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PI 3-kinase and cancer: changing accents
scientific article published on February 2009
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scholarly article
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Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
review article
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stated in
Europe PubMed Central
title
PI 3-kinase and cancer: changing accents
(English)
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stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
author
Jonathan Ross Hart
object named as
Jonathan R Hart
series ordinal
3
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Peter K. Vogt
object named as
Peter K Vogt
series ordinal
1
0 references
author name string
Marco Gymnopoulos
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
publication date
1 February 2009
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stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
published in
Current Opinion in Genetics & Development
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stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
volume
19
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stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
page(s)
12-17
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stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
cites work
The PTEN-PI3K pathway: of feedbacks and cross-talks
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PubMed Central
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6 September 2017
PI3K pathway alterations in cancer: variations on a theme
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PubMed Central
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6 September 2017
The role of PTEN signaling perturbations in cancer and in targeted therapy
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PubMed Central
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6 September 2017
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development
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PubMed Central
reference URL
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6 September 2017
PTEN-deficient cancers depend on PIK3CB.
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PubMed Central
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6 September 2017
Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis
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6 September 2017
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.
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PubMed Central
reference URL
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6 September 2017
Tenets of PTEN tumor suppression
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PubMed Central
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6 September 2017
Insights into the oncogenic effects of PIK3CA mutations from the structure of p110alpha/p85alpha
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PubMed Central
reference URL
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6 September 2017
Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms
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PubMed Central
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6 September 2017
Targeting phosphoinositide 3-kinase: moving towards therapy
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PubMed Central
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6 September 2017
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
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6 September 2017
Rare cancer-specific mutations in PIK3CA show gain of function
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PubMed Central
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6 September 2017
PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?
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PubMed Central
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6 September 2017
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
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PubMed Central
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6 September 2017
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Cancer-specific mutations in PIK3CA are oncogenic in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
6 September 2017
High frequency of mutations of the PIK3CA gene in human cancers
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
6 September 2017
Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
6 September 2017
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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6 September 2017
Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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14 September 2017
Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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14 September 2017
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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14 September 2017
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
28 September 2017
Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
26 June 2018
Functional inhibition of PI3K by the betaGBP molecule suppresses Ras-MAPK signalling to block cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
26 June 2018
Functional analysis of PIK3CA gene mutations in human colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
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26 June 2018
SnapShot: PTEN signaling pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
2 September 2018
Oncogenic signaling of class I PI3K isoforms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
2 September 2018
Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
2 October 2018
Essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746202
retrieved
3 December 2018
A selective inhibitor of the p110delta isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19185485
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.GDE.2008.11.011
1 reference
stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
PMCID
2746202
1 reference
stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
PubMed ID
19185485
1 reference
stated in
Europe PubMed Central
PMCID
2746202
retrieved
19 August 2017
ResearchGate publication ID
23967211
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