(Q38089909)

English

Drug target central

scientific article published on August 2009

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scholarly article

1 reference

Europe PubMed Central

28 August 2017

Drug target central (English)

1 reference

Europe PubMed Central

28 August 2017

1

1 reference

Europe PubMed Central

28 August 2017

object named as

Anna Gaulton

2

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language of work or name

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publication date

1 August 2009

1 reference

Europe PubMed Central

28 August 2017

Expert Opinion on Drug Discovery

1 reference

Europe PubMed Central

28 August 2017

4

1 reference

Europe PubMed Central

28 August 2017

857-872

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Europe PubMed Central

28 August 2017

8

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Europe PubMed Central

28 August 2017

Target discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Genetics of gene expression and its effect on disease

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Literature mining in support of drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

The application of systems biology to drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

High-throughput electronic biology: mining information for drug discovery

1 reference

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21 January 2018

Target discovery from data mining approaches

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

How many genomics targets can a portfolio afford?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Drugs, their targets and the nature and number of drug targets

1 reference

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21 January 2018

Therapeutic targets: progress of their exploration and investigation of their characteristics.

1 reference

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21 January 2018

The druggable genome

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

1 reference

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21 January 2018

A small molecule that binds Hedgehog and blocks its signaling in human cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

How many drug targets are there?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

The druggable genome: an update

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Properties and identification of human protein drug targets.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Prediction of potential drug targets based on simple sequence properties

1 reference

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21 January 2018

Meta-basic estimates the size of druggable human genome.

1 reference

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21 January 2018

Prioritizing the proteome: identifying pharmaceutically relevant targets

1 reference

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21 January 2018

PDTD: a web-accessible protein database for drug target identification

1 reference

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21 January 2018

Network pharmacology: the next paradigm in drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Druggability of human disease genes.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Computational prediction of human metabolic pathways from the complete human genome

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

The PANTHER database of protein families, subfamilies, functions and pathways

1 reference

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21 January 2018

BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009

1 reference

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21 January 2018

ChEBI: a database and ontology for chemical entities of biological interest

1 reference

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21 January 2018

STITCH: interaction networks of chemicals and proteins

1 reference

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21 January 2018

KEGG Atlas mapping for global analysis of metabolic pathways

1 reference

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21 January 2018

Database resources of the National Center for Biotechnology Information

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

HMDB: a knowledgebase for the human metabolome

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Genomic-scale prioritization of drug targets: the TDR Targets database

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Differential splicing, disease and drug targets.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Human cyclooxygenase-1b is not the elusive target of acetaminophen.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Acetaminophen and the cyclooxygenase-3 puzzle: sorting out facts, fictions, and uncertainties

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Comments on "acetaminophen and the cyclooxygenase-3 puzzle: sorting out facts, fictions, and uncertainties".

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

The apparent cooperativity of some GPCRs does not necessarily imply dimerization.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

How and why do GPCRs dimerize?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Estimating the size of the human interactome

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Predicting druggable binding sites at the protein-protein interface.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Nucleic acids as therapeutic agents

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Harnessing bioinformatics to discover new vaccines

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Searching the Tritryp genomes for drug targets

1 reference

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21 January 2018

A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore

1 reference

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21 January 2018

Olfactory receptor gene repertoires in mammals

1 reference

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21 January 2018

A signature of evolutionary constraint on a subset of ectopically expressed olfactory receptor genes

1 reference

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21 January 2018

Identification of the platelet ADP receptor targeted by antithrombotic drugs

1 reference

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21 January 2018

Competitive intelligence and patent analysis in drug discovery

1 reference

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21 January 2018

Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1.

1 reference

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21 January 2018

Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities

1 reference

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21 January 2018

New insights into chemical biology from ORFeome libraries

1 reference

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21 January 2018

Data growth and its impact on the SCOP database: new developments

1 reference

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21 January 2018

InterPro: the integrative protein signature database

1 reference

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21 January 2018

PROTCOM: searchable database of protein complexes enhanced with domain-domain structures

1 reference

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21 January 2018

PINdb: a database of nuclear protein complexes from human and yeast.

1 reference

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21 January 2018

MIPS: analysis and annotation of proteins from whole genomes in 2005.

1 reference

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21 January 2018

Druggable targets and targeted drugs: enhancing the development of new therapeutics

1 reference

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21 January 2018

Computational analysis of ligand relationships within target families

1 reference

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21 January 2018

Chemogenomics approaches to novel target discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Chemogenomics: structuring the drug discovery process to gene families.

1 reference

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21 January 2018

Chemogenomic approaches to drug discovery: similar receptors bind similar ligands

1 reference

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21 January 2018

Chemogenomics and biotechnology

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Global mapping of pharmacological space

1 reference

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21 January 2018

A ligand-based approach to mining the chemogenomic space of drugs

1 reference

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21 January 2018

Relating protein pharmacology by ligand chemistry

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

A chemogenomic analysis of the human proteome: application to enzyme families

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Ligand-based approach to in silico pharmacology: nuclear receptor profiling

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Biological spectra analysis: Linking biological activity profiles to molecular structure

1 reference

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21 January 2018

Systems chemical biology

1 reference

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21 January 2018

Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis.

1 reference

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21 January 2018

Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

1 reference

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21 January 2018

Old drugs--new uses

1 reference

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21 January 2018

A chemical approach to stem cell biology

1 reference

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21 January 2018

New uses for old drugs

1 reference

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21 January 2018

Finding new tricks for old drugs: an efficient route for public-sector drug discovery

1 reference

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21 January 2018

Selective optimization of side activities: another way for drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Systematic discovery of multicomponent therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug

1 reference

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21 January 2018

Generating hypotheses by discovering implicit associations in the literature: a case report of a search for new potential therapeutic uses for thalidomide

1 reference

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21 January 2018

IDMap: facilitating the detection of potential leads with therapeutic targets.

1 reference

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21 January 2018

cAMP detection methods in HTS: selecting the best from the rest

1 reference

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21 January 2018

Integrating scientific data for drug discovery and development using the Life Sciences Grid

1 reference

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21 January 2018

Novel web-based tools combining chemistry informatics, biology and social networks for drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration

1 reference

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21 January 2018

ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr

1 reference

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21 January 2018

DrugBank: a comprehensive resource for in silico drug discovery and exploration

1 reference

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21 January 2018

Post-translational modification of proteins and the discovery of new medicine

1 reference

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21 January 2018

The protein kinase complement of the human genome

1 reference

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21 January 2018

Role of HDAC2 in the pathophysiology of COPD.

1 reference

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21 January 2018

p53 methylation--the Arg-ument is clear

1 reference

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21 January 2018

Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit

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21 January 2018

NetAcet: prediction of N-terminal acetylation sites

1 reference

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21 January 2018

NetworKIN: a resource for exploring cellular phosphorylation networks

1 reference

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21 January 2018

MeMo: a web tool for prediction of protein methylation modifications.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903049290

21 January 2018

dbPTM: an information repository of protein post-translational modification

1 reference

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21 January 2018

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation

1 reference

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21 January 2018

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

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21 January 2018

The Molecular Basis of Predicting Druggability

1 reference

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21 January 2018

Identifiers

10.1517/17460440903049290

1 reference

Europe PubMed Central

28 August 2017

1 reference

Europe PubMed Central

28 August 2017

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