 January 2020

Joan F Sterling

3

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18 January 2020

Bennett Van Houten

4

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18 January 2020

Michael A Resnick

6

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18 January 2020

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15 December 2008

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18 January 2020

Molecular and Cellular Biology

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18 January 2020

29

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18 January 2020

1212-1221

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18 January 2020

5

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18 January 2020

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

1 reference

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Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

1 reference

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14 September 2017

Processing of DNA damage clusters in human cells: current status of knowledge

1 reference

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14 September 2017

Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion.

1 reference

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Break-induced replication and telomerase-independent telomere maintenance require Pol32.

1 reference

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14 September 2017

Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways

1 reference

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14 September 2017

The mechanics of base excision repair, and its relationship to aging and disease

1 reference

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14 September 2017

Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta

1 reference

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14 September 2017

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks

1 reference

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14 September 2017

Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins

1 reference

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14 September 2017

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

1 reference

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14 September 2017

Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

1 reference

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14 September 2017

The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer

1 reference

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14 September 2017

Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts

1 reference

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14 September 2017

Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae

1 reference

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14 September 2017

Biological consequences of free radical-damaged DNA bases.

1 reference

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14 September 2017

Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

1 reference

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14 September 2017

Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

1 reference

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14 September 2017

Base excision repair processing of radiation-induced clustered DNA lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites

1 reference

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14 September 2017

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

1 reference

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14 September 2017

Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

1 reference

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14 September 2017

Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues

1 reference

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14 September 2017

The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta

1 reference

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14 September 2017

DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories

1 reference

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14 September 2017

Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

14 September 2017

Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII

1 reference

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14 September 2017

An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining

1 reference

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14 September 2017

Instability and decay of the primary structure of DNA

1 reference

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14 September 2017

Recombinant replication protein A: expression, complex formation, and functional characterization

1 reference

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14 September 2017

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

1 reference

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14 September 2017

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

1 reference

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14 September 2017

Spliced early mRNAs of simian virus 40

1 reference

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14 September 2017

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

1 reference

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29 September 2017

Radiation-induced heat-labile sites that convert into DNA double-strand breaks

1 reference

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27 June 2018

DNA glycosylases in the base excision repair of DNA

1 reference

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27 June 2018

Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid

1 reference

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27 June 2018

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control

1 reference

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27 June 2018

Reduction in frataxin causes progressive accumulation of mitochondrial damage.

1 reference

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3 September 2018

Double-strand DNA break formation mediated by flap endonuclease-1.

1 reference

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3 September 2018

Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death

1 reference

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3 September 2018

Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2643827

3 September 2018

Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

POL32, a subunit of the Saccharomyces cerevisiae DNA polymerase delta, defines a link between DNA replication and the mutagenic bypass repair pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of gamma ray-induced S1 nuclease hypersensitive sites in yeast depends on homologous mitotic recombination and a RAD18-dependent function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The repair of double-strand breaks and S1 nuclease-sensitive sites can be monitored chromosome-specifically in Saccharomyces cerevisiae using pulse-field gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How the cell deals with DNA nicks

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pol32 Subunit of DNA Polymerase δ Contains Separable Domains for Processive Replication and Proliferating Cell Nuclear Antigen (PCNA) Binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionizing radiation induced DNA damage: identities and DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and repair of closely opposed pyrimidine dimers in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of a Methylated DNA Standard, and Its Stability on Storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19075004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01499-08

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19075004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19075004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19075004%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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