(Q37628447)

21 August 2017

1 reference

title

Regulation of death receptor signaling by the ubiquitin system (English)

1 reference

21 August 2017

I E Wertz

1

1 reference

PubMed ID

19893571

21 August 2017

V M Dixit

series ordinal

2

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21 August 2017

1 January 2010

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Cell Death & Differentiation

21 August 2017

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21 August 2017

17

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21 August 2017

14-24

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21 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/cdd.2009.168

21 August 2017

0 references

cites work

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

Protein degradation: CUL-3 and BTB--partners in proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Insights into programmed cell death through structural biology

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The CD95(APO-1/Fas) DISC and beyond

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Shared principles in NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Death receptor signal transducers: nodes of coordination in immune signaling networks

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin-mediated regulation of TNFR1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin signalling in the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

https://api.crossref.org/works/10.1038%2FCDD.2009.168

1 reference

7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Back to the future with ubiquitin

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

A genomic and functional inventory of deubiquitinating enzymes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

A proteomics approach to understanding protein ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

RING domain E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Linear polyubiquitination: a new regulator of NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Distinct functional surface regions on ubiquitin

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

IAPs: what's in a name?

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The TNF receptor 1: a split personality complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

TNF-alpha induces two distinct caspase-8 activation pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Physiological roles and mechanisms of signaling by TRAF2 and TRAF5.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

An intact zinc ring finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-kappaB activation but is dispensable for c-Jun N-terminal kinase signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Isolation and characterization of two novel A20-like proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

cFLIP regulation of lymphocyte activation and development

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

IAP proteins: blocking the road to death's door

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

XIAP discriminates between type I and type II FAS-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Inactivation of effector caspases through nondegradative polyubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

IAPs, RINGs and ubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

The alpha-5 helix of Bax is sensitive to ubiquitin-dependent degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.168

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.168

1 reference

21 August 2017

1 reference

PubMed ID

19893571