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English
Cytoplasmic functions of the tumour suppressor p53.
scientific article published on April 2009
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Cytoplasmic functions of the tumour suppressor p53.
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
author
Guido Kroemer
series ordinal
2
object named as
Guido Kroemer
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Douglas R. Green
object named as
Douglas R Green
series ordinal
1
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language of work or name
English
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publication date
1 April 2009
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
published in
Nature
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
volume
458
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
page(s)
1127-1130
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
issue
7242
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/nature07986
0 references
cites work
ARF induces autophagy by virtue of interaction with Bcl-xl.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
BAX activation is initiated at a novel interaction site
1 reference
stated in
PubMed Central
reference URL
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retrieved
23 August 2017
A complex barcode underlies the heterogeneous response of p53 to stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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23 August 2017
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.
1 reference
stated in
PubMed Central
reference URL
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23 August 2017
Regulation of autophagy by cytoplasmic p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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23 August 2017
Transcriptional control of human p53-regulated genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
1 reference
stated in
PubMed Central
reference URL
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23 August 2017
Negative regulation of the deacetylase SIRT1 by DBC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence
1 reference
stated in
PubMed Central
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Diagnosing and exploiting cancer's addiction to blocks in apoptosis
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23 August 2017
Autophagy in the Pathogenesis of Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Regulation of p53 tetramerization and nuclear export by ARC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Role of autophagy in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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23 August 2017
The common biology of cancer and ageing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Monoubiquitylation promotes mitochondrial p53 translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Mitochondrial membrane permeabilization in cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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23 August 2017
p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
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23 August 2017
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
p53 has a direct apoptogenic role at the mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
23 August 2017
Mitochondrial translocation of p53 underlies the selective death of hippocampal CA1 neurons after global cerebral ischaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
14 September 2017
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
14 September 2017
The N-terminal domain of tumor suppressor p53 is involved in the molecular interaction with the anti-apoptotic protein Bcl-Xl.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
14 September 2017
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
28 September 2017
Mutant p53 protein localized in the cytoplasm inhibits autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 September 2018
Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 September 2018
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 September 2018
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 September 2018
Induction of apoptosis in HeLa cells by trans-activation-deficient p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 September 2018
The effects of p53 on whole organism longevity are mediated by autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814168
retrieved
2 October 2018
Lack of correlation between p53-dependent transcriptional activity and the ability to induce apoptosis among 179 mutant p53s
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19407794
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NATURE07986
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
Dimensions Publication ID
1023842690
0 references
PMCID
2814168
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
PubMed ID
19407794
1 reference
stated in
Europe PubMed Central
PMCID
2814168
retrieved
20 August 2017
ResearchGate publication ID
24394688
0 references
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