(Q37170851)

18 August 2017

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title

The actin cytoskeleton in cancer cell motility (English)

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18 August 2017

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Erik Sahai

2

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Michael F. Olson

object named as

Michael F Olson

series ordinal

1

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language of work or name

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23 May 2008

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Clinical & Experimental Metastasis

18 August 2017

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18 August 2017

26

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18 August 2017

273-287

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18 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s10585-008-9174-2

18 August 2017

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cites work

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

1 reference

12 December 2020

Formin-induced nucleation of actin filaments

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12 December 2020

Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin

1 reference

12 December 2020

Life and times of a cellular bleb

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12 December 2020

Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor

1 reference

12 December 2020

Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42

1 reference

12 December 2020

The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors

1 reference

12 December 2020

Tumor cell migration in three dimensions

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12 December 2020

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

1 reference

12 December 2020

Integrin-linked kinase phosphorylates the myosin phosphatase target subunit at the inhibitory site in platelet cytoskeleton

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12 December 2020

Intravital imaging and cell invasion

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12 December 2020

The S100A4 Metastasis Factor Regulates Cellular Motility via a Direct Interaction with Myosin-IIA

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12 December 2020

PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE.

1 reference

12 December 2020

Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension

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12 December 2020

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

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12 December 2020

A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes

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12 December 2020

[Screening of a sub-clone of human breast cancer cells with high metastasis potential].

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12 December 2020

Myosin light chain kinase inhibitors can block invasion and adhesion of human pancreatic cancer cell lines

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12 December 2020

Domain organization of chicken gizzard myosin light chain kinase deduced from a cloned cDNA.

1 reference

12 December 2020

The cofilin pathway in breast cancer invasion and metastasis

1 reference

12 December 2020

Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.

1 reference

12 December 2020

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

1 reference

12 December 2020

Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

1 reference

12 December 2020

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization

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12 December 2020

The Rho family GTPase Rif induces filopodia through mDia2.

1 reference

12 December 2020

Formins and VASPs may co-operate in the formation of filopodia.

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12 December 2020

Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase

1 reference

12 December 2020

Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton

1 reference

12 December 2020

Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.

1 reference

12 December 2020

Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy.

1 reference

12 December 2020

Calvasculin, as a factor affecting the microfilament assemblies in rat fibroblasts transfected by src gene

1 reference

12 December 2020

Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

1 reference

12 December 2020

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

1 reference

12 December 2020

Redox-dependent downregulation of Rho by Rac.

1 reference

12 December 2020

Role of fascin in filopodial protrusion

1 reference

12 December 2020

RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion.

1 reference

12 December 2020

Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells

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12 December 2020

Src phosphorylation of cortactin enhances actin assembly

1 reference

12 December 2020

Intravital imaging of cell movement in tumours

1 reference

12 December 2020

Roles of fascin in cell adhesion and motility

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12 December 2020

Crawling toward a unified model of cell mobility: spatial and temporal regulation of actin dynamics.

1 reference

12 December 2020

Cellular motility driven by assembly and disassembly of actin filaments

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12 December 2020

Regulation of actin filament assembly by Arp2/3 complex and formins

1 reference

12 December 2020

Roles of cortactin in tumor pathogenesis

1 reference

12 December 2020

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells

1 reference

12 December 2020

DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis

1 reference

12 December 2020

Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart

1 reference

12 December 2020

Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II.

1 reference

12 December 2020

Identification of differentially expressed genes in microsatellite stable HNPCC and sporadic colon cancer

1 reference

12 December 2020

Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase

1 reference

12 December 2020

The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

1 reference

12 December 2020

Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity

1 reference

12 December 2020

Specification of actin filament function and molecular composition by tropomyosin isoforms

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12 December 2020

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

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12 December 2020

Cofilin produces newly polymerized actin filaments that are preferred for dendritic nucleation by the Arp2/3 complex

1 reference

12 December 2020

Myosin phosphorylation by human cdc42-dependent S6/H4 kinase/gammaPAK from placenta and lymphoid cells

1 reference

12 December 2020

Invadopodia and podosomes in tumor invasion

1 reference

12 December 2020

Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility

1 reference

12 December 2020

Differential roles of Rho-kinase and myosin light chain kinase in regulating shape, adhesion, and migration of HT1080 fibrosarcoma cells

1 reference

12 December 2020

The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration

1 reference

12 December 2020

Structural basis of protein phosphatase 1 regulation

1 reference

12 December 2020

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

1 reference

12 December 2020

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

1 reference

12 December 2020

Surface activity and locomotion of Fundulus deep cells during blastula and gastrula stages

1 reference

12 December 2020

Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon

1 reference

12 December 2020

Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow.

