(Q38155597)

29 August 2017

title

Cause and consequence of cancer/testis antigen activation in cancer (English)

1 reference

29 August 2017

Cause and Consequence of Cancer/Testis Antigen Activation in Cancer (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

neoplastic gene expression regulation

30 April 2025

main subject

object named as

gene expression regulation, neoplastic

object of statement has role

Medical Subject Headings

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A24160706

30 April 2025

1

Angelique W Whitehurst

1 reference

29 August 2017

author name string

Angelique W. Whitehurst

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A24160706

30 April 2025

publication date

11 October 2013

1 reference

29 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=24160706

https://www.annualreviews.org/doi/pdf/10.1146/annurev-pharmtox-011112-140326

30 April 2025

work available at URL

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A24160706

Annual Review of Pharmacology and Toxicology

30 April 2025

published in

1 reference

29 August 2017

volume

54

1 reference

29 August 2017

page(s)

251-272

1 reference

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

29 August 2017

cites work

1 reference

31 March 2022

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The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

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24 May 2022

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Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells

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Journal of the National Cancer Institute

30 April 2025

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1957

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Teratocarcinoma cell variants rejected by syngeneic mice: protection of mice immunized with these variants against other variants and against the original malignant cell line

30 April 2025

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis

30 April 2025

5

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Association of class I major histocompatibility heavy and light chains induced by viral peptides

30 April 2025

8

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification of classical minor histocompatibility antigen as cell-derived peptide

30 April 2025

9

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cellular peptide composition governed by major histocompatibility complex class I molecules

30 April 2025

10

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

30 April 2025

11

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus

30 April 2025

12

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Induction of T cells specific for the mutated segment of oncogenic P21ras protein by immunization in vivo with the oncogenic protein

30 April 2025

15

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification of two cytotoxic T lymphocyte-recognized epitopes in the Ras protein

30 April 2025

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse

30 April 2025

17

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

T-cell immunity to the joining region of p210BCR-ABL protein

30 April 2025

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen

30 April 2025

20

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

30 April 2025

22

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Structure, chromosomal localization, and expression of 12 genes of the MAGE family

30 April 2025

23

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

30 April 2025

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification of a meiosis-specific protein as a member of the class of cancer/testis antigens

30 April 2025

27

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

30 April 2025

28

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Human neoplasms elicit multiple specific immune responses in the autologous host

30 April 2025

29

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens

30 April 2025

30

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Genome-wide analysis of cancer/testis gene expression

30 April 2025

31

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cancer/testis antigens, gametogenesis and cancer

30 April 2025

32

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

30 April 2025

33

1

1

Old LJ

2001

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of MAGE genes in primary and metastatic cutaneous melanoma

30 April 2025

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

CT-X antigen expression in human breast cancer.

30 April 2025

36

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

ONCOMINE: a cancer microarray database and integrated data-mining platform

30 April 2025

37

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors

30 April 2025

38

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

30 April 2025

39

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

MAGE, BAGE andGAGE gene expression in human rhabdomyosarcomas

30 April 2025

40

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of multiple cancer/testis (CT) antigens in breast cancer and melanoma: Basis for polyvalent CT vaccine strategies

30 April 2025

41

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

MAGE-C2/CT10 Protein Expression Is an Independent Predictor of Recurrence in Prostate Cancer

30 April 2025

42

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Immunological, paracrine and endocrine aspects of testicular immune privilege.

30 April 2025

44

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Ocular autoimmunity: the price of privilege?

30 April 2025

45

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Aire and T cell development

30 April 2025

46

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters

30 April 2025

47

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

30 April 2025

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

30 April 2025

Aire: an update.

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Aire regulates negative selection of organ-specific T cells

30 April 2025

50

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

30 April 2025

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Characterization of mutations in patients with autoimmune polyglandular syndrome type 1 (APS1).

30 April 2025

52

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mutation analyses of North American APS-1 patients

30 April 2025

53

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Comprehensive genomic characterization of squamous cell lung cancers

30 April 2025

54

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy

30 April 2025

56

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification of cancer/testis-antigen genes by massively parallel signature sequencing

30 April 2025

57

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research

30 April 2025

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

MAGE A3 antigen-specific cancer immunotherapeutic

30 April 2025

59

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma

30 April 2025

60

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cancer/testis antigen CT45: analysis of mRNA and protein expression in human cancer

30 April 2025

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours

30 April 2025

62

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

30 April 2025

64

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells

30 April 2025

65

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b

30 April 2025

66

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A novel cancer/testis antigen KP-OVA-52 identified by SEREX in human ovarian cancer is regulated by DNA methylation

30 April 2025

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

30 April 2025

69

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma

30 April 2025

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells

30 April 2025

72

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor

30 April 2025

73

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

30 April 2025

74

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1.

30 April 2025

75

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer

30 April 2025

76

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC.

30 April 2025

77

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression

30 April 2025

78

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells

30 April 2025

79

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells

30 April 2025

80

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells

30 April 2025

81

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine.

30 April 2025

82

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy

30 April 2025

83

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene.

30 April 2025

84

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Increased expression of androgen receptor coregulator MAGE-11 in prostate cancer by DNA hypomethylation and cyclic AMP.

