(Q37333610)

19 August 2017

1 reference

title

Polarity proteins in migration and invasion (English)

1 reference

19 August 2017

S Etienne-Manneville

1

1 reference

PubMed ID

19029938

19 August 2017

language of work or name

English

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publication date

1 November 2008

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19 August 2017

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19 August 2017

27

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19 August 2017

6970-6980

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19 August 2017

55

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https://scigraph.springernature.com/pub.10.1038/onc.2008.347

19 August 2017

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cites work

Bazooka is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia.

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LKB1-dependent signaling pathways

31 March 2020

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A role for Cdc42 in macrophage chemotaxis

31 March 2020

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Par complex in cancer: a regulator of normal cell polarity joins the dark side

31 March 2020

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Polarity complex proteins

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Role of adenomatous polyposis coli (APC) and microtubules in directional cell migration and neuronal polarization

31 March 2020

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

31 March 2020

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Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Integrated activity of PDZ protein complexes regulates epithelial polarity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Multitasking in tumor progression: signaling functions of cell adhesion molecules.

31 March 2020

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Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy.

31 March 2020

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Big roles for small GTPases in the control of directed cell movement

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

MAP kinase signalling pathways in cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

31 March 2020

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Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Actin and microtubules in cell motility: which one is in control?

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Cdc42--the centre of polarity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

31 March 2020

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Rho GTPases in cell biology

31 March 2020

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

31 March 2020

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Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Prespecification and plasticity: shifting mechanisms of cell migration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Tumour-cell invasion and migration: diversity and escape mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

The PAR proteins: fundamental players in animal cell polarization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Epithelial-mesenchymal transition and tumour invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Role of aPKC Isoforms and Their Binding Partners Par3 and Par6 in Epidermal Barrier Formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The molecular basis and clinical aspects of Peutz-Jeghers syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.347

Wnt/beta-catenin signaling: new (and old) players and new insights

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The Scribble and Par complexes in polarity and migration: friends or foes?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Identification of genes required for cytoplasmic localization in early C. elegans embryos

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The regulation of cell motility and chemotaxis by phospholipid signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Metastasis: cell-autonomous mechanisms versus contributions by the tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Mechanisms regulating epithelial stratification

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Expression of Hugl-1 is strongly reduced in malignant melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The Wnt signaling pathway in development and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Tiam1 takes PARt in cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

A Genetic Screen in Drosophila for Metastatic Behavior

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

A causal role for E-cadherin in the transition from adenoma to carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Requirement for Par-6 and Bazooka in Drosophila border cell migration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The intestinal epithelial stem cell: the mucosal governor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Cell migration: integrating signals from front to back

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Mechanisms of cancer cell invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Colorectal cancer and genetic alterations in the Wnt pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

LKB1/STRAD promotes axon initiation during neuronal polarization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

PATJ regulates directional migration of mammalian epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Microtubule-induced cortical cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Evolution of the mechanisms that establish the embryonic axes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Modeling transformation and metastasis in Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Linking epithelial-mesenchymal transition to the well-known polarity protein Par6

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Human papillomaviruses, cervical cancer and cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Apical junctional complexes and cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Cell polarity in development and cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

Dishevelled promotes axon differentiation by regulating atypical protein kinase C.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.347

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.347

1 reference

19 August 2017

1 reference

PubMed ID

19029938