(Q38255378)

1 September 2017

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title

The mammalian Hippo pathway: regulation and function of YAP1 and TAZ. (English)

1 reference

1 September 2017

Manami Kodaka

1

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1 September 2017

Yutaka Hata

series ordinal

2

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1 September 2017

publication date

30 September 2014

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Cellular and Molecular Life Sciences

1 September 2017

published in

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1 September 2017

volume

72

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1 September 2017

issue

2

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1 September 2017

page(s)

285-306

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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation

1 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mst1 and Mst2 kinases: regulations and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A regulatory circuit controlling Itch-mediated p73 degradation by Runx.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Nek1 and TAZ interact to maintain normal levels of polycystin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap1 acts downstream of α-catenin to control epidermal proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

PTPN14 is required for the density-dependent control of YAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Control of the hippo pathway by Set7-dependent methylation of Yap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Molecular insights into NF2/Merlin tumor suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Angiomotins--from discovery to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo pathway-independent restriction of TAZ and YAP by angiomotin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Ajuba LIM proteins are negative regulators of the Hippo signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of YAP by mechanical strain through Jnk and Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ interacts with zonula occludens‐1 and ‐2 proteins in a PDZ‐1 dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Role of YAP/TAZ in mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Metabolic control of YAP and TAZ by the mevalonate pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Homeodomain-interacting protein kinase regulates Hippo pathway-dependent tissue growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Drosophila RASSF homolog antagonizes the hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

RASSF tumor suppressor gene family: biological functions and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Identification of a novel Ras-regulated proapoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

RASSF2 associates with and stabilizes the proapoptotic kinase MST2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Role of the tumor suppressor RASSF2 in regulation of MST1 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Selenoprotein W enhances skeletal muscle differentiation by inhibiting TAZ binding to 14-3-3 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mask is required for the activity of the Hippo pathway effector Yki/YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mask proteins are cofactors of Yorkie/YAP in the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

SOX2 regulates YAP1 to maintain stemness and determine cell fate in the osteo-adipo lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Emerging roles of TEAD transcription factors and its coactivators in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Structural basis of YAP recognition by TEAD4 in the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Structural insights into the YAP and TEAD complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Structural and functional analysis of the YAP-binding domain of human TEAD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The TEAD4-YAP/TAZ protein-protein interaction: expected similarities and unexpected differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Transcriptional activity of Pax3 is co-activated by TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo pathway regulates Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Restriction of intestinal stem cell expansion and the regenerative response by YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP1 increases organ size and expands undifferentiated progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Role of TAZ as mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP regulates neuronal differentiation through Sonic hedgehog signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

KRAS and YAP1 converge to regulate EMT and tumor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Cytokinesis failure triggers hippo tumor suppressor pathway activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of gene expression at the beginning of mammalian development and the TEAD family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo pathway member Nf2 is required for inner cell mass specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

21 January 2018

The NuRD architecture

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo pathway effector Yap promotes cardiac regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo signaling regulates differentiation and maintenance in the exocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo signaling regulates pancreas development through inactivation of Yap.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yes-associated protein regulates the hepatic response after bile duct ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo pathway activity influences liver cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Lats2 is a negative regulator of myocyte size in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap controls stem/progenitor cell proliferation in the mouse postnatal epidermis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP and TAZ regulate skin wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

YAP regulates neural progenitor cell number via the TEA domain transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Lats2 modulates adipocyte proliferation and differentiation via hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yap is a novel regulator of C2C12 myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Novel TAZ modulators enhance myogenic differentiation and muscle regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

The Hippo signaling pathway interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Defining the protein-protein interaction network of the human hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Label-free quantitative proteomic analysis of the YAP/TAZ interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1742-9

Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size

21 January 2018

1 reference

12 December 2020

Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration

1 reference

12 December 2020

YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression

1 reference

12 December 2020

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis

1 reference

12 December 2020

Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF

1 reference

12 December 2020

Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product

1 reference

12 December 2020

A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.

1 reference

12 December 2020

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

1 reference

12 December 2020

Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer

1 reference

12 December 2020

Ajuba family proteins link JNK to Hippo signaling.

1 reference

12 December 2020

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

1 reference

12 December 2020

The surprising features of the TEAD4-Vgll1 protein-protein interaction

1 reference

12 December 2020

10.1007/S00018-014-1742-9

Identifiers

DOI

1 reference

1 September 2017

1 reference