(Q37462172)

20 August 2017

1 reference

title

Obesity, inflammation, and atherosclerosis (English)

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20 August 2017

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2

Peter Libby

1 reference

20 August 2017

Viviane Z Rocha

1

1 reference

PubMed ID

19399028

20 August 2017

language of work or name

English

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publication date

28 April 2009

1 reference

Nature Reviews Cardiology

20 August 2017

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20 August 2017

6

1 reference

20 August 2017

399-409

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20 August 2017

6

1 reference

Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis

20 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Macrophage heterogeneity and tissue lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adiponectin: a key adipocytokine in metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events (CARE) Investigators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

A potential decline in life expectancy in the United States in the 21st century

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Atherosclerosis — An Inflammatory Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammation and metabolic disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Hyperlipidemia and atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part IV: the 1984 coronary primary prevention trial ends it--almost

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Role of oxidized low density lipoprotein in atherogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammation in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Insulin sensitivity: modulation by nutrients and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

TLR4 links innate immunity and fatty acid-induced insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Innate immune recognition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part I

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part II: the early evidence linking hypercholesterolemia to coronary disease in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Thematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Ccr5 But Not Ccr1 Deficiency Reduces Development of Diet-Induced Atherosclerosis in Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The multiple facets of the fat tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected].

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The immune response in atherosclerosis: a double-edged sword

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammation, atherosclerosis, and coronary artery disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Alternative activation of macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inhibition of endothelial cell proliferation by gamma-interferon

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Azithromycin for the secondary prevention of coronary events

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Natural regulatory T cells control the development of atherosclerosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Progression of atheroma: a struggle between death and procreation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

A central role for JNK in obesity and insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

IKK-beta links inflammation to obesity-induced insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Mechanisms linking obesity with cardiovascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein modulates risk prediction based on the Framingham Score: implications for future risk assessment: results from a large cohort study in southern Germany

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inflammatory markers and the risk of coronary heart disease in men and women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein in the prediction of cardiovascular and overall mortality in middle-aged men: a population-based cohort study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Elevated C-reactive protein levels in overweight and obese adults

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

31 March 2020

12 December 2020

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adiposity and cardiovascular disorders: disturbance of the regulatory system consisting of humoral and neuronal signals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adipose tissue, inflammation, and cardiovascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Adiponectin: action, regulation and association to insulin sensitivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

C-reactive protein levels and outcomes after statin therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The effects of rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, on markers of endothelial cell activation, C-reactive protein, and fibrinogen levels in non-diabetic coronary artery disease patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control: results from the pioneer study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Direct antiatherosclerotic effects of PPAR agonists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Salsalate improves glycemia and inflammatory parameters in obese young adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Atherosclerosis--an immune disease: The Anitschkov Lecture 2007.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Chemokines as potential therapeutic targets in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

A Novel RANTES Antagonist Prevents Progression of Established Atherosclerotic Lesions in Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.55

31 March 2020

1 reference

12 December 2020

1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo.

1 reference

PubMed

12 December 2020

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/NRCARDIO.2009.55

1 reference

20 August 2017

1 reference

PubMed ID

19399028