(Q38199547)

30 August 2017

Animal models of urinary bladder cancer and their application to novel drug discovery (English)

1 reference

Carmen Vasconcelos-Nóbrega

30 August 2017

1 reference

1 reference

series ordinal

3

object named as

Carmen Vasconcelos-Nóbrega

1 reference

30 August 2017

Paula A Oliveira

1

1 reference

PubMed ID

24670247

30 August 2017

Regina Arantes-Rodrigues

series ordinal

2

1 reference

PubMed ID

24670247

30 August 2017

language of work or name

English

0 references

publication date

26 March 2014

1 reference

Expert Opinion on Drug Discovery

30 August 2017

1 reference

30 August 2017

9

1 reference

30 August 2017

485-503

1 reference

30 August 2017

5

1 reference

Epidemiology and genetic susceptibility to bladder cancer

30 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Bladder cancer epidemiology and genetic susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Strategies to improve drug delivery in bladder cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Radical cystectomy for invasive bladder cancer: long-term results of a standard procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Novel targeted agents for the treatment of bladder cancer: translating laboratory advances into clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Diagnosis and management of urothelial carcinoma of the bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Maintenance Bacillus Calmette-Guerin for Ta T1 Bladder Tumors Is Not Associated with Increased Toxicity: Results from a European Organisation for Research and Treatment of Cancer Genito-Urinary Group Phase III Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A single immediate postoperative instillation of chemotherapy decreases the risk of recurrence in patients with stage Ta T1 bladder cancer: a meta-analysis of published results of randomized clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemotherapy in advanced bladder cancer: current status and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Modelling breast cancer: one size does not fit all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Organotypic and 3D reconstructed cultures of the human bladder and urinary tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Experimental animal model and RNA interference: a promising association for bladder cancer research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Characterization of a novel transplantable orthotopic rat bladder transitional cell tumour model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Experimental rat bladder urothelial cell carcinoma models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Comparative pathology of proliferative lesions of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Bladder Consensus Conference Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

The use of animal models for cancer chemoprevention drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Why transgenic and knockout animal models should be used (for drug efficacy studies in cancer).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Assessing new anti-tumour agents and strategies in oncogene transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Predictive in vivo animal models and translation to clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A Human Tissue Culture Cell Line from a Transitional Cell Tumour of the Urinary Bladder: Growth, Chromosome Pattern and Ultrastructure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Animal models of disease: pre-clinical animal models of cancer and their applications and utility in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Cytogenetic characterization of an N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse papillary urothelial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of urinary bladder carcinogenesis by aqueous extract of sclerotia of Polyporus umbellatus fries and polyporus polysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of two-step urinary bladder carcinogenesis by the somatostatin analogue RC-160.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Anti-promoting effect of nordihydroguaiaretic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine and sodium saccharin-induced rat urinary bladder carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive efficacy of piroxicam administered alone or in combination with lycopene and beta-carotene on the development of rat urinary bladder carcinoma after N-butyl-N-(4-hydroxybutyl)nitrosamine treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive effects of bovine lactoferrin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Omega-3 fatty acids inhibit tumor growth in a rat model of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive efficacy of Atorvastatin against nitrosamine-induced rat bladder cancer: antioxidant, anti-proliferative and anti-inflammatory properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive property of dietary ginger in rat urinary bladder chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Preventive effects of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rat by green tea leaves

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine on bladder cancer in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibitory effect of clotrimazole on angiogenesis associated with bladder epithelium proliferation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Anti-angiogenic effects of the superantigen staphylococcal enterotoxin B and bacillus Calmette-Guérin immunotherapy for nonmuscle invasive bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effects of vitamin D (calcitriol) on transitional cell carcinoma of the bladder in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of tumor angiogenesis during cisplatin chemotherapy for bladder cancer improves treatment outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effect of indomethacin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced urinary tract carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

In vivo and in vitro effects of RAD001 on bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of bladder tumour growth by histone deacetylase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Synergistic antitumor effects of fleroxacin with 5-fluorouracil in vitro and in vivo for bladder cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Chemoprevention of BBN-Induced Bladder Carcinogenesis by the Selective Estrogen Receptor Modulator Tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Expression of basic fibroblast growth factor is associated with resistance to cisplatin in a human bladder cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Angiotensin II type 1 receptor antagonist enhances cis-dichlorodiammineplatinum-induced cytotoxicity in mouse xenograft model of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Schedule dependent efficacy of gefitinib and docetaxel for bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effect of angiotensin II type 1 receptor antagonist on tumor growth and angiogenesis in a xenograft model of human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

1,25D3 enhances antitumor activity of gemcitabine and cisplatin in human bladder cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Potential anticancer activity of myricetin in human T24 bladder cancer cells both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

NS-398, a selective cyclooxygenase-2 inhibitor, reduces experimental bladder carcinoma outgrowth by inhibiting tumor cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Cyclooxygenase inhibitors in urinary bladder cancer: in vitro and in vivo effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Enhanced antitumor effect of coincident intravesical gemcitabine plus BCG therapy in an orthotopic bladder cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antineoplastic effect of gemcitabine in an animal model of superficial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antitumor effects of recombinant BCG and interleukin-12 DNA vaccines on xenografted murine bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antineoplastic activity of honey in an experimental bladder cancer implantation model: in vivo and in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Tumour growth inhibition by an imidazoquinoline is associated with c-Myc down-regulation in urothelial cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Allium sativum potentiates suicide gene therapy for murine transitional cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Immunotherapeutic effect of Concholepas hemocyanin in the murine bladder cancer model: evidence for conserved antitumor properties among hemocyanins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Cortisone inhibition of tumor angiogenesis measured by a quantitative colorimetric assay in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A comparative study of the inhibiting effects of mitomycin C and polyphenolic catechins on tumor cell implantation/growth in a rat bladder tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Antitumor Efficacy of Intravesical BCG, Gemcitabine, Interferon-α and Interleukin-2 as Mono- or Combination-Therapy for Bladder Cancer in an Orthotopic Tumor Model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of bladder cancer development by allyl isothiocyanate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Inhibition of tumor implantation by intravesical gemcitabine in a murine model of superficial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Effects of curcumin in an orthotopic murine bladder tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Intravesical Toll-like receptor 7 agonist R-837: optimization of its formulation in an orthotopic mouse model of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

HAMLET treatment delays bladder cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2014.902930

10.1517/17460441.2014.902930

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference

PubMed ID

24670247