(Q37401076)

20 August 2017

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting (English)

1 reference

20 August 2017

0 references

1 reference

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Wesley Cai

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Qin Yan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

7

Molly Gale

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Lizhen Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Shang-Min Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Min Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

William K C Cheung

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Qi Xu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

25 July 2016

1 reference

20 August 2017

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

e149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 June 2020

copyright license

start time

13 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5100567/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance

1 reference

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Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

6 September 2017

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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

6 September 2017

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Rationally engineered Cas9 nucleases with improved specificity

6 September 2017

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Crystal Structure of Staphylococcus aureus Cas9

6 September 2017

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Rapid and efficient one-step generation of paired gRNA CRISPR-Cas9 libraries

6 September 2017

1 reference

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Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9

6 September 2017

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Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs

6 September 2017

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Small molecule-triggered Cas9 protein with improved genome-editing specificity

6 September 2017

1 reference

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Somatic CRISPR-Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia

6 September 2017

1 reference

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A versatile modular vector system for rapid combinatorial mammalian genetics

6 September 2017

1 reference

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Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system.

6 September 2017

1 reference

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An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo

6 September 2017

1 reference

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Rational design of a split-Cas9 enzyme complex

6 September 2017

1 reference

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Inducible in vivo genome editing with CRISPR-Cas9

6 September 2017

1 reference

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A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

6 September 2017

1 reference

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A split-Cas9 architecture for inducible genome editing and transcription modulation

6 September 2017

1 reference

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CRISPR-Cas9-based photoactivatable transcription system.

6 September 2017

1 reference

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Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans

6 September 2017

1 reference

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Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

6 September 2017

1 reference

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The iCRISPR platform for rapid genome editing in human pluripotent stem cells

6 September 2017

1 reference

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Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice

6 September 2017

1 reference

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Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

6 September 2017

1 reference

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Improved vectors and genome-wide libraries for CRISPR screening

6 September 2017

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An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells

6 September 2017

1 reference

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Development and applications of CRISPR-Cas9 for genome engineering

6 September 2017

1 reference

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CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

6 September 2017

1 reference

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

6 September 2017

1 reference

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

6 September 2017

1 reference

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Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

6 September 2017

1 reference

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Genetic screens in human cells using the CRISPR-Cas9 system

6 September 2017

1 reference

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Genome engineering using the CRISPR-Cas9 system

6 September 2017

1 reference

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 September 2017

1 reference

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

DNA targeting specificity of RNA-guided Cas9 nucleases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

RNA-guided human genome engineering via Cas9

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Multiplex genome engineering using CRISPR/Cas systems

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

A one pot, one step, precision cloning method with high throughput capability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

The diverse functions of histone lysine methylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5100567

2 September 2018

Identifiers

DOI

10.1093/NAR/GKW660

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27458201%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

27458201

1 reference