(Q37323726)

19 August 2017

1 reference

doctoral thesis

1 reference

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507667

30 August 2018

title

Molecular mechanisms of hepatocellular carcinoma (English)

2 references

19 August 2017

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507667

30 August 2018

main subject

hepatocellular carcinoma

1 reference

1 reference

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507667

30 August 2018

author name string

Rajagopal N Aravalli

series ordinal

1

1 reference

19 August 2017

Clifford J Steer

series ordinal

2

1 reference

19 August 2017

Erik N K Cressman

series ordinal

3

1 reference

dissertation submitted to

19 August 2017

University of Leeds

1 reference

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507667

30 August 2018

language of work or name

English

0 references

publication date

1 December 2008

1 reference

19 August 2017

2008

1 reference

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507667

30 August 2018

1 reference

19 August 2017

48

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19 August 2017

2047-2063

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19 August 2017

6

1 reference

Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

19 August 2017

1 reference

7 January 2021

1 reference

7 January 2021

Meta-analysis of studies of occupational exposure to vinyl chloride in relation to cancer mortality.

1 reference

7 January 2021

A case-control study of hepatocellular carcinoma in Osaka, Japan

1 reference

7 January 2021

An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico.

1 reference

7 January 2021

Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women

1 reference

7 January 2021

Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark.

1 reference

7 January 2021

Obesity and diabetes as a risk factor for hepatocellular carcinoma

1 reference

7 January 2021

Coffee and risk of death from hepatocellular carcinoma in a large cohort study in Japan

1 reference

7 January 2021

Oral contraception and the risk of hepatocellular carcinoma

1 reference

7 January 2021

HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence.

1 reference

7 January 2021

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

7 January 2021

Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma

1 reference

7 January 2021

Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas.

1 reference

7 January 2021

Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis

1 reference

7 January 2021

Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection

1 reference

7 January 2021

CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1.

1 reference

7 January 2021

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

1 reference

7 January 2021

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

1 reference

7 January 2021

Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

1 reference

7 January 2021

Strategies for therapeutic targeting of the p53 pathway in cancer.

1 reference

7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

7 January 2021

The role of p53 and pRB in apoptosis and cancer

1 reference

7 January 2021

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1 reference

7 January 2021

p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines

1 reference

7 January 2021

Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases

1 reference

7 January 2021

The retinoblastoma tumor-suppressor gene, the exception that proves the rule

1 reference

7 January 2021

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

1 reference

7 January 2021

To cycle or not to cycle: a critical decision in cancer.

1 reference

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

7 January 2021

RB tumor suppressor gene expression in hepatocellular carcinomas from patients infected with the hepatitis B virus

1 reference

7 January 2021

Disruption of the p16/cyclin D1/retinoblastoma protein pathway in the majority of human hepatocellular carcinomas.

1 reference

7 January 2021

Canonical and alternative MAPK signaling.

1 reference

7 January 2021

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

7 January 2021

Mitogen-activated protein kinases, adherens junction dynamics, and spermatogenesis: a review of recent data

1 reference

7 January 2021

Hepatitis viruses and the MAPK pathway: is this a survival strategy?

1 reference

7 January 2021

Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors

1 reference

7 January 2021

Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors

1 reference

7 January 2021

Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein

1 reference

7 January 2021

Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas

1 reference

7 January 2021

Ha-ras mutations in N-nitrosomorpholine-induced lesions and inhibition of hepatocarcinogenesis by antisense sequences in rat liver

1 reference

7 January 2021

Codon 64 of K-ras gene mutation pattern in hepatocellular carcinomas induced by bleomycin and 1-nitropyrene in A/J mice

1 reference

7 January 2021

Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas

1 reference

7 January 2021

The complexity of Raf-1 regulation

1 reference

7 January 2021

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 reference

7 January 2021

Apoptosis of human BEL-7402 hepatocellular carcinoma cells released by antisense H-ras DNA--in vitro and in vivo studies

1 reference

7 January 2021

Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment

1 reference

7 January 2021

The JAK/STAT signaling pathway

1 reference

7 January 2021

Inhibitors of cytokine signal transduction

1 reference

7 January 2021

Combined hypermethylation and chromosome loss associated with inactivation of SSI-1/SOCS-1/JAB gene in human hepatocellular carcinomas

1 reference

7 January 2021

Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma

1 reference

7 January 2021

Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values

1 reference

7 January 2021

Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis.

1 reference

7 January 2021

Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment.

1 reference

7 January 2021

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis

1 reference

7 January 2021

Anti-TGF-beta strategies for the treatment of chronic liver disease

1 reference

7 January 2021

Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction.

