(Q37902049)

25 August 2017

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title

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation (English)

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25 August 2017

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1

Anton Wutz

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25 August 2017

18 July 2011

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25 August 2017

Nature Reviews Genetics

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25 August 2017

12

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25 August 2017

542-553

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25 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrg3035

25 August 2017

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cites work

Gene action in the X-chromosome of the mouse (Mus musculus L.)

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A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis

31 March 2020

1 reference

Characterization of a murine gene expressed from the inactive X chromosome.

31 March 2020

1 reference

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

31 March 2020

1 reference

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

31 March 2020

1 reference

XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure

31 March 2020

1 reference

Xist-deficient mice are defective in dosage compensation but not spermatogenesis

31 March 2020

1 reference

Requirement for Xist in X chromosome inactivation

31 March 2020

1 reference

Regulation of X-chromosome inactivation by the X-inactivation centre.

31 March 2020

1 reference

The human X-inactivation centre is not required for maintenance of X-chromosome inactivation

31 March 2020

1 reference

Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation

31 March 2020

1 reference

A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation

31 March 2020

1 reference

31 March 2020

Chromosome territories

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Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing.

31 March 2020

1 reference

Chromosomal silencing and localization are mediated by different domains of Xist RNA.

31 March 2020

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RNAs templating chromatin structure for dosage compensation in animals

31 March 2020

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PNA interference mapping demonstrates functional domains in the noncoding RNA Xist

31 March 2020

1 reference

Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome

31 March 2020

1 reference

A stable proteinaceous structure in the territory of inactive X chromosomes

31 March 2020

1 reference

Scaffold attachment factor A (SAF-A) is concentrated in inactive X chromosome territories through its RGG domain

31 March 2020

1 reference

The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

31 March 2020

1 reference

The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.

31 March 2020

1 reference

A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced

31 March 2020

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The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences

31 March 2020

1 reference

X-chromosome inactivation: a repeat hypothesis.

31 March 2020

1 reference

Long-range cis effects of ectopic X-inactivation centres on a mouse autosome

31 March 2020

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Genetic analysis of the mouse X inactivation center defines an 80-kb multifunction domain

31 March 2020

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Attenuated spread of X-inactivation in an X;autosome translocation

31 March 2020

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Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation

31 March 2020

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X inactivation-specific methylation of LINE-1 elements by DNMT3B: implications for the Lyon repeat hypothesis.

31 March 2020

1 reference

LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation

31 March 2020

1 reference

Silencing of the mammalian X chromosome

31 March 2020

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Epigenetic dynamics of imprinted X inactivation during early mouse development

31 March 2020

1 reference

Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation

31 March 2020

1 reference

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

31 March 2020

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Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation

31 March 2020

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Role of histone H3 lysine 27 methylation in X inactivation

31 March 2020

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Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells

31 March 2020

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Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing

31 March 2020

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The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation

31 March 2020

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Polycomb complexes act redundantly to repress genomic repeats and genes

31 March 2020

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The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation

31 March 2020

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Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

31 March 2020

1 reference

2-D structure of the A region of Xist RNA and its implication for PRC2 association

31 March 2020

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A chromosomal memory triggered by Xist regulates histone methylation in X inactivation

31 March 2020

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De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation.

31 March 2020

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Loss of methylation activates Xist in somatic but not in embryonic cells

31 March 2020

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Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation

31 March 2020

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SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells

31 March 2020

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Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible

31 March 2020

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An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells

31 March 2020

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SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes.

31 March 2020

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The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1

31 March 2020

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Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.

31 March 2020

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Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

31 March 2020

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Gene body-specific methylation on the active X chromosome

31 March 2020

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

31 March 2020

1 reference

X Inactivation in the Mouse Embryo Deficient for Dnmt1: Distinct Effect of Hypomethylation on Imprinted and Random X Inactivation

31 March 2020

1 reference

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

31 March 2020

1 reference

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

31 March 2020

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A structural-maintenance-of-chromosomes hinge domain-containing protein is required for RNA-directed DNA methylation.

31 March 2020

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Inactive X chromosome-specific reduction in placental DNA methylation

31 March 2020

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Imprinted X inactivation maintained by a mouse Polycomb group gene

31 March 2020

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Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells

31 March 2020

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The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation

31 March 2020

1 reference

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

31 March 2020

1 reference

Mammalian Su(var) genes in chromatin control.

31 March 2020

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The epigenetics of rRNA genes: from molecular to chromosome biology

31 March 2020

1 reference

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

31 March 2020

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The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

31 March 2020

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Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin

31 March 2020

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High-resolution analysis of epigenetic changes associated with X inactivation.

31 March 2020

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Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome

31 March 2020

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Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome

31 March 2020

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Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells.

31 March 2020

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X-Inactivation and histone H4 acetylation in embryonic stem cells

31 March 2020

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Histone macroH2A1.2 relocates to the inactive X chromosome after initiation and propagation of X-inactivation.

31 March 2020

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Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome

31 March 2020

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Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

31 March 2020

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macroH2A1-dependent silencing of endogenous murine leukemia viruses

31 March 2020

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X chromosome activity in mouse XX primordial germ cells

31 March 2020

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X chromosome reactivation initiates in nascent primordial germ cells in mice

31 March 2020

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Reactivation of the paternal X chromosome in early mouse embryos

31 March 2020

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Reversal of X-inactivation in female mouse somatic cells hybridized with murine teratocarcinoma stem cells in vitro

31 March 2020

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Changing potency by spontaneous fusion.

31 March 2020

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

31 March 2020

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Molecular coupling of Xist regulation and pluripotency.

31 March 2020

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The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

31 March 2020

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Molecular coupling of Tsix regulation and pluripotency

31 March 2020

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Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells

31 March 2020

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RNF12 activates Xist and is essential for X chromosome inactivation

31 March 2020

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Klf4 reverts developmentally programmed restriction of ground state pluripotency

31 March 2020

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Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

31 March 2020

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Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer

31 March 2020

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Reversibility of functional deficits in experimental models of Rett syndrome.

31 March 2020

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AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome

31 March 2020

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

31 March 2020

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

31 March 2020

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Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos

31 March 2020

1 reference

The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing

31 March 2020

1 reference

Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation

31 March 2020

1 reference

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

31 March 2020

1 reference

X-inactivation profile reveals extensive variability in X-linked gene expression in females

31 March 2020

1 reference

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development

31 March 2020

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Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus

31 March 2020

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An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta.

31 March 2020

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Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse.

31 March 2020

1 reference

Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis

31 March 2020

1 reference

X chromosome inactivation is initiated in human preimplantation embryos

31 March 2020

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The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene

31 March 2020

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Construction and evolution of imprinted loci in mammals

31 March 2020

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Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic.

31 March 2020

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Specific patterns of histone marks accompany X chromosome inactivation in a marsupial.

31 March 2020

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Key features of the X inactivation process are conserved between marsupials and eutherians.

31 March 2020

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Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation

31 March 2020

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Histone H3 trimethylation at lysine 9 marks the inactive metaphase X chromosome in the marsupial Monodelphis domestica.

31 March 2020

1 reference

Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse

31 March 2020

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Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle

31 March 2020

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

31 March 2020

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Generation of germline-competent induced pluripotent stem cells

31 March 2020

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

31 March 2020

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Direct reprogramming of fibroblasts into epiblast stem cells.

31 March 2020

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Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

31 March 2020

1 reference

X-chromosome activity of the mouse primordial germ cells revealed by the expression of an X-linked lacZ transgene

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21765457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21765457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRG3035

1 reference

25 August 2017

1 reference

PubMed ID

21765457