Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37576214)
Watch
English
Aberrant islet unfolded protein response in type 2 diabetes
scientific article published on 11 February 2014
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
title
Aberrant islet unfolded protein response in type 2 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
main subject
type 2 diabetes
0 references
author
Feyza Engin
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Alena Yermalovich
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Gökhan Hotamışlıgil
series ordinal
4
object named as
Gökhan S Hotamisligil
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author name string
Truc Nguyen
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
language of work or name
English
0 references
publication date
11 February 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
published in
Scientific Reports
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
volume
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
page(s)
4054
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
copyright license
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
start time
11 February 2014
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
The role of adipocyte XBP1 in metabolic regulation during lactation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
The unfolded protein response: from stress pathway to homeostatic regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress in the β-cell pathogenesis of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
ER stress in pancreatic beta cells: the thin red line between adaptation and failure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Proinsulin and the genetics of diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Islet beta cell failure in type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Wolcott-Rallison Syndrome: clinical, genetic, and functional study of EIF2AK3 mutations and suggestion of genetic heterogeneity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
23 August 2017
Endoplasmic reticulum stress and pancreatic β-cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
6 September 2017
A Longitudinal Hormonal Profile of the Genetically Obese Mouse*
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
6 September 2017
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
14 September 2017
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
14 September 2017
Immunoreactive glucagon levels in obese-hyperglycemic (ob/ob) mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
25 June 2018
Studies on serum lipids, insulin, and glucagon and on muscle triglyceride in rats adapted to high-fat and high-carbohydrate diets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
25 June 2018
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Glucose modulation of insulin and glucagon secretion is altered in impaired glucose tolerance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Age-related changes in lipid and carbohydrate metabolism of the genetically obese mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920274
retrieved
1 September 2018
Identifiers
DOI
10.1038/SREP04054
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMC publication ID
3920274
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed publication ID
24514745
1 reference
stated in
Europe PubMed Central
PMC publication ID
3920274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24514745%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
ResearchGate publication ID
260153334
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit