(Q38104753)

28 August 2017

title

Cholera: pathophysiology and emerging therapeutic targets (English)

1 reference

28 August 2017

0 references

1 reference

Chatchai Muanprasat

1

1 reference

28 August 2017

Varanuj Chatsudthipong

series ordinal

2

1 reference

28 August 2017

publication date

1 May 2013

1 reference

Future Medicinal Chemistry

28 August 2017

published in

1 reference

28 August 2017

volume

5

1 reference

28 August 2017

issue

7

1 reference

28 August 2017

page(s)

781-798

1 reference

28 August 2017

1 reference

Antibiotics for both moderate and severe cholera

21 January 2018

1 reference

ENSO and cholera: a nonstationary link related to climate change?

21 January 2018

1 reference

Environmental signatures associated with cholera epidemics

21 January 2018

1 reference

The costs of climate change: a study of cholera in Tanzania

21 January 2018

1 reference

Getting serious about cholera

21 January 2018

1 reference

Developing novel antisecretory drugs to treat infectious diarrhea

21 January 2018

1 reference

Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

Field trial of inactivated oral cholera vaccines in Bangladesh: results from 5 years of follow-up

21 January 2018

1 reference

Effectiveness of mass oral cholera vaccination in Beira, Mozambique

21 January 2018

1 reference

A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India

21 January 2018

1 reference

Field trial of a locally produced, killed, oral cholera vaccine in Vietnam

21 January 2018

1 reference

21 January 2018

1 reference

New-generation vaccines against cholera

21 January 2018

1 reference

Infectious diarrhea: Cellular and molecular mechanisms

21 January 2018

1 reference

Protection and attachment of Vibrio cholerae mediated by the toxin-coregulated pilus in the infant mouse model

21 January 2018

1 reference

Cholera toxin structure, gene regulation and pathophysiological and immunological aspects

21 January 2018

1 reference

Vibrio cholerae infection, novel drug targets and phage therapy

21 January 2018

1 reference

Regulation of virulence in Vibrio cholerae: the ToxR regulon

21 January 2018

1 reference

Vibrio cholerae interactions with the gastrointestinal tract: lessons from animal studies.

21 January 2018

1 reference

From motility to virulence: sensing and responding to environmental signals in Vibrio cholerae

21 January 2018

1 reference

Energy transducing redox steps of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae

21 January 2018

1 reference

Alternative sigma factors and their roles in bacterial virulence

21 January 2018

1 reference

Effects of changes in membrane sodium flux on virulence gene expression in Vibrio cholerae

21 January 2018

1 reference

The Vibrio cholerae flagellar regulatory hierarchy controls expression of virulence factors

21 January 2018

1 reference

Intestinal ion transport and the pathophysiology of diarrhea

21 January 2018

1 reference

Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport

21 January 2018

1 reference

KCNQ1-dependent transport in renal and gastrointestinal epithelia

21 January 2018

1 reference

Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization

21 January 2018

1 reference

Virstatin inhibits dimerization of the transcriptional activator ToxT

21 January 2018

1 reference

Capsaicin, a potential inhibitor of cholera toxin production in Vibrio cholerae

21 January 2018

1 reference

H-NS binding and repression of the ctx promoter in Vibrio cholerae

21 January 2018

1 reference

The role and specificity of the catalytic and regulatory cation-binding sites of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae

21 January 2018

1 reference

TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae

21 January 2018

1 reference

A high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio cholerae

21 January 2018

1 reference

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide

21 January 2018

1 reference

Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes

21 January 2018

1 reference

3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies

21 January 2018

1 reference

Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin

21 January 2018

1 reference

Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin

21 January 2018

1 reference

Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER.

21 January 2018

1 reference

Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

21 January 2018

1 reference

BiP‐dependent export of cholera toxin from endoplasmic reticulum‐derived microsomes

21 January 2018

1 reference

Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins

21 January 2018

1 reference

Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)

21 January 2018

1 reference

Structural and functional interactions between the cholera toxin A1 subunit and ERdj3/HEDJ, a chaperone of the endoplasmic reticulum

21 January 2018

1 reference

The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation

21 January 2018

1 reference

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

21 January 2018

1 reference

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p

21 January 2018

1 reference

TorsinA participates in endoplasmic reticulum-associated degradation

21 January 2018

1 reference

Cholera toxin up-regulates endoplasmic reticulum proteins that correlate with sensitivity to the toxin

21 January 2018

1 reference

Derlin-1 facilitates the retro-translocation of cholera toxin

21 January 2018

1 reference

Hsp90 is required for transfer of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm

21 January 2018

1 reference

Conformational instability of the cholera toxin A1 polypeptide

21 January 2018

1 reference

Stabilization of the tertiary structure of the cholera toxin A1 subunit inhibits toxin dislocation and cellular intoxication

21 January 2018

1 reference

A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunit

21 January 2018

1 reference

Contribution of Subdomain Structure to the Thermal Stability of the Cholera Toxin A1 Subunit

21 January 2018

1 reference

Resveratrol, a natural polyphenolic compound, inhibits cholera toxin-induced cyclic AMP accumulation in Vero cells

21 January 2018

1 reference

Differential activities of plant polyphenols on the binding and internalization of cholera toxin in vero cells

21 January 2018

1 reference

Inhibition by apple polyphenols of ADP-ribosyltransferase activity of cholera toxin and toxin-induced fluid accumulation in mice

21 January 2018

1 reference

Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction

21 January 2018

1 reference

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

21 January 2018

1 reference

Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea

21 January 2018

1 reference

Thiophenecarboxylate suppressor of cyclic nucleotides discovered in a small-molecule screen blocks toxin-induced intestinal fluid secretion

21 January 2018

1 reference

Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretion

21 January 2018

1 reference

Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners

21 January 2018

1 reference

Electrolyte transport in the mammalian colon: mechanisms and implications for disease

21 January 2018

1 reference

Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides

21 January 2018

1 reference

Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera.

21 January 2018

1 reference

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

21 January 2018

1 reference

Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor

21 January 2018

1 reference

In vivo pharmacology and antidiarrheal efficacy of a thiazolidinone CFTR inhibitor in rodents

21 January 2018

1 reference

Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy

21 January 2018

1 reference

A plant-derived hydrolysable tannin inhibits CFTR chloride channel: a potential treatment of diarrhea

21 January 2018

1 reference

Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease

21 January 2018

1 reference

Stevioside and related compounds: therapeutic benefits beyond sweetness

21 January 2018

1 reference

A natural plant-derived dihydroisosteviol prevents cholera toxin-induced intestinal fluid secretion

21 January 2018

1 reference

The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa

21 January 2018

1 reference

Hemolysin and the multifunctional autoprocessing RTX toxin are virulence factors during intestinal infection of mice with Vibrio cholerae El Tor O1 strains

21 January 2018

1 reference

The active Zot domain (aa 288–293) increases ZO‐1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO‐1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation

21 January 2018

1 reference

Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette

21 January 2018

1 reference

Long-term effectiveness against cholera of oral killed whole-cell vaccine produced in Vietnam

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.13.42

1 reference

28 August 2017

1 reference