(Q38255435)

1 September 2017

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title

The insulin secretory granule (English)

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1 September 2017

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1

J C Hutton

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publication date

1 May 1989

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1 September 2017

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1 September 2017

32

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1 September 2017

271-281

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1 September 2017

5

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https://scigraph.springernature.com/pub.10.1007/bf00265542

1 September 2017

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cites work

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12 December 2020

Ca2+-dependent binding of cytosolic components to insulin-secretory granules results in Ca2+-dependent protein phosphorylation

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12 December 2020

Physicochemical characteristics of insulin secretion granules

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12 December 2020

Primary structure of rat chromogranin A and distribution of its mRNA.

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Biochemical and clinical implications of proinsulin conversion intermediates

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5-Hydroxytryptamine transport in cells and secretory granules from a transplantable rat insulinoma

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Biosynthesis of betagranin in pancreatic beta-cells. Identification of a chromogranin A-like precursor and its parallel processing with proinsulin.

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Insulin secretion by a transplantable rat islet cell tumour

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Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion

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Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

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Immunolocalization of betagranin: a chromogranin A-related protein of the pancreatic B-cell.

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Nucleotide and bivalent cation specificity of the insulin-granule proton translocase

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Post-translational proteolysis in polypeptide hormone biosynthesis

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THE RELATION OE DIABETES MELLITUS TO LESIONS OF THE PANCREAS. HYALINE DEGENERATION OF THE ISLANDS OE LANGERHANS.

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Low-molecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphate

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Proteolytic processing of chromogranin A in purified insulin granules. Formation of a 20 kDa N-terminal fragment (betagranin) by the concerted action of a Ca2+-dependent endopeptidase and carboxypeptidase H (EC 3.4.17.10)

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A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas

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The electron microscopic localization of cations to pancreatic islets of langerhans and their possible role in insulin secretion

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Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

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Localization of pancreastatin immunoreactivity in porcine endocrine cells

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Cell surface receptors for extracellular matrix molecules

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Evidence for high peptide α-amidation activity in the neonatal rat pancreas

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12 December 2020

Calcium and pancreatic β-cell function6. glucose and intracellular 45Ca distribution

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Acidification of the endocytic and exocytic pathways

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12 December 2020

Demonstration of a proton gradient across the insulin granule membrane

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12 December 2020

Proton-translocating ATPases

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12 December 2020

Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones

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Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

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Production and characterization of monoclonal antibodies to insulin secretory granule membranes

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ISOLATION AND CULTURE OF THE ISLETS OF LANGERHANS OF THE GUINEA PIG

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The internal pH and membrane potential of the insulin-secretory granule

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Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

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Calcium-dependent KEX2-like protease found in hepatic secretory vesicles converts proalbumin to albumin.

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Isolation and properties of secretory granules from rat islets of Langerhans. 3. Studies of the stability of the isolated beta granules

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The biosociology of pancreatic B cells

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A transplantable insulinoma in the rat

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Involvement of protein kinase C in the phosphorylation of an insulin-granule membrane protein

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Differences in the nature of the interaction of insulin and proinsulin with zinc

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Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance

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Conversion of proinsulin to insulin in a subcellular fraction from rat islets

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Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content

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Calcium-binding proteins and secretion

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The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing

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beta-Granins: 21 kDa co-secreted peptides of the insulin granule closely related to adrenal medullary chromogranin A

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The molecular cloning of the chromogranin A-like precursor of beta-granin and pancreastatin from the endocrine pancreas

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12 December 2020

Isolation and characterisation of insulin secretory granules from a rat islet cell tumour

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Ca2+-sensitive phosphatidylinositol 4-phosphate metabolism in a rat β-cell tumour

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Calcium distribution in islets of Langerhans: a study of calcium concentrations and of calcium accumulation in B cell organelles

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12 December 2020

Evidence of beta cell dysfunction which does not lead on to diabetes: a study of identical twins of insulin dependent diabetics

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12 December 2020

Proteolytic conversion of proinsulin into insulin. Identification of a Ca2+-dependent acidic endopeptidase in isolated insulin-secretory granules

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12 December 2020

Biosynthesis of insulin secretory granule membrane proteins. Control by glucose.

1 reference

12 December 2020

Proton-translocating Mg2+-dependent ATPase activity in insulin-secretory granules

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12 December 2020

The discovery of pancreatic diabetes; the role of Oscar Minkowski

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12 December 2020

The insulin cell: its cellular environment and how it processes (pro)insulin

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12 December 2020

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12 December 2020

Pancreatic B-cells secrete a range of novel peptides besides insulin

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12 December 2020

Identifiers

DOI

10.1007/BF00265542

1 reference

PubMed ID

2526768

Dimensions Publication ID

1 September 2017

0 references

1 reference

PubMed ID

2526768