(Q37942354)

25 August 2017

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title

The nucleoskeleton as a genome-associated dynamic 'network of networks'. (English)

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25 August 2017

Dan N Simon

1

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PubMed ID

21971041

25 August 2017

Katherine L Wilson

series ordinal

2

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25 August 2017

5 October 2011

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Nature Reviews Molecular Cell Biology

25 August 2017

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25 August 2017

12

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25 August 2017

695-708

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25 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrm3207

25 August 2017

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cites work

Actin antibody: the specific visualization of actin filaments in non-muscle cells

1 reference

Half a century of "the nuclear matrix"

31 March 2020

1 reference

Nuclear matrix. Isolation and characterization of a framework structure from rat liver nuclei

31 March 2020

1 reference

Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution

31 March 2020

1 reference

The lamin protein family.

31 March 2020

1 reference

A new look at the nuclear matrix

31 March 2020

1 reference

NMPdb: Database of Nuclear Matrix Proteins

31 March 2020

1 reference

The nuclear lamina is a meshwork of intermediate-type filaments

31 March 2020

1 reference

Diseases of the nuclear envelope

31 March 2020

1 reference

The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber.

31 March 2020

1 reference

Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction.

31 March 2020

1 reference

Lamins A and C but not lamin B1 regulate nuclear mechanics.

31 March 2020

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Filaments made from A- and B-type lamins differ in structure and organization.

31 March 2020

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Visualization of replication factories attached to nucleoskeleton

31 March 2020

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Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

31 March 2020

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Mechanotransduction gone awry

31 March 2020

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Viscoelastic properties of the cell nucleus

31 March 2020

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Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove

31 March 2020

1 reference

31 March 2020

Lamin-binding Proteins

1 reference

Human autoantibodies reveal titin as a chromosomal protein

31 March 2020

1 reference

D-Titin: a giant protein with dual roles in chromosomes and muscles

31 March 2020

1 reference

Nuclear functions of actin

31 March 2020

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The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription

31 March 2020

1 reference

Chromokinesins: multitalented players in mitosis

31 March 2020

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Adding pieces to the puzzling plant nuclear envelope

31 March 2020

1 reference

Nuclear spectrin-like proteins are structural actin-binding proteins in plants

31 March 2020

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Change of karyoskeleton during spermatogenesis of Xenopus: expression of lamin LIV, a nuclear lamina protein specific for the male germ line

31 March 2020

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How does the extracellular matrix direct gene expression?

31 March 2020

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Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

31 March 2020

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Coupling of the nucleus and cytoplasm: role of the LINC complex

31 March 2020

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LINC complexes in health and disease

31 March 2020

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Nesprins LINC the nucleus and cytoskeleton

31 March 2020

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The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton

31 March 2020

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Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy.

31 March 2020

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Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis

31 March 2020

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Nesprin isoforms: are they inside or outside the nucleus?

31 March 2020

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Mammalian sperm head formation involves different polarization of two novel LINC complexes

31 March 2020

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Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.

31 March 2020

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Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.

31 March 2020

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A molecular mechanism underlying the neural-specific defect in torsinA mutant mice

31 March 2020

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TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton

31 March 2020

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LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutation

31 March 2020

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The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component.

31 March 2020

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The nuclear pore complex: bridging nuclear transport and gene regulation

31 March 2020

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Functional association of Sun1 with nuclear pore complexes

31 March 2020

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POM121 and Sun1 play a role in early steps of interphase NPC assembly

31 March 2020

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Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex

31 March 2020

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Incorporation of the nuclear pore basket protein nup153 into nuclear pore structures is dependent upon lamina assembly: evidence from cell-free extracts of Xenopus eggs

31 March 2020

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Sequence preference in RNA recognition by the nucleoporin Nup153.

31 March 2020

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Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

31 March 2020

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Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms

31 March 2020

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Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153.

31 March 2020

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Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility.

31 March 2020

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Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

31 March 2020

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The nuclear basket of the nuclear pore complex is part of a higher-order filamentous network that is related to chromatin.

