(Q37176000)

English

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

scientific article published on March 2000

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1. (English)

1 reference

Europe PubMed Central

18 August 2017

atherosclerosis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

M Accad

1

1 reference

Europe PubMed Central

18 August 2017

S J Smith

2

1 reference

Europe PubMed Central

18 August 2017

D L Newland

3

1 reference

Europe PubMed Central

18 August 2017

D A Sanan

4

1 reference

Europe PubMed Central

18 August 2017

L E King

5

1 reference

Europe PubMed Central

18 August 2017

M F Linton

6

1 reference

Europe PubMed Central

18 August 2017

S Fazio

7

1 reference

Europe PubMed Central

18 August 2017

R V Farese

8

1 reference

Europe PubMed Central

18 August 2017

language of work or name

0 references

publication date

1 March 2000

1 reference

Europe PubMed Central

18 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

18 August 2017

105

1 reference

Europe PubMed Central

18 August 2017

711-719

1 reference

Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Acyl-coenzyme A:cholesterol acyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Leukocyte low density lipoprotein receptor (LDL-R) does not contribute to LDL clearance in vivo: bone marrow transplantation studies in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

6 September 2017

ACAT inhibitors as antiatherosclerotic agents: compounds and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

14 September 2017

Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

14 September 2017

Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

14 September 2017

Macrophages and atherosclerotic plaque stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

28 September 2017

The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

3 September 2018

Free cholesterol-induced cytotoxicity a possible contributing factor to macrophage foam cell necrosis in advanced atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

3 September 2018

Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

3 September 2018

Apolipoprotein E deficiency leads to cutaneous foam cell formation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=377465

3 September 2018

Serum lipoprotein deficiency in diffuse "normolipemic" plane xanthoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and morphometric evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HL-004, the ACAT inhibitor, prevents the progression of atherosclerosis in cholesterol-fed rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ACAT inhibitor, CI-1011 is effective in the prevention and regression of aortic fatty streak area in hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The spectrum of normolipemic plane xanthoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the alternative pathway of complement by microcrystalline cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of FR145237, a novel ACAT inhibitor, on atherogenesis in cholesterol-fed and WHHL rabbits. Evidence for a direct effect on the arterial wall

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid genotyping of low density lipoprotein receptor knockout mice using a polymerase chain reaction technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727439

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI9021

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

ResearchGate publication ID

0 references

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