(Q37401016)

English

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

scientific article published on December 2009

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scholarly article

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7 February 2020

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1) (English)

1 reference

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7 February 2020

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David Tai Leong

4

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7 February 2020

Andre J van Wijnen

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Andre J van Wijnen

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7 February 2020

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Gary S Stein

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7 February 2020

Mario A Galindo

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Mario Galindo

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7 February 2020

11

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Simon M Cool

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7 February 2020

Saminathan Suresh Nathan

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Saminathan S Nathan

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7 February 2020

Barry P Pereira

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object named as

Barry P Pereira

1 reference

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7 February 2020

Manuel Salto-Tellez

9

object named as

Manuel Salto-Tellez

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7 February 2020

author name string

Yefang Zhou

2

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7 February 2020

Anurag Gupta

3

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7 February 2020

Khin Zarchi Aung

5

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7 February 2020

Ling Ling

6

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7 February 2020

Robert W H Pho

7

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7 February 2020

publication date

1 December 2009

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7 February 2020

Journal of Cellular Physiology

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7 February 2020

221

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7 February 2020

778-788

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7 February 2020

3

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7 February 2020

describes a project that uses

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Intercellular transfer to signalling endosomes regulates an ex vivo bone marrow niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Ethnic disparities in Americans of European descent versus Americans of African descent related to polymorphic ERCC1, ERCC2, XRCC1, and PARP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Tumor interstitial fluid pressure may regulate angiogenic factors in osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

The retinoblastoma protein in osteoblast differentiation and osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Elevated physiologic tumor pressure promotes proliferation and chemosensitivity in human osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Treatment effects in pediatric soft tissue and bone tumors: practical considerations for the pathologist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Effect of TNF-alpha on human osteosarcoma cell line Saos2--TNF-alpha regulation of bone sialoprotein gene expression in Saos2 osteoblast-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Superior survival in treatment of primary nonmetastatic pediatric osteosarcoma of the extremity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Basic fibroblast growth factor autocrine loop controls human osteosarcoma phenotyping and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Etiology of osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Ethnic group and survival from childhood cancer: report from the UK Children's Cancer Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Risk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

6 September 2017

Trends and variability in survival from osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

14 September 2017

Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

26 June 2018

The role of RB in cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

26 June 2018

Adjuvant chemotherapy of high-grade osteosarcoma of the extremity. Updated results of the Multi-Institutional Osteosarcoma Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

26 June 2018

Inactivation of p53 gene in human and murine osteosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

26 June 2018

Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.

1 reference

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2 September 2018

Treatment algorithm for locally recurrent osteosarcoma based on local disease-free interval and the presence of lung metastasis.

1 reference

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2 September 2018

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

2 September 2018

UV-induced DNA damage and melanin content in human skin differing in racial/ethnic origin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

2 September 2018

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768260

2 September 2018

Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preoperative chemotherapy for osteosarcoma with intravenous adriamycin and intra-arterial cis-platinum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International variations in the incidence of childhood bone tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human solid tumors: cytogenetic techniques

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrum of bone tumors in Chiang Mai University Hospital, Thailand according to WHO classification 2002: A study of 1,001 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial osteosarcoma associated with 13;14 chromosomal rearrangement

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surgical outcomes in osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19746444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JCP.21921

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Europe PubMed Central

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7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19746444%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19746444%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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