31 March 2020

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Intranuclear filaments containing a nuclear pore complex protein.

31 March 2020

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Actin- and protein-4.1-containing filaments link nuclear pore complexes to subnuclear organelles in Xenopus oocyte nuclei.

31 March 2020

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Nuclear myosin 1 is in complex with mature rRNA transcripts and associates with the nuclear pore basket.

31 March 2020

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Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments

31 March 2020

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Amino acid substitutions of coiled-coil protein Tpr abrogate anchorage to the nuclear pore complex but not parallel, in-register homodimerization

31 March 2020

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The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR.

31 March 2020

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Visualization of a highly organized intranuclear network of filaments in living mammalian cells.

31 March 2020

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Assembly and transport of a premessenger RNP particle

31 March 2020

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Small ribosomal subunits associate with nuclear myosin and actin in transit to the nuclear pores.

31 March 2020

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EAST interacts with Megator and localizes to the putative spindle matrix during mitosis in Drosophila.

31 March 2020

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Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome

31 March 2020

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DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery

31 March 2020

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Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

31 March 2020

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Protein-protein interactions between human nuclear lamins expressed in yeast

31 March 2020

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The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

31 March 2020

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Chromatin: linking structure and function in the nucleolus

31 March 2020

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Lamin B1 maintains the functional plasticity of nucleoli

31 March 2020

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The supramolecular organization of the C. elegans nuclear lamin filament

31 March 2020

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Isolation, characterization, and in vitro assembly of intermediate filaments.

31 March 2020

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Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior.

31 March 2020

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The nuclear envelope at a glance

31 March 2020

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Lamina-independent lamins in the nuclear interior serve important functions

31 March 2020

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Lamina-associated Polypeptide 2-α Forms Homo-trimers via Its C Terminus, and Oligomerization Is Unaffected by a Disease-causing Mutation

31 March 2020

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The nuclear envelope can control gene expression and cell cycle progression via miRNA regulation.

31 March 2020

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Role of A-type lamins in signaling, transcription, and chromatin organization.

31 March 2020

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Physical plasticity of the nucleus in stem cell differentiation

31 March 2020

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Lamin a truncation in Hutchinson-Gilford progeria.

31 March 2020

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

31 March 2020

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Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome

31 March 2020

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Molecular signatures of Emery-Dreifuss muscular dystrophy

31 March 2020

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TMEM43 mutations in Emery-Dreifuss muscular dystrophy-related myopathy

31 March 2020

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Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy

31 March 2020

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LUMA interacts with emerin and influences its distribution at the inner nuclear membrane

31 March 2020

1 reference

108th ENMC International Workshop, 3rd Workshop of the MYO-CLUSTER project: EUROMEN, 7th International Emery-Dreifuss Muscular Dystrophy (EDMD) Workshop, 13-15 September 2002, Naarden, The Netherlands

31 March 2020

1 reference

Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells

31 March 2020

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SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton

31 March 2020

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Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro

31 March 2020

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Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

31 March 2020

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Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy

31 March 2020

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Direct interaction between emerin and lamin A

31 March 2020

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Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane

31 March 2020

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An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.

31 March 2020

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Emerin and the nuclear lamina in muscle and cardiac disease.

31 March 2020

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

31 March 2020

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Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery Dreifuss muscular dystrophy

31 March 2020

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Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope.

31 March 2020

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Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases

31 March 2020

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Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes

31 March 2020

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Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

31 March 2020

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The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells

31 March 2020

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Lamin B1 is required for mouse development and nuclear integrity

31 March 2020

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Cell nuclei spin in the absence of lamin b1.

31 March 2020

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Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.

31 March 2020

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Differential expression of nuclear lamin, the major component of nuclear lamina, during neurogenesis in two germinal regions of adult rat brain

31 March 2020

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Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

31 March 2020

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NuMA after 30 years: the matrix revisited.

