(Q37455222)

English

Downstream mediators of the intratumoral interferon response suppress antitumor immunity, induce gemcitabine resistance and associate with poor survival in human pancreatic cancer.

scientific article published on 30 September 2015

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scholarly article

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25 February 2020

Downstream mediators of the intratumoral interferon response suppress antitumor immunity, induce gemcitabine resistance and associate with poor survival in human pancreatic cancer (English)

1 reference

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25 February 2020

Thomas J George

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25 February 2020

Lyle L Moldawer

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object named as

Lyle L Moldawer

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25 February 2020

author name string

Daniel Delitto

1

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25 February 2020

Chelsey Perez

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25 February 2020

Song Han

3

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25 February 2020

David H Gonzalo

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25 February 2020

Kien Pham

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25 February 2020

Andrea E Knowlton

6

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25 February 2020

Christina L Graves

7

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25 February 2020

Kevin E Behrns

8

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25 February 2020

Ryan M Thomas

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25 February 2020

Chen Liu

11

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25 February 2020

Jose G Trevino

13

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25 February 2020

Shannon M Wallet

14

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25 February 2020

Steven J Hughes

15

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25 February 2020

publication date

30 September 2015

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25 February 2020

Cancer Immunology, Immunotherapy

1 reference

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25 February 2020

64

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25 February 2020

1553-1563

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25 February 2020

12

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25 February 2020

https://scigraph.springernature.com/pub.10.1007/s00262-015-1760-y

0 references

Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6C(low) F4/80(+) Extratumoral Macrophages

1 reference

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23 August 2017

In vitro Production of IL-6 and IFN-γ is Influenced by Dietary Variables and Predicts Upper Respiratory Tract Infection Incidence and Severity Respectively in Young Adults

1 reference

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Patient-derived xenograft models for pancreatic adenocarcinoma demonstrate retention of tumor morphology through incorporation of murine stromal elements

1 reference

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Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma

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23 August 2017

Desmoplasia and chemoresistance in pancreatic cancer

1 reference

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23 August 2017

Gemcitabine: metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer

1 reference

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Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

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23 August 2017

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

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23 August 2017

Selective disruption of rb-raf-1 kinase interaction inhibits pancreatic adenocarcinoma growth irrespective of gemcitabine sensitivity

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Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma

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Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

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23 August 2017

Activation of toll-like receptor 2 prevents suppression of T-cell interferon γ production by modulating p38/extracellular signal-regulated kinase pathways following alcohol and burn injury

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Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

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Cancer as an overhealing wound: an old hypothesis revisited

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Pancreatic cancer microenvironment

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Immunotherapy for pancreatic cancer - science driving clinical progress

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Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients

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PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

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In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

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Stromal biology and therapy in pancreatic cancer: a changing paradigm

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Pancreatic cancer: The microenvironment needs attention too!

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IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival.

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Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

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12 December 2020

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00262-015-1760-Y

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26423423%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

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25 February 2020

1 reference

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25 February 2020

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