1 reference

12 December 2020

Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge

1 reference

12 December 2020

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

1 reference

12 December 2020

Collagen telopeptides (cross-linking sites) play a role in collagen gel lattice contraction

1 reference

12 December 2020

Non-muscle myosin heavy chain as a possible target for protein encoded by metastasis-related mts-1 gene

1 reference

12 December 2020

Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

1 reference

12 December 2020

Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin

1 reference

12 December 2020

Modeling tissue morphogenesis and cancer in 3D.

1 reference

12 December 2020

The many faces of actin: matching assembly factors with cellular structures

1 reference

12 December 2020

RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability

1 reference

12 December 2020

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

1 reference

12 December 2020

Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase

1 reference

12 December 2020

The beta-thymosin/WH2 fold: multifunctionality and structure

1 reference

12 December 2020

Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle

1 reference

12 December 2020

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

1 reference

12 December 2020

Phosphorylation of protein phosphatase type-1 inhibitory proteins by integrin-linked kinase and cyclic nucleotide-dependent protein kinases

1 reference

12 December 2020

The way things move: looking under the hood of molecular motor proteins

1 reference

12 December 2020

Non-equilibration of hydrostatic pressure in blebbing cells.

1 reference

12 December 2020

Myosin at work: motor adaptations for a variety of cellular functions

1 reference

12 December 2020

Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle

1 reference

12 December 2020

RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking

1 reference

12 December 2020

Reaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptors

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12 December 2020

Mechanisms of cancer cell invasion

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12 December 2020

Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase

1 reference

12 December 2020

WAVE signalling: from biochemistry to biology

1 reference

12 December 2020

Increased expression of myosin light chain kinase mRNA is related to metastasis in non-small cell lung cancer.

1 reference

12 December 2020

Beginning and ending an actin filament: control at the barbed end.

1 reference

12 December 2020

The essential role of profilin in the assembly of actin for microspike formation

1 reference

12 December 2020

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes

1 reference

12 December 2020

Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms.

1 reference

12 December 2020

Proteolytic and non-proteolytic migration of tumour cells and leucocytes

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12 December 2020

Cancer spread and micrometastasis development: quantitative approaches for in vivo models.

1 reference

12 December 2020

Illuminating the metastatic process

1 reference

12 December 2020

EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells

1 reference

12 December 2020

Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

1 reference

12 December 2020

Structure, function, and evolution of the beta-thymosin/WH2 (WASP-Homology2) actin-binding module

1 reference

12 December 2020

Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex.

1 reference

12 December 2020

Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

1 reference

12 December 2020

Tropomyosin isoforms: divining rods for actin cytoskeleton function

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12 December 2020

Gastrin induces over-expression of genes involved in human U373 glioblastoma cell migration.

1 reference

12 December 2020

Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement

1 reference

12 December 2020

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1 reference

12 December 2020

Capping protein: new insights into mechanism and regulation.

1 reference

12 December 2020

ROCK1 phosphorylates and activates zipper-interacting protein kinase

1 reference

12 December 2020

Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells

1 reference

12 December 2020

3-phosphoinositide-dependent kinase 1 deficiency perturbs Toll-like receptor signaling events and actin cytoskeleton dynamics in dendritic cells.

1 reference

12 December 2020

ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo

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12 December 2020

Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II

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12 December 2020

On the stiffness of the natural actin filament decorated with alexa fluor tropomyosin

1 reference

12 December 2020

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

1 reference

12 December 2020

Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis.

1 reference

12 December 2020

Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics

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12 December 2020

Regulation of the actin cytoskeleton by PIP2 in cytokinesis

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12 December 2020

Myosin phosphatase: structure, regulation and function

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12 December 2020

LIM kinases: function, regulation and association with human disease

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12 December 2020

Rho GTPases: biochemistry and biology

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12 December 2020

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

1 reference

12 December 2020

Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

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12 December 2020

ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells

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12 December 2020

Dependence of metastatic cancer cell invasion on MLCK-catalyzed phosphorylation of myosin regulatory light chain

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12 December 2020

S100A4, a mediator of metastasis

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12 December 2020

Profilin: emerging concepts and lingering misconceptions

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12 December 2020

Mechanism and function of formins in the control of actin assembly

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12 December 2020

Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition

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12 December 2020

Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase

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12 December 2020

Two distinct actin networks drive the protrusion of migrating cells

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12 December 2020

10.1007/S10585-008-9174-2

Identifiers

DOI

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18 August 2017

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PubMed ID

18498004