30 April 2025

85

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Dynamic transcriptional regulatory complexes including BORIS, CTCF and Sp1 modulate NY-ESO-1 expression in lung cancer cells

30 April 2025

86

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors

30 April 2025

87

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer

30 April 2025

88

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

30 April 2025

89

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes

30 April 2025

90

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma

30 April 2025

92

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer

30 April 2025

94

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Human chorionic gonadotropin-beta subunit gene expression in cultured human fetal and cancer cells of different types and origins

30 April 2025

95

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Human chorionic gonadotropin expression by bladder cancers: biology and clinical potential

30 April 2025

96

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Human chorionic gonadotropin in cancer

30 April 2025

97

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Molecular beacon reverse transcription-PCR of human chorionic gonadotropin-beta-3, -5, and -8 mRNAs has prognostic value in breast cancer

30 April 2025

98

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors

30 April 2025

101

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

30 April 2025

102

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Small-molecule inhibition of BRDT for male contraception

30 April 2025

103

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Selective inhibition of BET bromodomains

30 April 2025

104

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling

30 April 2025

105

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells

30 April 2025

106

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission

30 April 2025

107

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Centrosomal Protein 55 (Cep55) Stability Is Negatively Regulated by p53 Protein through Polo-like Kinase 1 (Plk1)

30 April 2025

108

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Tex14, a Plk1-Regulated Protein, Is Required for Kinetochore-Microtubule Attachment and Regulation of the Spindle Assembly Checkpoint

30 April 2025

109

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates

30 April 2025

110

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

KNL1/Spc105 Recruits PP1 to Silence the Spindle Assembly Checkpoint

30 April 2025

111

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells

30 April 2025

112

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment

30 April 2025

113

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells

30 April 2025

114

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Deviant kinetochore microtubule dynamics underlie chromosomal instability.

30 April 2025

115

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Spindle multipolarity is prevented by centrosomal clustering.

30 April 2025

116

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Tumor Antigen Acrosin Binding Protein Normalizes Mitotic Spindle Function to Promote Cancer Cell Proliferation

30 April 2025

117

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm

30 April 2025

118

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The centrosomal localization of KM-HN-1 (MGC33607) depends on the leucine zipper motif and the C-terminal coiled-coil domain

30 April 2025

119

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Novel centrosome protein, TCC52, is a cancer-testis antigen

30 April 2025

120

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit

30 April 2025

121

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

30 April 2025

122

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

30 April 2025

123

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development

30 April 2025

124

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Cytochrome c oxidase of mammals contains a testes-specific isoform of subunit VIb--the counterpart to testes-specific cytochrome c?

30 April 2025

125

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Factors maintaining normal sperm tail structure during epididymal maturation studied in Gopc-/- mice

30 April 2025

126

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

LDHC: the ultimate testis-specific gene

30 April 2025

127

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Lactate dehydrogenase C and energy metabolism in mouse sperm

30 April 2025

128

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Properties of the testicular lactate dehydrogenase isoenzyme

30 April 2025

129

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Developmentally regulated piRNA clusters implicate MILI in transposon control

30 April 2025

130

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile

30 April 2025

131

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mili, a mammalian member of piwi family gene, is essential for spermatogenesis

30 April 2025

132

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Chromatoid body and small RNAs in male germ cells

30 April 2025

133

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis

30 April 2025

134

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression

30 April 2025

135

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of MAEL in nuage and non-nuage compartments of rat spermatogenic cells and colocalization with DDX4, DDX25 and MIWI

30 April 2025

136

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Piwil2 Suppresses P53 by Inducing Phosphorylation of Signal Transducer and Activator of Transcription 3 in Tumor Cells

30 April 2025

137

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Fibrous sheath of mammalian spermatozoa

30 April 2025

138

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum

30 April 2025

139

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification and characterization of RHOA-interacting proteins in bovine spermatozoa

30 April 2025

140

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity

30 April 2025

142

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Minireview: PRKAR1A: normal and abnormal functions

30 April 2025

143

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Rho GTPases in cancer cell biology

30 April 2025

144

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

ATM controls meiotic double-strand-break formation

30 April 2025

145

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The mouse Spo11 gene is required for meiotic chromosome synapsis

30 April 2025

146

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation

30 April 2025

147

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility

30 April 2025

148

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair

30 April 2025

149

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

30 April 2025

150

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

30 April 2025

151

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

30 April 2025

152

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

An oncogene-induced DNA damage model for cancer development

30 April 2025

153

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis

30 April 2025

154

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Calsperin is a testis-specific chaperone required for sperm fertility

30 April 2025

155

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Plac1 (placenta‐specific 1) is essential for normal placental and embryonic development

30 April 2025

156

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility

30 April 2025

157

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Loss of ASP but not ROPN1 reduces mammalian ciliary motility

30 April 2025

158

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Impaired sperm aggregation in Adam2 and Adam3 null mice

30 April 2025

159

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm penetration of the zona pellucida

30 April 2025

160

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis

30 April 2025

161

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Identification of morc (microrchidia), a mutation that results in arrest of spermatogenesis at an early meiotic stage in the mouse

30 April 2025

162

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS.

30 April 2025

163

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

The first bromodomain of Brdt, a testis-specific member of the BET sub-family of double-bromodomain-containing proteins, is essential for male germ cell differentiation

30 April 2025

164

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis

30 April 2025

165

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

30 April 2025

166

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Male Mice Lacking the Theg (Testicular Haploid Expressed Gene) Protein Undergo Normal Spermatogenesis and Are Fertile1

30 April 2025

167

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Generation and characterization of Tmeff2 mutant mice

30 April 2025

168

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Inactivation of Nxf2 causes defects in male meiosis and age-dependent depletion of spermatogonia

30 April 2025

169

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Expression of the gene for mouse lactate dehydrogenase C (Ldhc) is required for male fertility

30 April 2025

170

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

A gene trap knockout of the abundant sperm tail protein, outer dense fiber 2, results in preimplantation lethality

30 April 2025

171

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

Abnormal sperm in mice lacking the Taf7l gene

30 April 2025

172

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-PHARMTOX-011112-140326

30 April 2025

Identifiers

1 reference

29 August 2017

1 reference