(Q37824123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Hijacking solute carriers for proton-coupled drug transport (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author

Catriona M H Anderson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

David T Thwaites

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

1 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

364-377

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Inhibition of intestinal dipeptide transport by the neuropeptide VIP is an anti-absorptive effect via the VPAC1 receptor in a human enterocyte-like cell line (Caco-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Indirect regulation of the intestinal H+-coupled amino acid transporter hPAT1 (SLC36A1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Regulation of intestinal hPepT1 (SLC15A1) activity by phosphodiesterase inhibitors is via inhibition of NHE3 (SLC9A3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Transport of drugs by proton-coupled peptide transporters: pearls and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Excitatory amino acid transporters as potential drug targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Regulation and Modulation of pH in the Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Demonstration and modification of intervillous pH profiles in rat small intestine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

pH regulation and proton signalling by glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Molecular features, regulation, and function of monocarboxylate transporters: implications for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Expression cloning of a mammalian proton-coupled oligopeptide transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Is intestinal peptide transport energized by a proton gradient?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Expression and membrane localization of MCT isoforms along the length of the human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Regulation of human peptide transporter 1 (PEPT1) in gastric cancer cells by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Role and relevance of PEPT2 in drug disposition, dynamics, and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The Na(+)/H(+) exchanger: a target for cardiac therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na+/H+ exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Dual modes of 5-(N-ethyl-N-isopropyl)amiloride modulation of apical dipeptide uptake in the human small intestinal epithelial cell line Caco-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

H+-peptide cotransport in the human bile duct epithelium cell line SK-ChA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Glycylsarcosine uptake in rabbit renal brush border membrane vesicles isolated from outer cortex or outer medulla: evidence for heterogeneous distribution of oligopeptide transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Acid microclimate in coeliac and Crohn's disease: a model for folate malabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The effect of E. coli STa enterotoxin on the absorption of weakly dissociable drugs from rat proximal jejunum in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Human reduced folate carrier: translation of basic biology to cancer etiology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Serotonin, L-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Cancer detection using a PET tracer, 11C-glycylsarcosine, targeted to H+/peptide transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Isolation and function of the amino acid transporter PAT1 (slc36a1) from rabbit and discrimination between transport via PAT1 and system IMINO in renal brush-border membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Monocarboxylate transporter MCT1 is a target for immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Mechanism and regulation of human intestinal niacin uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Role of PEPT2 in the choroid plexus uptake of glycylsarcosine and 5-aminolevulinic acid: studies in wild-type and null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The mitochondrial transporter family (SLC25): physiological and pathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Mammalian peptide transporters as targets for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Targeted disruption of the peptide transporter Pept2 gene in mice defines its physiological role in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Identification and characterization of a lysosomal transporter for small neutral amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Identification of an intestinal heme transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Changes in the surface pH of voltage-clamped snail neurones apparently caused by H+ fluxes through a channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Deciphering the mechanisms of intestinal imino (and amino) acid transport: the redemption of SLC36A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

D-cycloserine transport in human intestinal epithelial (Caco-2) cells: mediation by a H(+)-coupled amino acid transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Gamma-Aminobutyric acid (GABA) transport across human intestinal epithelial (Caco-2) cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

H/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na/H exchanger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

L-alanine absorption in human intestinal Caco-2 cells driven by the proton electrochemical gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Blood-brain barrier transporters and response to CNS-active drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Functional linkage of H+/peptide transporter PEPT2 and Na+/H+ exchanger in primary cultures of astrocytes from mouse cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The relevance of tumour pH to the treatment of malignant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Molecular and cellular physiology of renal organic cation and anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

The proton-coupled folate transporter: impact on pemetrexed transport and on antifolates activities compared with the reduced folate carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00027.2010

10.1152/PHYSIOL.00027.2010

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186281%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference