(Q37883025)

24 August 2017

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title

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases (English)

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24 August 2017

1

Peter Carmeliet

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24 August 2017

2

Rakesh K Jain

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24 August 2017

1 June 2011

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Nature Reviews Drug Discovery

24 August 2017

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24 August 2017

10

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24 August 2017

417-427

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24 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nrd3455

24 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.

31 March 2020

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31 March 2020

1 reference

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31 March 2020

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

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31 March 2020

1 reference

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31 March 2020

1 reference

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

31 March 2020

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PlGF blockade does not inhibit angiogenesis during primary tumor growth

31 March 2020

1 reference

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Response criteria for glioma

31 March 2020

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Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.

31 March 2020

1 reference

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study

31 March 2020

1 reference

Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer

31 March 2020

1 reference

Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11.

31 March 2020

1 reference

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

31 March 2020

1 reference

Role of placental growth factor in mesenteric neoangiogenesis in a mouse model of portal hypertension.

31 March 2020

1 reference

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2

31 March 2020

1 reference

Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization

31 March 2020

1 reference

Human studies of angiogenic gene therapy

31 March 2020

1 reference

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging

31 March 2020

1 reference

Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide

31 March 2020

1 reference

Scheduling of radiation with angiogenesis inhibitors anginex and Avastin improves therapeutic outcome via vessel normalization.

31 March 2020

1 reference

Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment

31 March 2020

1 reference

Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation

31 March 2020

1 reference

Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks

31 March 2020

1 reference

Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse

31 March 2020

1 reference

12 December 2020

Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors

1 reference

12 December 2020

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

1 reference

12 December 2020

Tumor angiogenesis: therapeutic implications

1 reference

12 December 2020

Monitoring the longitudinal intra-tumor physiological impulse response to VEGFR2 blockade in breast tumors using DCE-CT.

1 reference

12 December 2020

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.

1 reference

12 December 2020

Considerations on blood supply and fluid exchange in tumors

1 reference

12 December 2020

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

1 reference

12 December 2020

Determinants of tumor blood flow: a review

1 reference

12 December 2020

Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche.

1 reference

12 December 2020

In vivo prediction of vascular susceptibility to vascular susceptibility endothelial growth factor withdrawal: magnetic resonance imaging of C6 rat glioma in nude mice.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRD3455

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24 August 2017

1 reference

PubMed ID

21629292