(Q37630588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19903072%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Molecular and cellular biology of rhabdomyosarcoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19903072%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

1 reference

2

1 reference

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12 February 2020

Pier-Luigi Lollini

series ordinal

4

1 reference

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12 February 2020

Patrizia Nanni

series ordinal

5

1 reference

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12 February 2020

3

Giordano Nicoletti

1 reference

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12 February 2020

1

Carla De Giovanni

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19903072%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

1 November 2009

1 reference

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12 February 2020

1 reference

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12 February 2020

volume

5

1 reference

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12 February 2020

page(s)

1449-1475

1 reference

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12 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19903072%20AND%20SRC:MED&resulttype=core&format=json

Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2005

12 February 2020

cites work

1 reference

Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification--an Intergroup Rhabdomyosarcoma Study

21 January 2018

1 reference

Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?

21 January 2018

1 reference

Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group

21 January 2018

1 reference

Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the Children's Oncology Group

21 January 2018

1 reference

Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups.

21 January 2018

1 reference

Rhabdomyosarcoma--working out the pathways

21 January 2018

1 reference

The formation of skeletal muscle: from somite to limb

21 January 2018

1 reference

MyoD and the transcriptional control of myogenesis

21 January 2018

1 reference

Skeletal muscle stem cells

21 January 2018

1 reference

An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: the Children's Oncology Group experience

21 January 2018

1 reference

Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: a tissue microarray study of 71 primary tumors including correlation with molecular phenotype.

21 January 2018

1 reference

Comparing adult and pediatric rhabdomyosarcoma in the surveillance, epidemiology and end results program, 1973 to 2005: an analysis of 2,600 patients

21 January 2018

1 reference

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

21 January 2018

1 reference

Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IV.

21 January 2018

1 reference

Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances

21 January 2018

1 reference

Clinical relevance of molecular genetics to paediatric sarcomas

21 January 2018

1 reference

Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma

21 January 2018

1 reference

Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.

21 January 2018

1 reference

A novel PAX3 rearrangement in embryonal rhabdomyosarcoma.

21 January 2018

1 reference

Mechanisms of sarcoma development

21 January 2018

1 reference

A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting

21 January 2018

1 reference

A common region of loss of heterozygosity in Wilms' tumor and embryonal rhabdomyosarcoma distal to the D11S988 locus on chromosome 11p15.5.

21 January 2018

1 reference

Allelotype of pediatric rhabdomyosarcoma

21 January 2018

1 reference

Growth regulation, imprinted genes, and chromosome 11p15.5.

21 January 2018

1 reference

Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

21 January 2018

1 reference

Expression and parental imprinting of the H19 gene in human rhabdomyosarcoma.

21 January 2018

1 reference

Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma

21 January 2018

1 reference

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

21 January 2018

1 reference

A molecular map of mesenchymal tumors

21 January 2018

1 reference

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

21 January 2018

1 reference

Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas

21 January 2018

1 reference

Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas

21 January 2018

1 reference

Defining the gene expression signature of rhabdomyosarcoma by meta-analysis.

21 January 2018

1 reference

Profiling and functional annotation of mRNA gene expression in pediatric rhabdomyosarcoma and Ewing's sarcoma

21 January 2018

1 reference

Novel method for the production of multiple colour chromosome paints for use in karyotyping by fluorescence in situ hybridisation

21 January 2018

1 reference

Characterization of the A673 cell line (Ewing tumor) by molecular cytogenetic techniques

21 January 2018

1 reference

In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma

21 January 2018

1 reference

Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma

21 January 2018

1 reference

Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

21 January 2018

1 reference

The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture

21 January 2018

1 reference

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

21 January 2018

1 reference

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

1 reference

PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression

21 January 2018

1 reference

Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma.

21 January 2018

1 reference

The oncogenic transcription factor PAX3-FKHR can convert fibroblasts into contractile myotubes.

21 January 2018

1 reference

Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma

21 January 2018

1 reference

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

21 January 2018

1 reference

An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene

21 January 2018

1 reference

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

21 January 2018

1 reference

Effects of PAX3-FKHR on malignant phenotypes in alveolar rhabdomyosarcoma

21 January 2018

1 reference

PAX3-FOXO1 fusion gene in rhabdomyosarcoma

21 January 2018

1 reference

Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR

21 January 2018

1 reference

Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor

21 January 2018

1 reference

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target

21 January 2018

1 reference

A PANorama of PAX genes in cancer and development

21 January 2018

1 reference

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

21 January 2018

1 reference

PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN.

21 January 2018

1 reference

A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation

21 January 2018

1 reference

PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.

21 January 2018

1 reference

Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma

21 January 2018

1 reference

Vascular endothelial growth factor acts in an autocrine manner in rhabdomyosarcoma cell lines and can be inhibited with all-trans-retinoic acid

21 January 2018

1 reference

Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein

21 January 2018

1 reference

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression

21 January 2018

1 reference

Mutation and expression analyses of the MET and CDKN2A genes in rhabdomyosarcoma with emphasis on MET overexpression

21 January 2018

1 reference

Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors

21 January 2018

1 reference

Expression of insulin-like growth factor 2 in mesenchymal neoplasms

21 January 2018

1 reference

The insulin-like growth factor system and sarcomas.

21 January 2018

1 reference

The IGF‐1 receptor in cancer biology

21 January 2018

1 reference

Insulin and insulin-like growth factor signalling in neoplasia

21 January 2018

1 reference

The role of IGF-1R in pediatric malignancies

21 January 2018

1 reference

Customizing the targeting of IGF-1 receptor

21 January 2018

1 reference

Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group

21 January 2018

1 reference

A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop

21 January 2018

1 reference

Targeting insulin-like growth factor 1 receptor in sarcomas

21 January 2018

1 reference

Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma

21 January 2018

1 reference

Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody

21 January 2018

1 reference

PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

21 January 2018

1 reference

Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

21 January 2018

1 reference

The imprinted H19 noncoding RNA is a primary microRNA precursor

21 January 2018

1 reference

p53 family members in myogenic differentiation and rhabdomyosarcoma development

21 January 2018

1 reference

P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines

21 January 2018

1 reference

Molecular pathogenesis of rhabdomyosarcoma

21 January 2018

1 reference

Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma.

21 January 2018

1 reference

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype.

21 January 2018

1 reference

Risk of second malignancies in survivors of retinoblastoma: more than 40 years of follow-up

21 January 2018

1 reference

Role for amplification and expression of glypican-5 in rhabdomyosarcoma

21 January 2018

1 reference

Genomic and clinical analyses of 2p24 and 12q13-q14 amplification in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group

21 January 2018

1 reference

Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies

21 January 2018

1 reference

Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

21 January 2018

1 reference

Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome.

21 January 2018

1 reference

An anti-apoptotic role for NGF receptors in human rhabdomyosarcoma

21 January 2018

1 reference

Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells

21 January 2018

1 reference

FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes

21 January 2018

1 reference

Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors

21 January 2018

1 reference

Expression of receptor tyrosine kinases and apoptotic molecules in rhabdomyosarcoma: correlation with overall survival in 105 patients.

21 January 2018

1 reference

The MET receptor tyrosine kinase contributes to invasive tumour growth in rhabdomyosarcomas

21 January 2018

1 reference

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis.

21 January 2018

1 reference

PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

21 January 2018

1 reference

Opposing control of rhabdomyosarcoma growth and differentiation by myogenin and interleukin 4.

21 January 2018

1 reference

Different telomere maintenance mechanisms in alveolar and embryonal rhabdomyosarcoma

21 January 2018

1 reference

Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo

21 January 2018

1 reference

The genetics of vertebrate myogenesis

21 January 2018

1 reference

Skeletal muscle as a paradigm for regenerative biology and medicine

21 January 2018

1 reference

The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7.

21 January 2018

1 reference

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts

21 January 2018

1 reference

Forkhead box protein O1 negatively regulates skeletal myocyte differentiation through degradation of mammalian target of rapamycin pathway components

21 January 2018

1 reference

MicroRNAs flex their muscles

21 January 2018

1 reference

MicroRNA control of muscle development and disease

21 January 2018

1 reference

NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma

21 January 2018

1 reference

IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop

21 January 2018

1 reference

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis

21 January 2018

1 reference

Pax3 functions at a nodal point in melanocyte stem cell differentiation

21 January 2018

1 reference

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination

21 January 2018

1 reference

MicroRNA expression signature of human sarcomas.

21 January 2018

1 reference

Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma

21 January 2018

1 reference

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

21 January 2018

1 reference

In vitro differentiation of rhabdomyosarcomas induced by nickel or by Moloney murine sarcoma virus

21 January 2018

1 reference

Biomaterial-induced sarcoma: A novel model to study preneoplastic change

21 January 2018

1 reference

Biological tolerance of different materials in bulk and nanoparticulate form in a rat model: sarcoma development by nanoparticles

21 January 2018

1 reference

Nevoid basal cell carcinoma (Gorlin) syndrome

21 January 2018

1 reference

Rhabdomyosarcoma in patients with constitutional mismatch-repair-deficiency syndrome

21 January 2018

1 reference

Prenatal X-ray exposure and rhabdomyosarcoma in children: a report from the children's oncology group.

21 January 2018

1 reference

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

21 January 2018

1 reference

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

21 January 2018

1 reference

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

21 January 2018

1 reference

Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene

21 January 2018

1 reference

A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR.

21 January 2018

1 reference

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

21 January 2018

1 reference

Transgenic model of cardiac rhabdomyosarcoma formation

21 January 2018

1 reference

Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts

21 January 2018

1 reference

Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.

21 January 2018

1 reference

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

21 January 2018

1 reference

Redundancy of autocrine loops in human rhabdomyosarcoma cells: induction of differentiation by suramin

21 January 2018

1 reference

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

21 January 2018

1 reference

Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

21 January 2018

1 reference

The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors

21 January 2018

1 reference

The TOR pathway: a target for cancer therapy

21 January 2018

1 reference

The biology behind mTOR inhibition in sarcoma

21 January 2018

1 reference

Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program.

21 January 2018

1 reference

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.

21 January 2018

1 reference

Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program

21 January 2018

1 reference

Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program

21 January 2018

1 reference

Muscle regulatory factor MRF4 activates differentiation in rhabdomyosarcoma RD cells through a positive-acting C-terminal protein domain

21 January 2018

1 reference

A retrovirus-based system to stably silence GDF-8 expression and enhance myogenic differentiation in human rhabdomyosarcoma cells

21 January 2018

1 reference

MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.

21 January 2018

1 reference

Identification of new genes related to the myogenic differentiation arrest of human rhabdomyosarcoma cells

21 January 2018

1 reference

Rhabdomyosarcomas are potential target of MAGE-specific immunotherapies.

21 January 2018

1 reference

Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors

21 January 2018

1 reference

A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.

21 January 2018

1 reference

Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice

21 January 2018

1 reference

RMZ: a new cell line from a human alveolar rhabdomyosarcoma. In vitro expression of embryonic myosin

21 January 2018

1 reference

Molecular characterization of the pediatric preclinical testing panel

21 January 2018

1 reference

PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma

21 January 2018

1 reference

The PAX3-FKHR fusion gene of rhabdomyosarcoma cooperates with loss of p16INK4A to promote bypass of cellular senescence

21 January 2018

1 reference

Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma

21 January 2018

1 reference

Gene expression profiling identifies potential relevant genes in alveolar rhabdomyosarcoma pathogenesis and discriminatesPAX3-FKHR positive and negative tumors

21 January 2018

1 reference

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome

21 January 2018

1 reference

Rhabdomyosarcoma development in mice lacking Trp53 and Fos

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FON.09.97

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19903072%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference