(Q38069197)

28 August 2017

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title

Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin-angiotensin system (English)

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28 August 2017

Stuart A Nicklin

5

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author name string

Carolyn Clarke

1

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28 August 2017

Monica Flores-Muñoz

2

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28 August 2017

Clare A McKinney

3

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28 August 2017

Graeme Milligan

4

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28 August 2017

publication date

1 January 2013

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28 August 2017

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28 August 2017

volume

9

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28 August 2017

issue

1

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28 August 2017

page(s)

23-38

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A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

28 August 2017

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Emerging drugs which target the renin-angiotensin-aldosterone system

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ACE2 of the heart: From angiotensin I to angiotensin (1-7)

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Angiotensin-converting enzyme 2 is an essential regulator of heart function

21 January 2018

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Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction

21 January 2018

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Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2.

21 January 2018

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Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins

21 January 2018

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Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

21 January 2018

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Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate

21 January 2018

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A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11.

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Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulation

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Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats

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Lifetime overproduction of circulating Angiotensin-(1-7) attenuates deoxycorticosterone acetate-salt hypertension-induced cardiac dysfunction and remodeling.

21 January 2018

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Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases

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Circulating rather than cardiac angiotensin-(1-7) stimulates cardioprotection after myocardial infarction.

21 January 2018

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Renin-Angiotensin-aldosterone system in diabetes and hypertension

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21 January 2018

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Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction

21 January 2018

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Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.

21 January 2018

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Angiotensin (1-7) prevent heart dysfunction and left ventricular remodeling caused by renal dysfunction in 5/6 nephrectomy mice

21 January 2018

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Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.

21 January 2018

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Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.

21 January 2018

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21 January 2018

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Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats

21 January 2018

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21 January 2018

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21 January 2018

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Products of angiotensin I hydrolysis by human cardiac enzymes potentiate bradykinin

21 January 2018

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Enhancement of bradykinin and resensitization of its B2 receptor.

21 January 2018

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Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor

21 January 2018

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Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension

21 January 2018

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Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor

21 January 2018

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Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice

21 January 2018

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The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy

21 January 2018

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Differential mechanisms of ang (1-7)-mediated vasodepressor effect in adult and aged candesartan-treated rats

21 January 2018

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Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.

21 January 2018

1 reference

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.

21 January 2018

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Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats

21 January 2018

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Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.

21 January 2018

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Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis

21 January 2018

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Genetic Ace2 deficiency accentuates vascular inflammation and atherosclerosis in the ApoE knockout mouse.

21 January 2018

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Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration

21 January 2018

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Angiotensin-(1-7) attenuates neointimal formation after stent implantation in the rat.

21 January 2018

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Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.

21 January 2018

1 reference

AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation

21 January 2018

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Short-term angiotensin(1-7) receptor MAS stimulation improves endothelial function in normotensive rats

21 January 2018

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Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways.

21 January 2018

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Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.

21 January 2018

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Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

21 January 2018

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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

21 January 2018

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ACE2 activation promotes antithrombotic activity

21 January 2018

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Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction.

21 January 2018

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Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studies

21 January 2018

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An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect

21 January 2018

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Beneficial effects of long-term administration of an oral formulation of Angiotensin-(1-7) in infarcted rats

21 January 2018

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The effect of the thioether-bridged, stabilized Angiotensin-(1-7) analogue cyclic ang-(1-7) on cardiac remodeling and endothelial function in rats with myocardial infarction.

21 January 2018

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Oral and pulmonary delivery of thioether-bridged angiotensin-(1-7).

21 January 2018

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Phase I and pharmacokinetic study of angiotensin-(1-7), an endogenous antiangiogenic hormone

21 January 2018

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Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor

21 January 2018

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Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors.

21 January 2018

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Accelerated recovery from irradiation injury by angiotensin peptides

21 January 2018

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Phase I/II dose escalation study of angiotensin 1-7 [A(1-7)] administered before and after chemotherapy in patients with newly diagnosed breast cancer

21 January 2018

1 reference

Pharmacological effects of AVE 0991, a nonpeptide angiotensin-(1-7) receptor agonist

21 January 2018

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The angiotensin-(1-7) receptor agonist AVE0991 is cardioprotective in diabetic rats

21 January 2018

1 reference

Impairment of cardiac function and remodeling induced by myocardial infarction in rats are attenuated by the nonpeptide angiotensin-(1-7) analog AVE 0991.

21 January 2018

1 reference

Discovery and validation of novel peptide agonists for G-protein-coupled receptors.

21 January 2018

1 reference

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

21 January 2018

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A nonpeptide angiotensin II type 2 receptor agonist does not attenuate postmyocardial infarction left ventricular remodeling in mice

21 January 2018

1 reference

Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats

21 January 2018

1 reference

Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling.

21 January 2018

1 reference

Oligomerisation of angiotensin receptors: novel aspects in disease and drug therapy

21 January 2018

1 reference

Interaction of angiotensin II type 1 and D5 dopamine receptors in renal proximal tubule cells

21 January 2018

1 reference

AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.

21 January 2018

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G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor

21 January 2018

1 reference

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS

21 January 2018

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The angiotensin II AT2 receptor is an AT1 receptor antagonist.

21 January 2018

1 reference

Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors

21 January 2018

1 reference

Characterization of a new angiotensin antagonist selective for angiotensin-(1–7): Evidence that the actions of angiotensin-(1–7) are mediated by specific angiotensin receptors

21 January 2018

1 reference

The renin–angiotensin system and diabetes: An update

21 January 2018

1 reference

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

21 January 2018

1 reference

Molecular Mechanisms Involved in the Angiotensin-(1-7)/Mas Signaling Pathway in Cardiomyocytes

21 January 2018

1 reference

Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat

21 January 2018

1 reference

Vascular Relaxation, Antihypertensive Effect, and Cardioprotection of a Novel Peptide Agonist of the Mas Receptor

21 January 2018

1 reference

Angiotensin-converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesions

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FCA.12.75

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28 August 2017

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