(Q37462360)

20 August 2017

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title

The mammalian family of sterile 20p-like protein kinases (English)

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20 August 2017

Eric Delpire

1

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20 August 2017

28 April 2009

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20 August 2017

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20 August 2017

458

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20 August 2017

953-967

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20 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s00424-009-0674-y

20 August 2017

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cites work

A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0674-Y

The Drosophila Sterile-20 Kinase Slik Controls Cell Proliferation and Apoptosis during Imaginal Disc Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0674-Y

Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0674-Y

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0674-Y

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

21 January 2018

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12 December 2020

Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

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12 December 2020

A single pair of acidic residues in the kinase major groove mediates strong substrate preference for P-2 or P-5 arginine in the AGC, CAMK, and STE kinase families

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12 December 2020

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

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12 December 2020

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

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12 December 2020

A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome

1 reference

12 December 2020

Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculus

1 reference

12 December 2020

The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton

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12 December 2020

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

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12 December 2020

kin-18, a C. elegans protein kinase involved in feeding

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12 December 2020

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

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12 December 2020

Identification of an autoinhibitory domain of p21-activated protein kinase 5.

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12 December 2020

Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3

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12 December 2020

Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase

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12 December 2020

Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2

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12 December 2020

PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)

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12 December 2020

Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment.

1 reference

12 December 2020

The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes.

1 reference

12 December 2020

Emerging from the Pak: the p21-activated protein kinase family.

1 reference

12 December 2020

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

1 reference

12 December 2020

Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia

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12 December 2020

MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway

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12 December 2020

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

1 reference

12 December 2020

Cloning and characterization of a member of the MST subfamily of Ste20-like kinases

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12 December 2020

3q29 microdeletion syndrome: clinical and molecular characterization of a new syndrome

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12 December 2020

Structural insights into the recognition of substrates and activators by the OSR1 kinase

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12 December 2020

PAK3 mutation in nonsyndromic X-linked mental retardation

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12 December 2020

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

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12 December 2020

LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytes

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12 December 2020

GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channel

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12 December 2020

Cloning and chromosomal localization of a human class III myosin

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12 December 2020

The Ste20 kinase MST4 plays a role in prostate cancer progression

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12 December 2020

The kinase domain alters the kinetic properties of the myosin IIIA motor

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12 December 2020

Human TAO kinase 1 induces apoptosis in SH-SY5Y cells

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12 December 2020

Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38.

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12 December 2020

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20

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12 December 2020

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion

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12 December 2020

Induction of apoptosis by SLK, a Ste20-related kinase

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12 December 2020

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

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12 December 2020

Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I.

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12 December 2020

Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans.

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12 December 2020

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

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12 December 2020

Crystal structure of domain-swapped STE20 OSR1 kinase domain

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12 December 2020

Determination of human myosin III as a motor protein having a protein kinase activity

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12 December 2020

The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai

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12 December 2020

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12 December 2020

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

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12 December 2020

The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain

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12 December 2020

Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades

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12 December 2020

A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression

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12 December 2020

Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation

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12 December 2020

Lats2 is a negative regulator of myocyte size in the heart

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12 December 2020

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

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12 December 2020

p21-activated kinases in cancer

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12 December 2020

From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30

1 reference

12 December 2020

Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.

1 reference

12 December 2020

Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family

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12 December 2020

dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade

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12 December 2020

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling

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12 December 2020

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

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12 December 2020

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

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12 December 2020

Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements

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12 December 2020

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

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12 December 2020

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12 December 2020

Targeted disruption of the gene for the PAK5 kinase in mice

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12 December 2020

Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis.

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12 December 2020

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway

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12 December 2020

A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans

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12 December 2020

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

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12 December 2020

Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center

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12 December 2020

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

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12 December 2020

A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase

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12 December 2020

SPAK and OSR1, key kinases involved in the regulation of chloride transport

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12 December 2020

Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase

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12 December 2020

Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38

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12 December 2020

Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K

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12 December 2020

Biology of the p21-activated kinases

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12 December 2020

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

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12 December 2020

From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.

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12 December 2020

Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor

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12 December 2020

Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1).

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12 December 2020

Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

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12 December 2020

The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability

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12 December 2020

Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase

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12 December 2020

Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

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12 December 2020

Light-dependent translocation of visual arrestin regulated by the NINAC myosin III.

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12 December 2020

TAO kinases mediate activation of p38 in response to DNA damage

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12 December 2020

Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties

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12 December 2020

Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region

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12 December 2020

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

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12 December 2020

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12 December 2020

Cloning and characterization of a human protein kinase with homology to Ste20

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12 December 2020

Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase

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12 December 2020

Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3.

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12 December 2020

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)

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12 December 2020

v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II.

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12 December 2020

Genome-wide analysis of SPAK/OSR1 binding motifs

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12 December 2020

Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter

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12 December 2020

Regulation of protein kinases; controlling activity through activation segment conformation

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12 December 2020

Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes

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12 December 2020

NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis

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12 December 2020

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

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12 December 2020

Cloning and characterization of MST4, a novel Ste20-like kinase

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12 December 2020

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

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12 December 2020

Identification of regulatory phosphorylation sites in a cell volume- and Ste20 kinase-dependent ClC anion channel

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12 December 2020

Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue

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12 December 2020

A functional genomic analysis of cell morphology using RNA interference

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12 December 2020

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

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12 December 2020

Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain

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12 December 2020

p21-activated kinases: three more join the Pak.

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12 December 2020

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

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12 December 2020

X-linked mild non-syndromic mental retardation with neuropsychiatric problems and the missense mutation A365E in PAK3.

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12 December 2020

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

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12 December 2020

Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development

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12 December 2020

Biosignaling of mammalian Ste20-related kinases

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12 December 2020

Kinetic and catalytic mechanisms of protein kinases

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12 December 2020

Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.

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12 December 2020

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

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12 December 2020

Biochemical analysis of MST1 kinase: elucidation of a C-terminal regulatory region

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12 December 2020

Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6

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12 December 2020

The Ste20 group kinases as regulators of MAP kinase cascades

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12 December 2020

10.1007/S00424-009-0674-Y

Identifiers

DOI

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20 August 2017

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PubMed ID

19399514