(Q38344807)

English

Discreet mutations from c-Rel to v-Rel alter kappaB DNA recognition, IkappaBalpha binding, and dimerization: implications for v-Rel oncogenicity

scientific article published on February 2004

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scholarly article

1 reference

Europe PubMed Central

2 September 2017

Discreet mutations from c-Rel to v-Rel alter kappaB DNA recognition, IkappaBalpha binding, and dimerization: implications for v-Rel oncogenicity (English)

1 reference

Europe PubMed Central

2 September 2017

author name string

Christopher B Phelps

1

1 reference

Europe PubMed Central

2 September 2017

Gourisankar Ghosh

2

1 reference

Europe PubMed Central

2 September 2017

language of work or name

0 references

publication date

1 February 2004

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

23

1 reference

Europe PubMed Central

2 September 2017

1229-1238

1 reference

Europe PubMed Central

2 September 2017

6

1 reference

Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207242

0 references

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Preparation and crystallization of dynamic NF-kappa B.Ikappa B complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

NF-kappaB regulation in the immune system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

Structure, regulation and function of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

21 January 2018

NF-kappa B: ten years after

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear factor-kappa B and cancer: its role in prevention and therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Construction, expression, purification and functional analysis of recombinant NFkappaB p50/p65 heterodimer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel DNA recognition mode by the NF-kappa B p65 homodimer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB p65 (RelA) homodimer uses distinct mechanisms to recognize DNA targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Avian reticuloendotheliosis virus-transformed lymphoid cells contain multiple pp59v-rel complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Envelope-dependent transactivation by the retroviral oncoprotein v-Rel is required for efficient malignant transformation of chicken spleen cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of NF-kappa B p50 homodimer bound to a kappa B site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Different localization of the product of the v-rel oncogene in chicken fibroblasts and spleen cells correlates with transformation by REV-T.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Transactivation of gene expression by nuclear and cytoplasmic rel proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon regulatory factor 4 contributes to transformation of v-Rel-expressing fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of an IkappaBalpha/NF-kappaB complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

AP-1 factors play an important role in transformation induced by the v-rel oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the NF-kappa B p50 homodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Differences in kappaB DNA-binding properties of v-Rel and c-Rel are the result of oncogenic mutations in three distinct functional regions of the Rel protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Achieving transcriptional specificity with NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of changes in gene expression associated with malignant transformation by the NF-kappaB family member, v-Rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of I kappa B alpha binding to NF-kappa B dimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the v-Rel transactivation domain indicate altered phosphorylation and identify a subset of NF-kappaB-regulated cell death inhibitors important for v-Rel transforming activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

A threshold nuclear level of the v-Rel oncoprotein is required for transformation of avian lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-Rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Avian I kappa B alpha is transcriptionally induced by c-Rel and v-Rel with different kinetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-specific association and shuttling of IkappaBalpha provides a mechanism for nuclear NF-kappaB in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207242

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207242

1 reference

Europe PubMed Central

2 September 2017

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1 reference

Europe PubMed Central

2 September 2017

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0 references

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