(Q37302731)

19 August 2017

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title

Caspases in apoptosis and beyond (English)

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19 August 2017

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J Li

1

1 reference

PubMed ID

18931687

19 August 2017

J Yuan

series ordinal

2

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PubMed ID

18931687

19 August 2017

language of work or name

English

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publication date

1 October 2008

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19 August 2017

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19 August 2017

27

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19 August 2017

6194-6206

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19 August 2017

48

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https://scigraph.springernature.com/pub.10.1038/onc.2008.297

19 August 2017

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cites work

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

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Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis

21 January 2018

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Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

21 January 2018

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Cutting edge: innate immunity conferred by B cells is regulated by caspase-8.

21 January 2018

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Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

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Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

21 January 2018

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A unified model for apical caspase activation

21 January 2018

1 reference

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Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Molecular cloning of the interleukin-1 beta converting enzyme

21 January 2018

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

21 January 2018

1 reference

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

21 January 2018

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p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress

21 January 2018

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Lens fibre cell differentiation - A link with apoptosis?

21 January 2018

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21 January 2018

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Caspase-14 protects against epidermal UVB photodamage and water loss

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-14 reveals its secrets

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Genetic control of programmed cell death in the nematode C. elegans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase 3 activity is required for skeletal muscle differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Is caspase-dependent apoptosis only cell differentiation taken to the extreme?

21 January 2018

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Nod-like proteins in immunity, inflammation and disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

The protein structures that shape caspase activity, specificity, activation and inhibition

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase activity mediates the differentiation of embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Beginnings of a signal-transduction pathway for bioenergetic control of cell survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.297

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FONC.2008.297

Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Apoptosis and caspases regulate death and inflammation in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Prevention of lymphocyte cell death in sepsis improves survival in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

PIDD mediates NF-kappaB activation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-8 serves both apoptotic and nonapoptotic roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

21 January 2018

Death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The CASBAH: a searchable database of caspase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

NLRs join TLRs as innate sensors of pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Inflammatory caspases and inflammasomes: master switches of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Apoptosis in the treatment of cancer: a promise kept?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Structural basis for the activation of human procaspase-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Molecular mechanisms of caspase regulation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase activation: revisiting the induced proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The embryonic cell lineage of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Targeting programmed cell death in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

NAIP and Ipaf control Legionella pneumophila replication in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A genome-wide RNAi screen reveals multiple regulators of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase activation is required for terminal erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspases as therapeutic targets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Caspase-2 mediates neuronal cell death induced by beta-amyloid

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Cell death: the significance of apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.297

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.297

1 reference

19 August 2017

1 reference

PubMed ID

18931687