(Q37995676)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters (English)

1 reference

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26 January 2020

3

1 reference

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26 January 2020

2

Jurgen Venitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Aditi Mulgaonkar

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

22 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Metabolism & Toxicology

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

553-569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

Quinolone generations: natural history or natural selection?

26 January 2020

cites work

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21 January 2018

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New uses for new and old quinolones and the challenge of resistance

21 January 2018

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Safety of fluoroquinolones: An update

21 January 2018

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Clinical toxicological aspects of fluoroquinolones

21 January 2018

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Fluoroquinolones in the elderly: safety considerations

21 January 2018

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Fluoroquinolone-associated tendinopathy: a critical review of the literature

21 January 2018

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Pharmacokinetics of ciprofloxacin after oral and parenteral administration

21 January 2018

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Pharmacokinetics and metabolism of intravenous and oral fleroxacin in subjects with normal and impaired renal function and in patients on continuous ambulatory peritoneal dialysis

21 January 2018

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Clinical pharmacokinetics of sparfloxacin

21 January 2018

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The clinical pharmacokinetics of levofloxacin

21 January 2018

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Renal handling of fleroxacin in rabbits, dogs, and humans

21 January 2018

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Pharmacokinetics and pharmacodynamics of newer fluoroquinolones

21 January 2018

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Clinical role of protein binding of quinolones

21 January 2018

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Microbiology of newer fluoroquinolones: focus on respiratory pathogens

21 January 2018

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Persistence of Salmonellae in Blood and Bone Marrow: Randomized Controlled Trial Comparing Ciprofloxacin and Chloramphenicol Treatments against Enteric Fever

21 January 2018

1 reference

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Penetration of ciprofloxacin into human cerebrospinal fluid in patients with inflamed and non-inflamed meninges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Mechanisms of action of antimicrobials: focus on fluoroquinolones

21 January 2018

1 reference

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Quinolone antimicrobial agents

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Fluoroquinolone efflux mediated by ABC transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Fluoroquinolone antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Selective role of sulfotransferase 2A1 (SULT2A1) in the N-sulfoconjugation of quinolone drugs in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Comparative pharmacokinetics of ciprofloxacin and temafloxacin in humans: a review

21 January 2018

1 reference

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Intestinal elimination of sparfloxacin, fleroxacin, and ciprofloxacin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Effects of oral cimetidine or ranitidine on the pharmacokinetics of intravenous enoxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Single- and multiple-dose pharmacokinetics of AM-1155, a new 6-fluoro-8-methoxy quinolone, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Effect of probenecid on the distribution and elimination of ciprofloxacin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

New quinolone antibiotics: a survey of the literature from 2005 to 2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Mechanism of renal excretion of AM-715, a new quinolonecarboxylic acid derivative, in rabbits, dogs, and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of enoxacin and its penetration into bronchial secretions and lung tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Transport of levofloxacin in the OK kidney epithelial cell line: interaction with p-aminohippurate transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Human ATP-binding cassette (ABC) transporter family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Analysis and update of the human solute carrier (SLC) gene superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Organic anion transporter (Slc22a) family members as mediators of toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Molecular and cellular physiology of renal organic cation and anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Interactions of fluoroquinolone antibacterials, DX-619 and levofloxacin, with creatinine transport by renal organic cation transporter hOCT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

The molecular biology of renal organic anion and organic cation transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases systemic exposure to ciprofloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Identification of influx transporter for the quinolone antibacterial agent levofloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Human renal organic anion transporter 4 operates as an asymmetric urate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

The multidrug efflux protein NorM is a prototype of a new family of transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Functional characterization of multidrug and toxin extrusion protein 1 as a facilitative transporter for fluoroquinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetic profiles of ciprofloxacin after single intravenous and oral doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of ciprofloxacin in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Ciprofloxacin pharmacokinetics in patients with normal and impaired renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Enantioselective disposition of ofloxacin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of ofloxacin after parenteral and oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

A dose-escalation study of the safety, tolerability, and pharmacokinetics of intravenous gatifloxacin in healthy adult men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Influence of activated charcoal on the pharmacokinetics of moxifloxacin following intravenous and oral administration of a 400 mg single dose to healthy males

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics and tissue penetration of orally administered lomefloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of lomefloxacin in healthy volunteers: comparison of 400 milligrams once daily and 200 milligrams twice daily given orally for 5 days

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Safety and pharmacokinetics of multiple 750-milligram doses of intravenous levofloxacin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics and tolerability of gemifloxacin (SB-265805) after administration of single oral doses to healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Multiple-dose pharmacokinetics and safety of oral amifloxacin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of temafloxacin in humans after multiple oral doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Temafloxacin pharmacokinetics in subjects with normal and impaired renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Multiple-dose pharmacokinetics and safety of rufloxacin in normal volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Pharmacokinetics of sparfloxacin in healthy volunteers and patients: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Effect of probenecid on the kinetics of a single oral 400mg dose of moxifloxacin in healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Effect of Cimetidine on the Pharmacokinetics of Temafloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

Plasma Protein Binding of Gyrase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.674512

10.1517/17425255.2012.674512

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435536%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference