(Q37745603)

22 August 2017

1 reference

title

Activation of fibroblasts in cancer stroma (English)

1 reference

22 August 2017

2

Antti Vaheri

1 reference

22 August 2017

Kati Räsänen

1

1 reference

PubMed ID

20451516

22 August 2017

language of work or name

English

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publication date

6 May 2010

1 reference

Experimental Cell Research

22 August 2017

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22 August 2017

316

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22 August 2017

2713-2722

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22 August 2017

17

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Evolution of cooperation among tumor cells

22 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

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The Hallmarks of Cancer

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Co-evolution of tumor cells and their microenvironment

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VEGFs and receptors involved in angiogenesis versus lymphangiogenesis

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The tumor microenvironment and its contribution to tumor evolution toward metastasis

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Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

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Mechanisms of force generation and transmission by myofibroblasts

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Myofibroblasts and mechano-regulation of connective tissue remodelling

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

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The myofibroblast and its tumours

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Cell-cell communication in carcinogenesis

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Involvement of gap junctions in tumor suppression: analysis of genetically-manipulated mice

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

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Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

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From mechanotransduction to extracellular matrix gene expression in fibroblasts.

7 January 2021

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Mechanics, malignancy, and metastasis: the force journey of a tumor cell

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Mechanotransduction through growth-factor shedding into the extracellular space

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The myofibroblast: one function, multiple origins

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Fibroblasts and myofibroblasts: their source, function and role in disease.

7 January 2021

1 reference

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Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

7 January 2021

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The basics of epithelial-mesenchymal transition

7 January 2021

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The role of endothelial-to-mesenchymal transition in cancer progression

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The senescence-associated secretory phenotype: the dark side of tumor suppression

7 January 2021

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Origin of carcinoma associated fibroblasts

7 January 2021

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Fibroblast independency in tumors: implications in cancer therapy

7 January 2021

1 reference

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Identification of fibroblast heterogeneity in the tumor microenvironment

7 January 2021

1 reference

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Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma

7 January 2021

1 reference

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

7 January 2021

1 reference

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7 January 2021

Fibroblasts in cancer

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PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

7 January 2021

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Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23

7 January 2021

1 reference

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Seprase: an overview of an important matrix serine protease

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1 reference

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Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?

7 January 2021

1 reference

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No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

7 January 2021

1 reference

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Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution

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1 reference

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Seed in soil, with an epigenetic view

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1 reference

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Tumor microenvironment and angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Stromal myofibroblasts are drivers of invasive cancer growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

7 January 2021

1 reference

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Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma.

7 January 2021

1 reference

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The multifaceted role of periostin in tumorigenesis

7 January 2021

1 reference

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Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

7 January 2021

1 reference

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A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

7 January 2021

1 reference

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Caveolin-1 in tumor progression: the good, the bad and the ugly.

7 January 2021

1 reference

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An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

7 January 2021

1 reference

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An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation

7 January 2021

1 reference

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Stromal cell expression of caveolin-1 predicts outcome in breast cancer

7 January 2021

1 reference

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Podoplanin expression identified in stromal fibroblasts as a favorable prognostic marker in patients with colorectal carcinoma.

7 January 2021

1 reference

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Friends or foes - bipolar effects of the tumour stroma in cancer

7 January 2021

1 reference

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Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

The extracellular matrix: not just pretty fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion

7 January 2021

1 reference

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MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma

7 January 2021

1 reference

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Stromal Expression of MMP-13 Is Required for Melanoma Invasion and Metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

TFPI-2 silencing increases tumour progression and promotes metalloproteinase 1 and 3 induction through tumour-stromal cell interactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model

7 January 2021

1 reference

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Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

7 January 2021

1 reference

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The urokinase receptor: focused cell surface proteolysis, cell adhesion and signaling

7 January 2021

1 reference

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Plasminogen activation and cancer

7 January 2021

1 reference

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Ovarian cancer cells stimulate uPA gene expression in fibroblastic stromal cells via multiple paracrine and autocrine mechanisms

7 January 2021

1 reference

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Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures

7 January 2021

1 reference

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The MET receptor tyrosine kinase in invasion and metastasis

7 January 2021

1 reference

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Targeting the c-Met signaling pathway in cancer

7 January 2021

1 reference

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Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors

7 January 2021

1 reference

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Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.032

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

7 January 2021

1 reference

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Functions and mechanisms of action of CCN matricellular proteins

7 January 2021

1 reference

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7 January 2021

1 reference

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Cytokine-based transformation of immune surveillance into tumor-promoting inflammation

7 January 2021

1 reference

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Protumor vs antitumor functions of IL-17.

7 January 2021

1 reference

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Chemokines in tumor-associated angiogenesis.

7 January 2021

1 reference

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CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

7 January 2021

1 reference

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CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer

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1 reference

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Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.

7 January 2021

1 reference

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The biology of chemokines and their receptors

7 January 2021

1 reference

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Responsiveness of stromal fibroblasts to IFN-gamma blocks tumor growth via angiostasis

7 January 2021

1 reference

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Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

7 January 2021

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p53--a Jack of all trades but master of none

7 January 2021

1 reference

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Breast-Cancer Stromal Cells withTP53Mutations and Nodal Metastases

7 January 2021

1 reference

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p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy

7 January 2021

1 reference

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

7 January 2021

1 reference

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The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

7 January 2021

1 reference

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Cyclooxygenase-2 regulates survival, migration, and invasion of human endometriotic cells through multiple mechanisms.

7 January 2021

1 reference

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TGF-beta1 causes epithelial-mesenchymal transition in HaCaT derivatives, but induces expression of COX-2 and migration only in benign, not in malignant keratinocytes

7 January 2021

1 reference

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Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis

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1 reference

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Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression

7 January 2021

1 reference

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On the Origin of Cancer Cells

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1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

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1 reference

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The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

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Pazopanib: an oral multitargeted tyrosine kinase inhibitor for use in renal cell carcinoma

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Integrins in cancer: biological implications and therapeutic opportunities

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Progress in the development of matrix metalloproteinase inhibitors

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Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer

7 January 2021

1 reference

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The urokinase plasminogen activator system: a target for anti-cancer therapy.

7 January 2021

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A phase Ib study of AMG 102 in combination with bevacizumab or motesanib in patients with advanced solid tumors

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Cancer chemoprevention by cyclooxygenase 2 (COX-2) blockade: results of case control studies.

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Fibroblasts in three dimensional matrices: cell migration and matrix remodeling

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Nemosis, a novel way of fibroblast activation, in inflammation and cancer

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Formation and activation of fibroblast spheroids depend on fibronectin-integrin interaction

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1 reference

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Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness

7 January 2021

1 reference

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Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis

7 January 2021

1 reference

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Fibroblast nemosis arrests growth and induces differentiation of human leukemia cells

7 January 2021

1 reference

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Clustering of fibroblasts induces proinflammatory chemokine secretion promoting leukocyte migration.

7 January 2021

1 reference

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Fibroblast nemosis induces angiogenic responses of endothelial cells

7 January 2021

1 reference

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Nemosis of fibroblasts is inhibited by benign HaCaT keratinocytes but promoted by malignant HaCaT cells

7 January 2021

1 reference

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10.1016/J.YEXCR.2010.04.032

7 January 2021

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20451516