(Q37764530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Roger Reddel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Jeremy D Henson

series ordinal

1

1 reference

22 August 2017

Roger R Reddel

series ordinal

2

1 reference

22 August 2017

language of work or name

English

0 references

publication date

11 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

FEBS Letters

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

584

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

3800-3811

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20542034%20AND%20SRC:MED&resulttype=core&format=json

Telomere maintenance mechanisms and cellular immortalization.

5 February 2020

cites work

1 reference

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The role of senescence and immortalization in carcinogenesis

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A survey of telomerase activity in human cancer

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An alternative pathway for yeast telomere maintenance rescues est1- senescence

21 January 2018

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Telomere maintenance by telomerase and by recombination can coexist in human cells

21 January 2018

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Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells

21 January 2018

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Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway

21 January 2018

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Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells

21 January 2018

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Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

21 January 2018

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How shelterin protects mammalian telomeres

21 January 2018

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Alternative lengthening of telomeres: models, mechanisms and implications

21 January 2018

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Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.

21 January 2018

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The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

21 January 2018

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Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

21 January 2018

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Telomere maintenance requires the RAD51D recombination/repair protein

21 January 2018

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Telomere recombination requires the MUS81 endonuclease.

21 January 2018

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Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts

21 January 2018

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Alternative lengthening of telomeres in mammalian cells

21 January 2018

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Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Control of telomere length by a trimming mechanism that involves generation of t-circles

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Three-dimensional organization of promyelocytic leukemia nuclear bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

PML protein isoforms and the RBCC/TRIM motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Double functions for the Mre11 complex during DNA double-strand break repair and replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

DNA damage induces alternative lengthening of telomeres (ALT) associated promyelocytic leukemia bodies that preferentially associate with linear telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomerase-independent telomere length maintenance in the absence of alternative lengthening of telomeres-associated promyelocytic leukemia bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

A novel telomere structure in a human alternative lengthening of telomeres cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Homologous recombination generates T-loop-sized deletions at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomeric repeats on small polydisperse circular DNA (spcDNA) and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Ku86 represses lethal telomere deletion events in human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

TRF2 promotes, remodels and protects telomeric Holliday junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Molecular and structural transactions at human DNA replication origins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Activation of the ALT pathway for telomere maintenance can affect other sequences in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Homologous recombination in human telomerase‐positive and ALT cells occurs with the same frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Immortal, telomerase-negative cell lines derived from a Li-Fraumeni syndrome patient exhibit telomere length variability and chromosomal and minisatellite instabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Minisatellites: mutability and genome architecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Extrachromosomal circular DNA in eukaryotes: possible involvement in the plasticity of tandem repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Alternative lengthening of telomeres is characterized by high rates of telomeric exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere lengthening early in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

A role for monoubiquitinated FANCD2 at telomeres in ALT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Strand-Specific Postreplicative Processing of Mammalian Telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Epigenetic regulation of telomeres in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Frequent occurrence of UVB-induced sister chromatid exchanges in telomere regions and its implication to telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Purification of proteins associated with specific genomic Loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Short telomeres initiate telomere recombination in primary and tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

How telomeres solve the end-protection problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Unusual telomeric DNAs in human telomerase-negative immortalized cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

FEN1 contributes to telomere stability in ALT-positive tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma of the colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Zscan4 regulates telomere elongation and genomic stability in ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

p53 in recombination and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Mutant metabolic enzymes are at the origin of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

IDH1 and IDH2: not your typical oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Unwinding the functions of the Pif1 family helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Alternative lengthening of telomeres frequently occurs in mismatch repair system-deficient gastric carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Multiple mechanisms of telomere maintenance exist in liposarcomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere-maintenance mechanisms in soft-tissue malignant fibrous histiocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomerase activation in human fibroblasts during escape from crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

In situ analysis of changes in telomere size during replicative aging and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Immortalization of normal human embryonic fibroblasts by introduction of either the human papillomavirus type 16 E6 or E7 gene alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Mutation in p53 and de-regulation of p53-related gene expression in three human cell lines immortalized with 4-nitroquinoline 1-oxide or 60Co gamma rays

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Telomere elongation observed in immortalized human fibroblasts by treatment with 60Co gamma rays or 4-nitroquinoline 1-oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Normal telomere maintenance in immortal ataxia telangiectasia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Aflatoxin B1-induced immortalization of cultured skin fibroblasts from a patient with Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Extended lifespan and immortalization of human fibroblasts induced by X-ray irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Genetic mechanisms of tumor suppression by the human p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

Inactivation of p53 gene in human and murine osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009

p53 protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.06.009