(Q37767356)

22 August 2017

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title

Targeting the tumour vasculature: insights from physiological angiogenesis (English)

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22 August 2017

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3

Napoleone Ferrara

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22 August 2017

Alicia S Chung

1

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PubMed ID

20574450

22 August 2017

John Lee

series ordinal

2

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PubMed ID

20574450

22 August 2017

language of work or name

English

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publication date

1 July 2010

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22 August 2017

Nature Reviews Cancer

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22 August 2017

10

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22 August 2017

505-514

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22 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nrc2868

22 August 2017

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Autocrine VEGF signaling is required for vascular homeostasis

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Chronic DLL4 blockade induces vascular neoplasms

31 March 2020

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Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

31 March 2020

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Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models

31 March 2020

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31 March 2020

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PlGF blockade does not inhibit angiogenesis during primary tumor growth

31 March 2020

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Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

31 March 2020

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31 March 2020

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Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma

31 March 2020

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Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts

31 March 2020

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PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment

31 March 2020

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Trophic macrophages in development and disease

31 March 2020

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

31 March 2020

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Stromal gene expression predicts clinical outcome in breast cancer

31 March 2020

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Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

31 March 2020

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Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

31 March 2020

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

31 March 2020

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The role of myeloid cells in the promotion of tumour angiogenesis

31 March 2020

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

31 March 2020

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An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

31 March 2020

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The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent.

31 March 2020

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Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells

31 March 2020

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31 March 2020

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Endogenous inhibitors of angiogenesis.

31 March 2020

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31 March 2020

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

31 March 2020

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Tumor angiogenesis: cause or consequence of cancer?

31 March 2020

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Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

31 March 2020

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Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

31 March 2020

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Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

31 March 2020

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31 March 2020

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Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function

31 March 2020

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Pathways mediating VEGF-independent tumor angiogenesis

31 March 2020

1 reference

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

31 March 2020

1 reference

The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells

31 March 2020

1 reference

Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization

31 March 2020

1 reference

Neutrophils infiltrating the endometrium express vascular endothelial growth factor: potential role in endometrial angiogenesis

31 March 2020

1 reference

Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse model.

31 March 2020

1 reference

Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response

31 March 2020

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Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

31 March 2020

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Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE)

31 March 2020

1 reference

The molecular basis of vascular lumen formation in the developing mouse aorta

31 March 2020

1 reference

Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption

31 March 2020

1 reference

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

31 March 2020

1 reference

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

31 March 2020

1 reference

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.

31 March 2020

1 reference

12 December 2020

Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy?

1 reference

12 December 2020

Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression

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12 December 2020

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

1 reference

12 December 2020

Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders

1 reference

12 December 2020

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis

1 reference

12 December 2020

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

1 reference

12 December 2020

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

1 reference

12 December 2020

Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2868

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22 August 2017

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PubMed ID

20574450