31 March 2020

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Silencing of Nuclear Mitotic Apparatus protein (NuMA) accelerates the apoptotic disintegration of the nucleus

31 March 2020

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NuMA influences higher order chromatin organization in human mammary epithelium

31 March 2020

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Induction of a regular nuclear lattice by overexpression of NuMA

31 March 2020

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Evolution of spectrin function in cytoskeletal and membrane networks

31 March 2020

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Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains

31 March 2020

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Ultrastructural localization of actin and actin-binding proteins in the nucleus

31 March 2020

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Spectrin repeat proteins in the nucleus.

31 March 2020

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A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix

31 March 2020

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Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice

31 March 2020

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alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus

31 March 2020

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Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links

31 March 2020

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Knockdown of alphaII spectrin in normal human cells by siRNA leads to chromosomal instability and decreased DNA interstrand cross-link repair.

31 March 2020

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Nuclear actin and protein 4.1: essential interactions during nuclear assembly in vitro.

31 March 2020

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Inhibition of protein 4.1 R and NuMA interaction by mutagenization of their binding-sites abrogates nuclear localization of 4.1 R.

31 March 2020

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Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling

31 March 2020

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Direct actin binding to A- and B-type lamin tails and actin filament bundling by the lamin A tail

31 March 2020

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Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

31 March 2020

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Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope

31 March 2020

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Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus

31 March 2020

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An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments.

31 March 2020

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Cardiac titin: structure, functions and role in disease

31 March 2020

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Nuclear titin interacts with A- and B-type lamins in vitro and in vivo

31 March 2020

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Nuclear localization of the titin Z1Z2Zr domain and role in regulating cell proliferation

31 March 2020

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Actin: from structural plasticity to functional diversity.

31 March 2020

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Cell and molecular biology of nuclear actin.

31 March 2020

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Actin complexes in the cell nucleus: new stones in an old field

31 March 2020

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Actin dynamics and functions in the interphase nucleus: moving toward an understanding of nuclear polymeric actin

31 March 2020

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Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin

31 March 2020

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Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

31 March 2020

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Depletion of nuclear actin is a key mediator of quiescence in epithelial cells

31 March 2020

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Bacterial DNA segregation by the actin-like MreB protein.

31 March 2020

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Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells

31 March 2020

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Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes

31 March 2020

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A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes

31 March 2020

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Nucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations.

31 March 2020

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Probing actin polymerization by intermolecular cross-linking

31 March 2020

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Crystal structure of polymerization-competent actin

31 March 2020

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SUMOylation of nuclear actin

31 March 2020

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Mechanisms underlying intranuclear rod formation.

31 March 2020

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A comparative study of Drosophila and human A-type lamins

31 March 2020

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Moving chromatin within the interphase nucleus-controlled transitions?

31 March 2020

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Long-range directional movement of an interphase chromosome site

31 March 2020

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Actin-dependent intranuclear repositioning of an active gene locus in vivo.

31 March 2020

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Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolution.

31 March 2020

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A myosin I isoform in the nucleus

31 March 2020

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From transcription to transport: emerging roles for nuclear myosin I.

31 March 2020

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An actin-myosin complex on actively transcribing genes.

31 March 2020

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Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts

31 March 2020

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Nuclear actin and myosin I are required for RNA polymerase I transcription.

31 March 2020

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Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II.

31 March 2020

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Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners

31 March 2020

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A novel role of the actin-nucleating Arp2/3 complex in the regulation of RNA polymerase II-dependent transcription

31 March 2020

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p53-cofactor JMY is a multifunctional actin nucleation factor

31 March 2020

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Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription

31 March 2020

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Myosin-1c, the hair cell's adaptation motor

31 March 2020

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Myosin VI rewrites the rules for myosin motors

31 March 2020

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Nuclear myosin VI enhances RNA polymerase II-dependent transcription

31 March 2020

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Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses

31 March 2020

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Myosin VI is a mediator of the p53-dependent cell survival pathway.

31 March 2020

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Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners

31 March 2020

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Myosin V from head to tail

31 March 2020

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Myosin Vb localises to nucleoli and associates with the RNA polymerase I transcription complex.

