(Q38057689)

27 August 2017

title

Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance (English)

1 reference

27 August 2017

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Eric W-F Lam

2

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author name string

Fung Zhao

series ordinal

1

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27 August 2017

publication date

3 November 2012

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27 August 2017

published in

Frontiers of medicine

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27 August 2017

volume

6

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27 August 2017

issue

4

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27 August 2017

page(s)

376-380

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

27 August 2017

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Many forks in the path: cycling with FoxO.

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FOXO transcription factors: key regulators of cell fate

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A role for menstruation in preconditioning the uterus for successful pregnancy.

21 January 2018

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

21 January 2018

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Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.

21 January 2018

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Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

21 January 2018

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The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression

21 January 2018

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Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer

21 January 2018

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The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells

21 January 2018

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FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

21 January 2018

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FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1.

21 January 2018

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Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

21 January 2018

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FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells

21 January 2018

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Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin

21 January 2018

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Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data

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Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy

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Induction of human epithelial stem/progenitor expansion by FOXM1

21 January 2018

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FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis

21 January 2018

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FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors

21 January 2018

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Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

21 January 2018

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FoxM1 is required for execution of the mitotic programme and chromosome stability

21 January 2018

1 reference

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Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer

21 January 2018

1 reference

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FOXM1 confers acquired cisplatin resistance in breast cancer cells

21 January 2018

1 reference

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ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance

21 January 2018

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The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.

21 January 2018

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Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes

21 January 2018

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FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair.

21 January 2018

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FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance

21 January 2018

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The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells

21 January 2018

1 reference

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ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer

21 January 2018

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FOXM1: From cancer initiation to progression and treatment.

21 January 2018

1 reference

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FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.

21 January 2018

1 reference

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FOXO and FOXM1 in Cancer: The FOXO-FOXM1 Axis Shapes the Outcome of Cancer Chemotherapy

21 January 2018

1 reference

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21 January 2018

1 reference

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FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23124885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23124885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

FoxM1: at the crossroads of ageing and cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23124885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11684-012-0228-0

1 reference

Dimensions Publication ID

27 August 2017

1018577599

0 references

1 reference