(Q37878781)

24 August 2017

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title

Activating the damaged basal forebrain cholinergic system: tonic stimulation versus signal amplification (English)

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24 August 2017

M Sarter

1

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PubMed ID

2160662

24 August 2017

J P Bruno

series ordinal

2

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PubMed ID

2160662

24 August 2017

P Dudchenko

series ordinal

3

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24 August 2017

1 January 1990

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24 August 2017

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24 August 2017

101

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24 August 2017

1-17

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24 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/bf02253710

24 August 2017

0 references

cites work

Physostigmine reversal of diazepam-induced hypnosis. A study in human volunteers

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https://api.crossref.org/works/10.1007%2FBF02253710

Memory performance in individuals with primary degenerative dementia: its similarity to diazepam-induced impairments.

21 January 2018

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Muscarinic agonist therapy of Alzheimer's disease. A clinical trial of RS-86.

21 January 2018

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Memory decline in the aged: treatment with lecithin and physostigmine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Failure of cholinergic agonist RS-86 to improve cognition and movement in PSP despite effects on sleep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

The effects of intravenous diazepam and hyoscine upon human memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Mechanisms of action of acetylcholine in the guinea-pig cerebral cortex in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Oral physostigmine treatment of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Effects of diazepam on adenosine and acetylcholine release from rat cerebral cortex: further evidence for a purinergic mechanism in action of diazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Disinhibitory properties of beta-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Diazepam-induced amnesia: a neuropharmacological model of an "organic amnestic syndrome".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02253710

Changes in cortical acetylcholine output induced by modulation of the nucleus basalis.

21 January 2018

1 reference

12 December 2020

Effects of oral physostigmine in Alzheimer's disease.

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12 December 2020

Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes

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12 December 2020

gamma-Aminobutyric acid (GABA) receptor stimulation. IV. Effect of progabide (SL 76002) and other GABAergic agents on acetylcholine turnover in rat brain areas

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12 December 2020

The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide). A potent, specific muscarinic acetylcholine receptor agonist

1 reference

12 December 2020

Improved radial maze performance induced by the benzodiazepine antagonist ZK 93 426 in lesioned and alcohol-treated rats.

1 reference

12 December 2020

Enhancement of learning and memory in mice by a benzodiazepine antagonist

1 reference

12 December 2020

Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain.

1 reference

12 December 2020

The cholinergic hypothesis--ten years on.

1 reference

12 December 2020

The distribution and origin of glutamate decar☐ylase and choline acetyltransferase in ventral pallidum and other basal forebrain regions

1 reference

12 December 2020

Pharmacological evaluation of GABAergic and glutamatergic inputs to the nucleus basalis--cortical and the septal-hippocampal cholinergic projections

1 reference

12 December 2020

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

1 reference

12 December 2020

Co-existence of galanin and acetylcholine: is galanin involved in memory processes and dementia?

1 reference

12 December 2020

New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata

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12 December 2020

Only certain antiepileptic drugs prevent seizures induced by pilocarpine

1 reference

12 December 2020

Regional decreases of cortical choline acetyltransferase after lesions of the septal area and in the area of nucleus basalis magnocellularis.

1 reference

12 December 2020

Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.

1 reference

12 December 2020

Presynaptic serotonergic dysfunction in patients with Alzheimer's disease.

1 reference

12 December 2020

A comparison of the localization of choline acetyltransferase and glutamate decarboxylase immunoreactivity in rat cerebral cortex.

1 reference

12 December 2020

Effects of bilateral ibotenate-induced lesions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex

1 reference

12 December 2020

Benzodiazepine receptor sites in the human brain: autoradiographic mapping.

1 reference

12 December 2020

Basal forebrain neurons projecting to the rat frontoparietal cortex: electrophysiological and pharmacological properties

1 reference

12 December 2020

Physostigmine and arecoline: effects of intravenous infusions in Alzheimer presenile dementia

1 reference

12 December 2020

Neuronal loss and GABAergic innervation in the basal forebrain

1 reference

12 December 2020

Bidirectional effects of beta-carbolines and benzodiazepines on cognitive processes.

1 reference

12 December 2020

Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788.

1 reference

12 December 2020

Effect of cholinesterase inhibitors on Morris water task behavior following lesions of the nucleus basalis magnocellularis.

1 reference

12 December 2020

Kindling and withdrawal changes at the benzodiazepine receptor

1 reference

12 December 2020

Hemicholinium-3 impairs spatial learning and the deficit is reversed by cholinomimetics.

1 reference

12 December 2020

A note on the connections and development of the nucleus accumbens

1 reference

12 December 2020

Do tetrahydroaminoacridine (THA) and physostigmine restore acetylcholine release in Alzheimer brains via nicotinic receptors?

1 reference

12 December 2020

Patterns of memory failure after scopolamine treatment: implications for cholinergic hypotheses of dementia

1 reference

12 December 2020

Pharmacological alleviation of cholinergic lesion induced memory deficits in rats

1 reference

12 December 2020

Ventral pallidal neuronal responses to dopamine receptor stimulation in the nucleus accumbens

1 reference

12 December 2020

Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer's disease

1 reference

12 December 2020

Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.

1 reference

12 December 2020

Physostigmine, a highly potent antidote for acute experimental diazepam intoxication.

1 reference

12 December 2020

Effects of GABAergic drugs in vivo on high-affinity choline uptake in vitro in mouse hippocampal synaptosomes.

1 reference

12 December 2020

Long-term enhancement of evoked potentials in cat somatosensory cortex produced by co-activation of the basal forebrain and cutaneous receptors

1 reference

12 December 2020

Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: a review and some new results.

1 reference

12 December 2020

Autoradiographic analyses of agonist binding to muscarinic receptor subtypes

1 reference

12 December 2020

Lack of GABAergic modulation of acetylcholine turnover in the rat thalamus.

1 reference

12 December 2020

Beta-carboline interactions at the BZ-GABA receptor chloride-ionophore complex in the rat cerebral cortex

1 reference

12 December 2020

Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain.

1 reference

12 December 2020

Dendritic proliferation in the aging brain as a compensatory repair mechanism

1 reference

12 December 2020

Change in nicotinic receptor subtypes in temporal cortex of Alzheimer brains.

1 reference

12 December 2020

Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum

1 reference

12 December 2020

Effects of cholinergic depletion on neuron activities in the cat visual cortex.

1 reference

12 December 2020

Effects of cholinergic drugs on learning impairment in ventral globus pallidus-lesioned rats.

1 reference

12 December 2020

Benzodiazepine and beta-carboline interactions with GABAA receptor-gated chloride channels in mammalian cultured spinal cord neurons

1 reference

12 December 2020

Muscarinic and nicotinic cholinergic binding sites in Alzheimer's disease cerebral cortex.

1 reference

12 December 2020

A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, ?-carbolines, and phenobarbitone

1 reference

12 December 2020

Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines

1 reference

12 December 2020

Mechanism of antagonism by physostigmine of acute flunitrazepam intoxication.

1 reference

12 December 2020

Clinical trials with the cholinergic drug RS 86 in Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT)

1 reference

12 December 2020

Microinjection of procaine or GABA into the nucleus basalis magnocellularis affects cue-elicited unit responses in the rat frontal cortex

1 reference

12 December 2020

THA increases action potential duration of central histamine neurons in vitro

1 reference

12 December 2020

Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system

1 reference

12 December 2020

A critique of the vasopressin-memory hypothesis

1 reference

12 December 2020

Ratio of pyramidal cells versus non-pyramidal cells in the human frontal isocortex and changes in ratio with ageing and Alzheimer's disease

1 reference

12 December 2020

Elevations of local cerebral glucose utilization by the beta-carboline ZK 93426.

1 reference

12 December 2020

Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.

1 reference

12 December 2020

Spontaneous exploration of a 6-arm radial tunnel maze by basal forebrain lesioned rats: effects of the benzodiazepine receptor antagonist beta-carboline ZK 93 426.

1 reference

12 December 2020

Oral physostigmine and lecithin improve memory in Alzheimer disease

1 reference

12 December 2020

Analysis of muscarinic receptor concentration and subtypes following lesion of rat substantia innominata

1 reference

12 December 2020

Involvement of M1-muscarinic receptors in the excitation of neocortical neurones by acetylcholine.

1 reference

12 December 2020

Nucleus basalis and thalamic control of neocortical activity in the freely moving rat.

1 reference

12 December 2020

Effect of central stimulants and depressants on mouse brain acetylcholine and choline levels.

1 reference

12 December 2020

GABAergic and cholinergic neurons exhibit high-affinity nerve growth factor binding in rat basal forebrain

1 reference

12 December 2020

Localization of GABAA receptor alpha-subunit mRNAs in relation to receptor subtypes

1 reference

12 December 2020

Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease.

1 reference

12 December 2020

Tetrahydroaminoacridine (THA) in Alzheimer's disease

1 reference

12 December 2020

Measurement of cholinergic drug effects on memory in Alzheimer's disease

1 reference

12 December 2020

Scopolamine and benzodiazepine models of dementia: cross-reversals by Ro 15-1788 and physostigmine.

1 reference

12 December 2020

Neurofibrillary degeneration of cholinergic and noncholinergic neurons of the basal forebrain in Alzheimer's disease

1 reference

12 December 2020

Pharmacological manipulations of the substantia innominata-cortical cholinergic pathway

1 reference

12 December 2020

Partial reversal of ethanol-induced reductions in exploration by two benzodiazepine antagonists (flumazenil and ZK 93426).

1 reference

12 December 2020

Bidirectional nature of benzodiazepine receptor ligands extends to effects on vigilance.

1 reference

12 December 2020

GABAergic modulation of memory with regard to passive avoidance and conditioned suppression task in mice.

1 reference

12 December 2020

Cholinergic projections from the basal forebrain to frontal, parietal, temporal, occipital, and cingulate cortices: A combined fluorescent tracer and acetylcholinesterase analysis

1 reference

12 December 2020

Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation.

1 reference

12 December 2020

Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies

1 reference

12 December 2020

The effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on the acquisition and retention of a conditional visual discrimination: implications for cholinergic hypotheses of learning and memory

1 reference

12 December 2020

Post-training administration of GABAergic antagonists enhances retention of aversively motivated tasks.

1 reference

12 December 2020

Neural projections from nucleus accumbens to globus pallidus, substantia innominata, and lateral preoptic-lateral hypothalamic area: an anatomical and electrophysiological investigation in the rat.

1 reference

12 December 2020

Oral administration of chronic physostigmine does not improve cognitive or mnesic performances in Alzheimer's presenile dementia.

1 reference

12 December 2020

Intralaminar Neurochemical Distributions in Human Midtemporal Cortex: Comparison Between Alzheimer's Disease and the Normal

1 reference

12 December 2020

Generation of cortical event-related slow potentials in the rat involves nucleus basalis cholinergic innervation

1 reference

12 December 2020

The role of the nucleus basalis of Meynert in dementia: review and reconsideration

1 reference

12 December 2020

Effects of nucleus basalis lesions on the muscarinic and nicotinic modulation of [3H]acetylcholine release in the rat cerebral cortex

1 reference

12 December 2020

A comparison of changes in the nucleus basalis and locus caeruleus in Alzheimer's disease

1 reference

12 December 2020

Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: modification by cholinergic drugs

1 reference

12 December 2020

Voltage-clamp analysis of muscarinic excitation in hippocampal neurons

1 reference

12 December 2020

Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons.

1 reference

12 December 2020

Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens

1 reference

12 December 2020

Effect of quinolinic acid in the nucleus basalis magnocellularis on cortical high-affinity choline uptake

1 reference

12 December 2020

beta-Carbolines for Alzheimer's disease?--more evidence, a test of efficacy and some precautions

1 reference

12 December 2020

CGS 8216, a benzodiazepine receptor antagonist, enhances learning and memory in mice.

1 reference

12 December 2020

Enhanced inhibitory avoidance learning produced by post-trial injections of substance P into the basal forebrain.

1 reference

12 December 2020

Alzheimer's disease: choline acetyltransferase activity in brain tissue from clinical and pathological subgroups

1 reference

12 December 2020

Colocalization of gamma-aminobutyric acid and acetylcholinesterase in rodent cortical neurons

1 reference

12 December 2020

Cholinergic modulation of sensory responses in rat primary somatic sensory cortex

1 reference

12 December 2020

Effects of nBM lesions on muscarinic-stimulation of phosphoinositide hydrolysis

1 reference

12 December 2020

Behavioral and neuronal reorganization after unilateral substantia nigra lesions: evidence for increased interhemispheric nigrostriatal projections.

1 reference

12 December 2020

Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease

1 reference

12 December 2020

Brain muscarinic receptor subtypes are differently affected in Alzheimer's disease and Parkinson's disease.

1 reference

12 December 2020

Effects of continuous infusion of cholinergic drugs on memory impairment in rats with basal forebrain lesions

1 reference

12 December 2020

Pharmacological and ionic characterizations of the muscarinic receptors modulating [3H]acetylcholine release from rat cortical synaptosomes.

1 reference

12 December 2020

Effect of hypnotic and anxiolytic agents on regional concentration of acetylcholine in rat brain

1 reference

12 December 2020

Low-dose oral lorazepam administration in Alzheimer subjects and age-matched controls

1 reference

12 December 2020

High density of benzodiazepine binding sites in the substantia innominata of the rat.

1 reference

12 December 2020

Effects of scopolamine and physostigmine on recognition memory in monkeys with ibotenic-acid lesions of the nucleus basalis of Meynert

1 reference

12 December 2020

Cholinergic function and intellectual decline in Alzheimer's disease

1 reference

12 December 2020

Animal models of Alzheimer's disease: experimental cholinergic denervation

1 reference

12 December 2020

Muscimol-scopolamine interactions in the rat brain: a study with 2-deoxy-D-[1-14C]glucose.

1 reference

12 December 2020

Effects of diazepam on blood choline and acetylcholine turnover in brain of mice.

1 reference

12 December 2020

Nucleus basalis magnocellularis lesions: lack of biochemical and immunocytochemical recovery and effect of cholinesterase inhibitors on passive avoidance.

1 reference

12 December 2020

Dendritic changes in the basal nucleus of Meynert and in the diagonal band nucleus in Alzheimer's disease--a quantitative Golgi investigation

1 reference

12 December 2020

Effects of GABA compounds injected into the subpallidal regions of rat brain on nucleus accumbens evoked hyperactivity

1 reference

12 December 2020

Learning and memory deficits after lesions of the nucleus basalis magnocellularis: reversal by physostigmine

1 reference

12 December 2020

Interaction of 9-amino-1,2,3,4-tetrahydroaminoacridine (THA) with human cortical nicotinic and muscarinic receptor binding in vitro

1 reference

12 December 2020

Functional and neurochemical cortical cholinergic impairment following neurotoxic lesions of the nucleus basalis magnocellularis in the rat.

1 reference

12 December 2020

Differential modification of muscarinic cholinergic receptors in the hippocampus of patients with Alzheimer's disease: an autoradiographic study.

1 reference

12 December 2020

The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type

1 reference

12 December 2020

Presynaptic cholinergic dysfunction in patients with dementia.

1 reference

12 December 2020

Utilization of sodium-dependent high affinity choline uptake as a measure of the activity of cholinergic neurons

1 reference

12 December 2020

GABA-immunoreactive synaptic boutons in the rat basal forebrain: comparison of neurons that project to the neocortex with pallidosubthalamic neurons

1 reference

12 December 2020

The beta-carboline derivatives ZK 93426 and FG 7142 fail to precipitate abstinence signs in diazepam-dependent cats.

1 reference

12 December 2020

The effects of intravenous diazepam and hyoscine upon recognition memory

1 reference

12 December 2020

[35S]-t-butylbicyclophosphorothionate binding sites are constituents of the gamma-aminobutyric acid benzodiazepine receptor complex.

1 reference

12 December 2020

Evaluation of the ?-carboline ZK 93 426 as a benzodiazepine receptor antagonist

1 reference

12 December 2020

Comparative effects of quisqualic and ibotenic acid-induced lesions of the substantia innominata and globus pallidus on the acquisition of a conditional visual discrimination: differential effects on cholinergic mechanisms

1 reference

12 December 2020

The effects of the benzodiazepine antagonist Ro 15-1788 on psychophysiological performance and subjective measures in normal subjects.

1 reference

12 December 2020

Effect of bilateral decortication on nerve growth factor content in basal nucleus and neostriatum of adult rat brain

1 reference

12 December 2020

Differential responsivity of mood, behavior, and cognition to cholinergic agents in elderly neuropsychiatric populations

1 reference

12 December 2020

Treatment strategies for senile dementia: antagonist beta-carbolines

1 reference

12 December 2020

Exploratory behavior models of anxiety in mice

1 reference

12 December 2020

Physostigmine improves water maze performance following nucleus basalis magnocellularis lesions in rats

1 reference

12 December 2020

Post-trial hormonal treatment effects: memory modulation or perceptual distortion?

1 reference

12 December 2020

Do passive-avoidance tasks permit assessment of retrograde amnesia in rats?

1 reference

12 December 2020

GABAergic input to cholinergic forebrain neurons: an ultrastructural study using retrograde tracing of HRP and double immunolabeling.

1 reference

12 December 2020

Transmitter deficits in Alzheimer's disease

1 reference

12 December 2020

Acetylcholine produces stimulus-specific receptive field alterations in cat auditory cortex

1 reference

12 December 2020

Topographical distribution of neurochemical changes in Alzheimer's disease

1 reference

12 December 2020

Studies on human memory: The interactions of diazepam, scopolamine, and physostigmine

1 reference

12 December 2020

Cortical muscarinic receptor function following quinolinic acid-induced lesion of the nucleus basalis magnocellularis

1 reference

12 December 2020

Behavioral and neurochemical differentiation of specific projections in the septal-hippocampal cholinergic pathway of the rat

1 reference

12 December 2020

Galanin hyperinnervates surviving neurons of the human basal nucleus of Meynert in dementias of Alzheimer's and Parkinson's disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia.

1 reference

12 December 2020

Radial-arm maze deficits produced by colchicine administered into the area of the nucleus basalis are ameliorated by cholinergic agents

1 reference

12 December 2020

Regional changes in the rate of turnover of acetylcholine in rat brain following diazepam or muscimol.

1 reference

12 December 2020

Basal nucleus of Meynert. A neuropathological study in Alzheimer's disease, simple senile dementia, Pick's disease and Huntington's chorea

1 reference

12 December 2020

Nucleus basalis involvement in conditioned neuronal responses in the rat frontal cortex.

1 reference

12 December 2020

Long-term neuropathological and neurochemical effects of nucleus basalis lesions in the rat.

1 reference

12 December 2020

M-current in human neocortical neurones.

1 reference

12 December 2020

Type I and type II gamma-aminobutyric acid/benzodiazepine receptors: purification and analysis of novel receptor complex from neonatal cortex

1 reference

12 December 2020

Acute effects of oral pyridostigmine on memory and cognitive function in SDAT.

1 reference

12 December 2020

Resolving GABAA/benzodiazepine receptors: cellular and subcellular localization in the CNS with monoclonal antibodies.

1 reference

12 December 2020

Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93,426: preliminary observations on psychotropic activity

1 reference

12 December 2020

Acetylcholine-induced inhibition in the cat visual cortex is mediated by a GABAergic mechanism

1 reference

12 December 2020

Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks

1 reference

12 December 2020

Locomotor hyperactivity in the rat after infusion of muscimol and [D-Ala2]Met-enkephalin into the nucleus basalis magnocellularis. Possible interaction with cortical cholinergic projections

1 reference

12 December 2020

Pilocarpine and physostigmine attenuate spatial memory impairments produced by lesions of the nucleus basalis magnocellularis

1 reference

12 December 2020

Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease.

1 reference

12 December 2020

Heterogeneity of presynaptic muscarinic receptors involved in modulation of transmitter release

1 reference

12 December 2020

Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type.

1 reference

12 December 2020

Effects of selected muscarinic cholinergic antagonists on [3H]acetylcholine release from rat hippocampal slices.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02253710

1 reference

24 August 2017

1 reference

PubMed ID

2160662