(Q37718251)

22 August 2017

1 reference

title

Targeting the Notch signaling pathway in autoimmune diseases (English)

1 reference

22 August 2017

Daoxin Ma

1

1 reference

22 August 2017

Yuanchao Zhu

series ordinal

2

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22 August 2017

Chunyan Ji

series ordinal

3

1 reference

22 August 2017

Ming Hou

series ordinal

4

1 reference

22 August 2017

language of work or name

English

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publication date

1 May 2010

1 reference

Expert Opinion on Therapeutic Targets

22 August 2017

published in

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22 August 2017

volume

14

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22 August 2017

issue

5

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22 August 2017

page(s)

553-565

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Gene therapy in autoimmune diseases: challenges and opportunities

22 August 2017

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21 January 2018

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Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

21 January 2018

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The Notch1 receptor is cleaved constitutively by a furin-like convertase

21 January 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

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Notch receptors and hematopoiesis

21 January 2018

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Multiple functions of Notch signaling in self-renewing organs and cancer.

21 January 2018

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Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells

21 January 2018

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RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

21 January 2018

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An early haematopoietic defect in mice lacking the transcription factor GATA-2

21 January 2018

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Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1-Fc chimeric protein

21 January 2018

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Hematopoietic stem cell fate is established by the Notch-Runx pathway

21 January 2018

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HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

21 January 2018

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Osteoblastic cells regulate the haematopoietic stem cell niche

21 January 2018

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Notch regulation of lymphocyte development and function.

21 January 2018

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Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

21 January 2018

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Notch signaling specifies megakaryocyte development from hematopoietic stem cells.

21 January 2018

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T-cell development, doing it in a dish.

21 January 2018

1 reference

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Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch1 signaling and regulatory T cell function

21 January 2018

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Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta

21 January 2018

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Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

21 January 2018

1 reference

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Notch and BCR signaling synergistically promote the proliferation of Raji B-lymphoma cells

21 January 2018

1 reference

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Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells

21 January 2018

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21 January 2018

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Notch1 augments NF-kappaB activity by facilitating its nuclear retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

The interplay between DSL proteins and ubiquitin ligases in Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Regulation of notch signaling by o-linked fucose.

21 January 2018

1 reference

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The ADAM metalloproteinases

21 January 2018

1 reference

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Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways.

21 January 2018

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Emerging role of Notch in stem cells and cancer

21 January 2018

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Recent insights into the role of Notch signaling in tumorigenesis

21 January 2018

1 reference

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Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression

21 January 2018

1 reference

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Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch signaling contributes to the pathogenesis of human osteosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

21 January 2018

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Induction of CCL2 by siMAML1 through upregulation of TweakR in melanoma cells

21 January 2018

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DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch signaling in leukemias and lymphomas

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728221003752750

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

21 January 2018

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Galectins in the tumor endothelium: opportunities for combined cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch signaling inhibits the growth of the human chronic myeloid leukemia cell line K562.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch1 control of oligodendrocyte differentiation in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

The nervous system and innate immunity: the neuropeptide connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Targeting Notch signaling in autoimmune and lymphoproliferative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Tolerogenic strategies to halt or prevent type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch signaling: a mediator of beta-cell de-differentiation in diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Microbial influences in inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Requirement of Notch activation during regeneration of the intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Prevalence of immune thrombocytopenia: analyses of administrative data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

The cellular immunology associated with autoimmune thrombocytopenic purpura: an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Profile of Th17 cytokines (IL-17, TGF-beta, IL-6) and Th1 cytokine (IFN-gamma) in patients with immune thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Management of adult idiopathic thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Notch emerges as new cancer drug target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Possible mechanisms of action of NSAIDs and related compounds that modulate gamma-secretase cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Cross-talk between Notch and EGFR signaling in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Activating Notch1 mutations in mouse models of T-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003752750

10.1517/14728221003752750

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference