(Q37913204)

25 August 2017

1 reference

title

The role of glutathione and glutathione transferases in chemical carcinogenesis (English)

1 reference

25 August 2017

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1 reference

Coles B

1

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PubMed ID

2182291

25 August 2017

Ketterer B

series ordinal

2

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25 August 2017

1 January 1990

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Critical Reviews in Biochemistry and Molecular Biology

25 August 2017

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25 August 2017

25

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25 August 2017

47-70

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25 August 2017

1

1 reference

The role of glutathione in detoxication

25 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

An enzyme from rat liver catalysing conjugations with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Histochemical localization of glutathione in tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Effects of modifying structure on electrophilic reactions with biological nucleophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

In vivo and in vitro formation of glutathione conjugates from the K-region epoxides of 1-nitropyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: A stopped-flow kinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The enzymatic conjugation of glutathione with bay-region diol-epoxides of benzo[a]pyrene, benz[a]anthracene and chrysene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione transferases: nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Construction and characterization of a plasmid containing complementary DNA to mRNA encoding the N-terminal amino acid sequence of the rat glutathione transferase Ya subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Cloning and the nucleotide sequence of rat glutathione S-transferase P cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Structural analysis of a rat liver glutathione S-transferase Ya gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The isolation of a fetal rat liver glutathione S-transferase isoenzyme with high glutathione peroxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Isoenzymes of glutathione transferase in rat small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Relative merits of immunohistochemical demonstrations of placental, A, B and C forms of glutathione S-transferase and histochemical demonstration of gamma-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

4-Hydroxyalk-2-enals are substrates for glutathione transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The subunit structure of a major glutathione S-transferase form, MT, in rat testis. Evidence for a heterodimer consisting of subunits with different isoelectric points

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Multiple Forms of Human Glutathione S-Transferase and Their Affinity for Bilirubin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The basic glutathione S-transferases from human livers are products of separate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Human genes for glutathione S-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Liver glutathione S-transferase polymorphism in Japanese and its pharmacogenetic importance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Hereditary interindividual differences in the glutathione transferase activity towards trans-stilbene oxide in resting human mononuclear leukocytes are due to a particular isozyme(s).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Developmental and hormonal regulation of the major form of hepatic glutathione S-transferase in male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Age-associated alterations in hepatic glutathione-S-transferase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Transformation related expression of glutathione-S-transferase P in rat liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

A characteristic electrophoretic pattern of cytosolic polypeptides from hepatocyte nodules generated during liver carcinogenesis in several models.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Expression of class Pi glutathione transferase in human malignant melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Alteration of glutathione transferase isoenzyme concentrations in human renal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Expression of glutathione S-transferase isoenzymes in human small cell lung cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The metabolism of 3-methylcholanthrene and some related compounds by rat-liver homogenates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

K region benzo(α)pyrene-4,5-oxide is conjugated by homogeneous gluthathione S-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Studies on the detoxication of microsomally-activated aflatoxin B1 by glutathione and glutathione transferases in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Inactivation of DNA-binding metabolites of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by glutathione and glutathione S-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione conjugation and DNA-binding of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene and (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in isolated rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Sulphotransferase-mediated covalent binding of the carcinogen 7,12-dihydroxymethylbenz[a]anthracene to calf thymus DNA and its inhibition by glutathione transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione transferases in rat lung: the presence of transferase 7-7, highly efficient in the conjugation of glutathione with the carcinogenic (+)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Stereoselectivity of cytosolic glutathione S-transferases with arene and alkene oxide substrates in various tissues and isolated hepatic and pulmonary cells of the rabbit.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Studies on metabolism and toxicity of styrene--VI. Regioselectivity in glutathione S-conjugation and hydrolysis of racemic, R- and S-phenyloxiranes in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The formation of 2,3-dihydroxy-2,3-dihydro-aflatoxin B1 by the metabolism of aflatoxin B1 by liver microsomes isolated from certain avian and mammalian species and the possible role of this metabolite in the acute toxicity of aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Biological and chemical studies on 8,9-dihydroxy-8,9-dihydro-aflatoxin B1 and some of its esters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The requirement for glutathione S-transferase in the conjugation of activated aflatoxin B1 during aflatoxin hepatocarcinogenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Mechanism of the resistance to cytotoxicity which precedes aflatoxin B1 hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Metabolic basis of the species difference to aflatoxin B1 induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Modulation of microsome-mediated aflatoxin B1 binding to exogenous and endogenous DNA by cytosolic glutathione S-transferases in rat and hamster livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Dietary administration of 2(3)-t-butyl-4-hydroxyanisole elevates mouse liver microsome-mediated DNA binding and mutagenicity of aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Comparative kinetic studies on aflatoxin B1-DNA binding and aflatoxin B1-glutathione conjugation with rat and hamster livers in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The major role of glutathione in the metabolism and excretion of N,N-dimethyl-4-aminoazobenzene in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Mutagenicity and carcinogenicity of nitroarenes and their sources in the environment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Formation of N-(glutathion-S-methylene)-4-aminoazobenzene following metabolic oxidation of the N-methyl group of the carcinogen, N-methyl-4-aminoazobenzene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Characterization and properties of the DNA adducts formed from N-methyl-4-aminoazobenzene in rats during a carcinogenic treatment regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Formation of 3-(glutathion-S-YL)-N-methyl-4-aminoazobenzene and inhibition of aminoazo dye-nucleic acid binding in vitro by reaction of glutathione with metabolically-generated N-methyl-4-aminoazobenzene-N-sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione adducts of N-methyl-4-aminoazobenzene formed in vivo and by reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione conjugate formation in the detoxification of ultimate and proximate carcinogens of N-methyl-4-aminoazobenzene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Identification of glutathione conjugates formed from N-hydroxy-2-acetylaminofluorene in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Reaction of 2-acetylaminofluorene-N-sulfate with RNA and glutathione: evidence for the generation of two reactive intermediates with different reactivities towards RNA and glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Formation and persistence of arylamine DNA adducts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Reactivity of benzidine diimine with DNA to form N-(deoxyguanosin-8-yl)-benzidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Prostaglandin H synthase oxidation of benzidine and o-dianisidine: reduction and conjugation of activated amines by thiols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Identification of the mutagens in cooked beef

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reacion with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Covalent binding of N-hydroxy-Trp-P-2 to DNA by cytosolic proline-dependent system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

DNA binding of N-hydroxy-Trp-P-2 and N-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Activation and detoxication of N-hydroxy-Trp-P-2 by glutathione and glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione conjugation of arylnitroso compound: detection and monitoring labile intermediates in situ inside a fast atom bombardment mass spectrometer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Major routes of metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Tumorigenicity and metabolism of 1-nitropyrene in A/J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The in vitro methylation of DNA by microsomally-activated dimethylnitrosamine and its correlation with formaldehyde production.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Reduced glutathione inhibits the alkylation by N-nitrosodimethylamine of liver DNA in vivo and microsomal fraction in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

Mode of Action of Alkylating Agents: Formation of S-Ethylcysteine from Ethyl Methanesulphonate In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409239009090605

10.3109/10409239009090605

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

2182291