(Q38292039)

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A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors

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scholarly article

1 reference

Europe PubMed Central

1 September 2017

A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors (English)

1 reference

Europe PubMed Central

1 September 2017

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Escherichia coli

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based on heuristic

inferred from title

3

object named as

Osheroff N

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Europe PubMed Central

1 September 2017

author name string

Hsiung Y

1

1 reference

Europe PubMed Central

1 September 2017

Elsea SH

2

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Europe PubMed Central

1 September 2017

Nitiss JL

4

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Europe PubMed Central

1 September 2017

language of work or name

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publication date

1 September 1995

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Europe PubMed Central

1 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

1 September 2017

270

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Europe PubMed Central

1 September 2017

20359-20364

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Europe PubMed Central

1 September 2017

35

1 reference

Europe PubMed Central

1 September 2017

Recent studies of DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

DNA topoisomerase II is required at the time of mitosis in yeast

1 reference

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21 January 2018

Coming undone: how to untangle a chromosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

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Inhibitors of DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

DNA topoisomerase poisons as antitumor drugs

1 reference

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21 January 2018

Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

DNA gyrase: structure and function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Isolation and characterization of yeast DNA repair genes : I. Cloning of the RAD52 gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Incomplete reversion of double stranded DNA cleavage mediated by Drosophila topoisomerase II: formation of single stranded DNA cleavage complex in the presence of an anti-tumor drug VM26

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Tandem regions of yeast DNA topoisomerase II share homology with different subunits of bacterial gyrase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.35.20359

21 January 2018

Identifiers

10.1074/JBC.270.35.20359

1 reference

Europe PubMed Central

1 September 2017

1 reference

Europe PubMed Central

1 September 2017

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