(Q37594580)

21 August 2017

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title

Molecular networks as sensors and drivers of common human diseases (English)

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21 August 2017

Eric E Schadt

1

1 reference

PubMed ID

19741703

21 August 2017

language of work or name

English

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publication date

1 September 2009

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21 August 2017

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21 August 2017

461

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21 August 2017

218-223

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21 August 2017

7261

1 reference

https://scigraph.springernature.com/pub.10.1038/nature08454

21 August 2017

0 references

cites work

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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

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12 December 2020

RNA-Seq: a revolutionary tool for transcriptomics

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Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

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Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

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Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids

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12 December 2020

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

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12 December 2020

A common genetic risk factor for colorectal and prostate cancer

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12 December 2020

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

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Evidence for dynamically organized modularity in the yeast protein-protein interaction network

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Integrative genomics and drug development

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Distilling free-form natural laws from experimental data

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Genomics and biology come together to fight HIV.

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Genomewide association studies and human disease

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Common polymorphic transcript variation in human disease

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An integrated genomic analysis of human glioblastoma multiforme

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Towards a proteome-scale map of the human protein–protein interaction network

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Genetics of gene expression surveyed in maize, mouse and man

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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

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12 December 2020

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

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12 December 2020

Genetic analysis of radiation-induced changes in human gene expression

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12 December 2020

Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

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12 December 2020

Mapping the genetic architecture of gene expression in human liver

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Genetic basis of proteome variation in yeast

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A network view of disease and compound screening

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Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

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Genetic mapping in human disease

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An integrative genomics approach to the reconstruction of gene networks in segregating populations.

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Real-time DNA sequencing from single polymerase molecules

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12 December 2020

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

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12 December 2020

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

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12 December 2020

Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

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Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study

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Multiple regions within 8q24 independently affect risk for prostate cancer

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

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Genetic risk prediction--are we there yet?

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Embracing complexity, inching closer to reality

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Genetic inheritance of gene expression in human cell lines

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Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

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12 December 2020

Genomic analysis of metabolic pathway gene expression in mice

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12 December 2020

Common genetic variation and human traits

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12 December 2020

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

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12 December 2020

Genetic analysis of genome-wide variation in human gene expression

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12 December 2020

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

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12 December 2020

Adipose tissue macrophages.

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12 December 2020

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

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12 December 2020

Integrating genetic and network analysis to characterize genes related to mouse weight

1 reference

12 December 2020

Variations in DNA elucidate molecular networks that cause disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08454

7 January 2021

inferred from DOI database lookup

Genetics of gene expression and its effect on disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08454

7 January 2021

inferred from DOI database lookup

An integrative genomics approach to infer causal associations between gene expression and disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08454

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE08454

1 reference

PubMed ID

19741703

Dimensions Publication ID

21 August 2017

0 references

1 reference

PubMed ID

19741703