1 reference

7 January 2021

Microenvironmental and cellular consequences of altered blood flow in tumours

1 reference

7 January 2021

Systems biology and new technologies enable predictive and preventative medicine.

1 reference

7 January 2021

The use of high-dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome.

1 reference

7 January 2021

The clinical applications of a systems approach

1 reference

7 January 2021

Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine

1 reference

7 January 2021

Functional genomics of hepatocellular carcinoma

1 reference

7 January 2021

Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver

1 reference

7 January 2021

Review of genetic and epigenetic alterations in hepatocarcinogenesis

1 reference

7 January 2021

Microarray-based analysis for hepatocellular carcinoma: from gene expression profiling to new challenges

1 reference

7 January 2021

Identification of PEG10 as a progression related biomarker for hepatocellular carcinoma

1 reference

7 January 2021

Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas

1 reference

7 January 2021

A tumor progression model for hepatocellular carcinoma: bioinformatic analysis of genomic data.

1 reference

7 January 2021

Molecular profiling of hepatocellular carcinomas by cDNA microarray

1 reference

7 January 2021

Expression profile of nine novel genes differentially expressed in hepatitis B virus-associated hepatocellular carcinomas

1 reference

7 January 2021

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.

1 reference

7 January 2021

Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays

1 reference

7 January 2021

Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C virus-positive patients

1 reference

7 January 2021

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

1 reference

7 January 2021

Gene expression analysis of human hepatocellular carcinoma by using full-length cDNA library

1 reference

7 January 2021

Identification and validation of a novel gene signature associated with the recurrence of human hepatocellular carcinoma

1 reference

7 January 2021

Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease

1 reference

7 January 2021

Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection

1 reference

7 January 2021

Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.

1 reference

7 January 2021

De-regulation of common housekeeping genes in hepatocellular carcinoma

1 reference

7 January 2021

Protein analysis on a proteomic scale

1 reference

7 January 2021

Current two-dimensional electrophoresis technology for proteomics

1 reference

7 January 2021

Mass spectrometry-based "omics" technologies in cancer diagnostics

1 reference

7 January 2021

Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry.

1 reference

7 January 2021

Fluorescent two-dimensional difference gel electrophoresis unveils the potential of gel-based proteomics.

1 reference

7 January 2021

Fluorescence two-dimensional difference gel electrophoresis and mass spectrometry based proteomic analysis of Escherichia coli

1 reference

7 January 2021

The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome

1 reference

7 January 2021

Surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI TOF-MS) and ProteinChip technology in proteomics research

1 reference

7 January 2021

Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues

1 reference

7 January 2021

Profiling protein function with small molecule microarrays

1 reference

7 January 2021

Towards a human proteome atlas: High-throughput generation of mono-specific antibodies for tissue profiling

1 reference

7 January 2021

1 reference

7 January 2021

Proteome chips for whole-organism assays

1 reference

7 January 2021

The 'reverse capture' autoantibody microarray: a native antigen-based platform for autoantibody profiling

1 reference

7 January 2021

Direct analysis of protein complexes using mass spectrometry

1 reference

7 January 2021

Human tissue profiling with multidimensional protein identification technology

1 reference

7 January 2021

Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera.

1 reference

7 January 2021

Identification of specific protein markers in microdissected hepatocellular carcinoma

1 reference

7 January 2021

Early diagnostic potential for hepatocellular carcinoma using the SELDI ProteinChip system

1 reference

7 January 2021

Identification of human hepatocellular carcinoma-related proteins by proteomic approaches

1 reference

7 January 2021

Proteomic profiling of proteins decreased in hepatocellular carcinoma from patients infected with hepatitis C virus

1 reference

7 January 2021

Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein

1 reference

7 January 2021

Modification of host lipid raft proteome upon hepatitis C virus replication

1 reference

7 January 2021

Strategic shotgun proteomics approach for efficient construction of an expression map of targeted protein families in hepatoma cell lines

1 reference

7 January 2021

Identification of differentially expressed proteins between human hepatoma and normal liver cell lines by two-dimensional electrophoresis and liquid chromatography-ion trap mass spectrometry

1 reference

7 January 2021

Proteomic analysis of differential protein expression in a human hepatoma revertant cell line by using an improved two-dimensional electrophoresis procedure combined with matrix assisted laser desorption/ionization-time of flight-mass spectrometry

1 reference

7 January 2021

Expression of tumor-associated protein variants in chemically induced rat hepatomas and transformed rat liver cell lines determined by two-dimensional electrophoresis

1 reference

7 January 2021

Differential proteomic analysis of human hepatocellular carcinoma cell line metastasis-associated proteins

1 reference

7 January 2021

Proteome analysis of hepatocellular carcinoma cell strains, MHCC97-H and MHCC97-L, with different metastasis potentials

1 reference

7 January 2021

Metabolomics by numbers: acquiring and understanding global metabolite data

1 reference

7 January 2021

Metabolomics reviewed: a new "omics" platform technology for systems biology and implications for natural products research.

1 reference

7 January 2021

High-throughput tissue extraction protocol for NMR- and MS-based metabolomics

1 reference

7 January 2021

A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics

1 reference

7 January 2021

Peptide mapping of proteins in human body fluids using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

1 reference

7 January 2021

Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization.

1 reference

7 January 2021

Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C.

1 reference

7 January 2021

Proteome analysis of human hepatocellular carcinoma tissues by two-dimensional difference gel electrophoresis and mass spectrometry.

1 reference

7 January 2021

Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers.

1 reference

7 January 2021

Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression

1 reference

7 January 2021

1 reference

7 January 2021

Applying the principles of stem-cell biology to cancer

1 reference

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

7 January 2021

Cancerous stem cells can arise from pediatric brain tumors

1 reference

7 January 2021

Identification of human brain tumour initiating cells

1 reference

7 January 2021

Prospective identification of tumorigenic prostate cancer stem cells

1 reference

7 January 2021

Prospective identification of tumorigenic breast cancer cells

1 reference

7 January 2021

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 reference

7 January 2021

Gastric cancer originating from bone marrow-derived cells

1 reference

7 January 2021

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

1 reference

7 January 2021

Identification and expansion of human colon-cancer-initiating cells

1 reference

7 January 2021

Identification of bronchioalveolar stem cells in normal lung and lung cancer

1 reference

7 January 2021

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

1 reference

7 January 2021

Hepatic progenitor cells in human fetal liver express the oval cell marker Thy-1

1 reference

7 January 2021

Heterogeneity of the "oval-cell" response in the hamster liver during cholangiocarcinogenesis following Clonorchis sinensis infection and dimethylnitrosamine treatment

1 reference

7 January 2021

Hepatic precursors derived from murine embryonic stem cells contribute to regeneration of injured liver.

1 reference

7 January 2021

Immortalization of a primate bipotent epithelial liver stem cell

1 reference

7 January 2021

Hepatic maturation in differentiating embryonic stem cells in vitro

1 reference

7 January 2021

Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes

1 reference

7 January 2021

In vitro hepatic differentiation of human mesenchymal stem cells

1 reference

7 January 2021

In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.

1 reference

7 January 2021

Hepatocytes from non-hepatic adult stem cells

1 reference

7 January 2021

Liver from bone marrow in humans.

1 reference

7 January 2021

Isolation, culture, and transplantation of intrahepatic biliary epithelial cells and oval cells

1 reference

7 January 2021

Bone marrow as a potential source of hepatic oval cells

1 reference

7 January 2021

Cell fusion is the principal source of bone-marrow-derived hepatocytes

1 reference

7 January 2021

Bone marrow progenitors are not the source of expanding oval cells in injured liver

1 reference

7 January 2021

Oval cell numbers in human chronic liver diseases are directly related to disease severity.

1 reference

7 January 2021

Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver

1 reference

7 January 2021

Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma

1 reference

7 January 2021

Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes

1 reference

7 January 2021

Origin and characterization of a human bipotent liver progenitor cell line

1 reference

7 January 2021

Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver

1 reference

7 January 2021

RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse

1 reference

7 January 2021

Identification of novel genes coding for small expressed RNAs

1 reference

7 January 2021

1 reference

7 January 2021

microRNAs: small molecules with big roles - C. elegans to human cancer

1 reference

7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

7 January 2021

A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes

1 reference

7 January 2021

Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications

1 reference

7 January 2021

The guardian's little helper: microRNAs in the p53 tumor suppressor network

1 reference

7 January 2021

miRNA genetic alterations in human cancers

1 reference

7 January 2021

MicroRNAs and cell cycle regulation

1 reference

7 January 2021

The let-7 microRNA represses cell proliferation pathways in human cells

1 reference

7 January 2021

MicroRNA signatures in human cancers

1 reference

7 January 2021

miR-122, a paradigm for the role of microRNAs in the liver

1 reference

7 January 2021

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

1 reference

7 January 2021

Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma

1 reference

7 January 2021

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

1 reference

7 January 2021

Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas.

1 reference

7 January 2021

Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival.

1 reference

7 January 2021

Identification of metastasis-related microRNAs in hepatocellular carcinoma.

1 reference

7 January 2021

Molecular pathways and related target therapies in liver carcinoma.

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.22580

1 reference

19 August 2017

0 references

1 reference