31 March 2020

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Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II.

31 March 2020

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Myosin Va phosphorylated on Ser1650 is found in nuclear speckles and redistributes to nucleoli upon inhibition of transcription

31 March 2020

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Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity

31 March 2020

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Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression

31 March 2020

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Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation

31 March 2020

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MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer

31 March 2020

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Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species

31 March 2020

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Ancient animal ancestry for nuclear myosin

31 March 2020

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Subnuclear compartmentalization and function of actin and nuclear Myosin I in plants

31 March 2020

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Kinesin superfamily motor proteins and intracellular transport

31 March 2020

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Human chromokinesin KIF4A functions in chromosome condensation and segregation

31 March 2020

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A novel role of the chromokinesin Kif4A in DNA damage response

31 March 2020

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KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

31 March 2020

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The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles

31 March 2020

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A functional relationship between NuMA and kid is involved in both spindle organization and chromosome alignment in vertebrate cells

31 March 2020

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PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity

31 March 2020

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Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK.

31 March 2020

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CREM-dependent transcription in male germ cells controlled by a kinesin.

31 March 2020

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The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1

31 March 2020

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SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells

31 March 2020

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SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis

31 March 2020

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Overexpression of SATB1 in laryngeal squamous cell carcinoma.

31 March 2020

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SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression

31 March 2020

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Down-regulated expression of SATB2 is associated with metastasis and poor prognosis in colorectal cancer

31 March 2020

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Disassembly of the nucleus in mitotic extracts: membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

31 March 2020

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Barrier-to-autointegration factor is required to segregate and enclose chromosomes within the nuclear envelope and assemble the nuclear lamina

31 March 2020

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MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans

31 March 2020

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Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly

31 March 2020

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A contractile nuclear actin network drives chromosome congression in oocytes

31 March 2020

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SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.

31 March 2020

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Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope

31 March 2020

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A membranous spindle matrix orchestrates cell division

31 March 2020

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Do nuclear envelope and intranuclear proteins reorganize during mitosis to form an elastic, hydrogel-like spindle matrix?

31 March 2020

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Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator

31 March 2020

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Chromator is required for proper microtubule spindle formation and mitosis in Drosophila.

31 March 2020

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Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function

31 March 2020

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Fission yeast cells undergo nuclear division in the absence of spindle microtubules

31 March 2020

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Reorganization of the nuclear envelope during open mitosis

31 March 2020

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Wild-type p53 protein shows calcium-dependent binding to F-actin

31 March 2020

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NUANCE, a giant protein connecting the nucleus and actin cytoskeleton

31 March 2020

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12 December 2020

Further considerations on the intranuclear distribution of HMGI/Y proteins.

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12 December 2020

Experimental observations of a nuclear matrix

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12 December 2020

A Drosophila Tpr protein homolog is localized both in the extrachromosomal channel network and to nuclear pore complexes.

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12 December 2020

Nuclear envelope breakdown in mammalian cells involves stepwise lamina disassembly and microtubule-drive deformation of the nuclear membrane

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12 December 2020

The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development

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12 December 2020

Identification of essential genes in cultured mammalian cells using small interfering RNAs.

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12 December 2020

Protein 4.1, a component of the erythrocyte membrane skeleton and its related homologue proteins forming the protein 4.1/FERM superfamily.

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12 December 2020

NuMA: a nuclear protein involved in mitotic centrosome function

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12 December 2020

mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope

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12 December 2020

The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription

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12 December 2020

Phosphorylation of the nuclear lamins during interphase and mitosis

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12 December 2020

The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation

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12 December 2020

Titin diversity--alternative splicing gone wild

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12 December 2020

Nuclear proteins of the bovine esophageal epithelium. II. The NuMA gene gives rise to multiple mRNAs and gene products reactive with monoclonal antibody W1

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12 December 2020

Identifiers

DOI

10.1038/NRM3207

1 reference

25 August 2017

1 reference

PubMed ID

21971041