(Q37171800)

18 August 2017

1 reference

title

The genetics and immunopathogenesis of inflammatory bowel disease (English)

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inflammatory bowel diseases

18 August 2017

0 references

inflammation

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author name string

Judy H Cho

series ordinal

1

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PubMed ID

18500230

18 August 2017

language of work or name

1 reference

1 June 2008

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Nature Reviews Immunology

18 August 2017

1 reference

18 August 2017

8

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18 August 2017

458-466

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18 August 2017

6

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Inflammatory Bowel Disease

18 August 2017

1 reference

Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences

31 March 2020

1 reference

Unravelling the pathogenesis of inflammatory bowel disease

31 March 2020

1 reference

Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota

31 March 2020

1 reference

A second generation human haplotype map of over 3.1 million SNPs

31 March 2020

1 reference

Genome-wide association studies: theoretical and practical concerns

31 March 2020

1 reference

Genome-wide association studies for common diseases and complex traits

31 March 2020

1 reference

The genetics of inflammatory bowel disease

31 March 2020

1 reference

Genetic epidemiology in inflammatory bowel disease

31 March 2020

1 reference

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

31 March 2020

1 reference

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.

31 March 2020

1 reference

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

31 March 2020

1 reference

Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses

31 March 2020

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

1 reference

Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

31 March 2020

1 reference

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

31 March 2020

1 reference

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

31 March 2020

1 reference

Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.

31 March 2020

1 reference

NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population.

31 March 2020

1 reference

Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease

31 March 2020

1 reference

Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease

31 March 2020

1 reference

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

31 March 2020

1 reference

Functional consequences of NOD2 (CARD15) mutations

31 March 2020

1 reference

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

31 March 2020

1 reference

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

31 March 2020

1 reference

Activation of nuclear factor kappa B inflammatory bowel disease

31 March 2020

1 reference

Chronic stimulation of Nod2 mediates tolerance to bacterial products

31 March 2020

1 reference

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

31 March 2020

1 reference

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

31 March 2020

1 reference

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

31 March 2020

1 reference

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

31 March 2020

1 reference

Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

31 March 2020

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

31 March 2020

1 reference

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

31 March 2020

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

31 March 2020

1 reference

Unveiling the roles of autophagy in innate and adaptive immunity

31 March 2020

1 reference

Autophagy in innate immunity against intracellular bacteria

31 March 2020

1 reference

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

31 March 2020

1 reference

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

31 March 2020

1 reference

Human IRGM induces autophagy to eliminate intracellular mycobacteria

31 March 2020

1 reference

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

31 March 2020

1 reference

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

31 March 2020

1 reference

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

31 March 2020

1 reference

Increased expression of interleukin 17 in inflammatory bowel disease

31 March 2020

1 reference

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

31 March 2020

1 reference

Transforming growth factor-beta induces development of the T(H)17 lineage

31 March 2020

1 reference

31 March 2020

1 reference

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

31 March 2020

1 reference

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

31 March 2020

1 reference

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

31 March 2020

1 reference

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

31 March 2020

1 reference

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

31 March 2020

1 reference

Interleukin-23 drives innate and T cell-mediated intestinal inflammation

31 March 2020

1 reference

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

31 March 2020

1 reference

Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

31 March 2020

1 reference

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

31 March 2020

1 reference

Anti-interleukin-12 antibody for active Crohn's disease

31 March 2020

1 reference

Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.

31 March 2020

1 reference

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

31 March 2020

1 reference

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

31 March 2020

1 reference

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

31 March 2020

1 reference

Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

31 March 2020

1 reference

Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn?s disease

31 March 2020

1 reference

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

31 March 2020

1 reference

IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.

31 March 2020

1 reference

Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis

31 March 2020

1 reference

Development, cytokine profile and function of human interleukin 17-producing helper T cells

31 March 2020

1 reference

Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease

31 March 2020

1 reference

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

31 March 2020

1 reference

The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

31 March 2020

1 reference

Functional variants of OCTN cation transporter genes are associated with Crohn disease

31 March 2020

1 reference

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

31 March 2020

1 reference

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

31 March 2020

1 reference

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

31 March 2020

1 reference

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

31 March 2020

1 reference

Risk alleles for multiple sclerosis identified by a genomewide study

31 March 2020

1 reference

Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survival

31 March 2020

1 reference

Ulcerative colitis in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survival

31 March 2020

1 reference

Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study

31 March 2020

1 reference

Inflammatory bowel disease in African-American children living in Georgia.

31 March 2020

1 reference

Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking

31 March 2020

1 reference

Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics.

31 March 2020

1 reference

Genetics versus environment in inflammatory bowel disease: results of a British twin study

31 March 2020

1 reference

Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study

31 March 2020

1 reference

Inflammatory bowel disease and domestic hygiene in infancy

31 March 2020

1 reference

Risk of ulcerative colitis among former and current cigarette smokers

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2340

1 reference

release_f247rg3adnbcjjuuaqwftu4baq

18 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f247rg3adnbcjjuuaqwftu4baq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

18500230

1 reference

PubMed ID

18500230